Results 151 to 160 of about 104,378 (298)
Sustainable Development, EarlyView.ABSTRACT For service organizations like Online Food Delivery (OFD) services, sustainable development is increasingly becoming a necessity to meet customer expectations while addressing environmental and social sustainability issues. Therefore, these businesses must continuously adapt and innovate, and to do so, it is essential to understand consumer ...
Li Huang +3 more
wiley +1 more source
RHOA mutations and CLDN18-ARHGAP fusions in intestinal-type adenocarcinoma with anastomosing glands of the stomach [PDF]
, 2018 Taiki Hashimoto +7 more
openalex +1 more source
Ca2+/calmodulin/MLCK pathway initiates, and RhoA/ROCK maintains, the internal anal sphincter smooth muscle tone. [PDF]
, 2016 Rattan, Satish
core +2 more sources
Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases. [PDF]
, 2002 We show here the transient activation of the small GTPase Rac, followed by a rise in reactive oxygen species (ROS), as necessary early steps in a signal transduction cascade that lead to NFkappaB activation and collagenase-1 (CL-1)/matrix ...
Werb, Zena, Werner, Erica
core
UroPrecision, EarlyView.ABSTRACT Holmium laser enucleation of the prostate (HoLEP) has emerged as a widely adopted surgical technique for the management of benign prostatic hyperplasia (BPH), regardless of prostate size; however, its impact on male sexual function—particularly in terms of erectile and ejaculatory outcomes—remains a subject of ongoing debate.
Muhammed Arif İbiş +5 more
wiley +1 more source
Small Guanosine Triphospatase RhoA and Rho-Associated Kinase as Regulators of Trophoblast Migration [PDF]
, 2002 Shigetatsu Shiokawa +9 more
openalex +1 more source
Organoid‐based novel technology for antitumor drug screening
VIEW, EarlyView.Organoids represent a cutting‐edge research model that closely mimics in vivo organ physiology, making them highly valuable for tumor immunotherapy drug screening. This review explores the integration of organoids with advanced technologies, such as gene editing, 3D bioprinting, and AI, highlighting novel fusion platforms and their applications.
Yu Su +3 more
wiley +1 more source
Distinct Roles of IL‐4, IL‐13, and IL‐22 in Human Skin Barrier Dysfunction and Atopic Dermatitis
Allergy, EarlyView.This study reports the distinct effects of IL‐4, IL‐13, and IL‐22 on bio‐stabilized human skin with intact barriers and immune cells. IL‐4, IL‐13, and IL‐22 upregulate inflammatory mediators, disrupt skin barrier integrity, and reciprocally modulate IL‐4Rα and IL‐22Rα1 receptors.
Paolo D'Avino +12 more
wiley +1 more source
Allergy, EarlyView.Whole genome‐wide DNA methylation analysis of whole blood of patients undergoing 6 months of birch pollen subcutaneous allergen immunotherapy revealed epigenetic changes linked to allergen immunotherapy. Birch pollen AIT decreases methylation in HLA genes and induces methylation in genes associated with Th2 and TGF‐β pathways, increases CD8+ T cell ...
Angelika Lahnsteiner +8 more
wiley +1 more source