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Journal of Molecular Biology, 1996
Escherichia coli nusD strains are bacteria that carry mutations in rho, the gene for transcription termination factor Rho, that block the growth of phages T4 and lambdar32. We have identified the rho mutation in six independent nusD strains, and although five of the strains have different mutations, with one exception the mutations are in the proposed ...
R S, Washburn, B L, Stitt
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Escherichia coli nusD strains are bacteria that carry mutations in rho, the gene for transcription termination factor Rho, that block the growth of phages T4 and lambdar32. We have identified the rho mutation in six independent nusD strains, and although five of the strains have different mutations, with one exception the mutations are in the proposed ...
R S, Washburn, B L, Stitt
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Preventing the synthesis of unused transcripts by rho factor
Cell, 1991John P. Richardson Department of Chemistry Programs in Biochemistry and Molecular, Cellular and Developmental Biology Indiana University Bloomington, Indiana 47405 Transcriptional terminators have three important functions in gene expression. One is as asignal that defines the end of transcription unit for a gene or a group of genes.
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rho factor-dependent transcription termination. Interference by a mutant rho.
Journal of molecular biology, 1987The rho protein isolated from a strain of Escherichia coli with the rho1 (suA1) mutant allele is defective in interactions with RNA that are coupled to ATP hydrolysis. Here we show that the rho1 allele is partially dominant over wild-type and demonstrate that the mechanism of that dominance is due to an interference of wild-type rho factor function by ...
J P, Richardson, E C, Ruteshouser
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Transcription termination factor rho is an RNA-DNA helicase
Cell, 1987E. coli rho factor can unwind a short RNA-DNA duplex in vitro. The duplex is formed between a polylinker sequence at the 3' end of RNA derived from the rho-dependent terminator trp t' and the complementary sequence in a single-strand DNA molecule. Release of trp t' RNA from the duplex requires nucleoside triphosphate hydrolysis by rho's NTPase activity
C A, Brennan, A J, Dombroski, T, Platt
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Transcription termination factor Rho and microbial phenotypic heterogeneity
Current Genetics, 2017Populations of genetically identical microorganisms exhibit high degree of cell-to-cell phenotypic diversity even when grown in uniform environmental conditions. Heterogeneity is a genetically determined trait, which ensures bacterial adaptation and survival in the ever changing environmental conditions.
Elena Bidnenko, Vladimir Bidnenko
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Overproduction of transcription termination factor Rho in Escherichia coli
Gene, 1984A plasmid system has been constructed which allows high-level expression of the rho gene of Escherichia coli under the control of the pL promoter and the N-antitermination regulatory system of bacteriophage lambda. The pL-directed synthesis of Rho crucially depends on the lambda N gene product and is promoted most effectively when this product is ...
K, Shigesada +3 more
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Bacterial Virulence Factors and Rho GTPases
2005Foreword.- Bacterial Virulence strategies that utilize Rho GTPases.- Extracellular bacterial pathogens and small GTPases of the Rho family, an unexpected combination.- Triggered phagocytosis by Salmonella: bacterial molecular mimicry of Rho GTPase activation/deactivation.- Regulation of actin dynamics during phagocytosis by Rho GTPases.- The ...
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Rho GTPase signaling in cancer progression and dissemination
Physiological Reviews, 2022Eva Crosas-Molist +2 more
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The 'invisible hand': regulation of RHO GTPases by RHOGDIs
Nature Reviews Molecular Cell Biology, 2011Rafael García-Mata +2 more
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