Results 171 to 180 of about 123,069 (394)
eLife, 2015 Cytokinesis requires activation of the GTPase RhoA. ECT-2, the exchange factor responsible for RhoA activation, is regulated to ensure spatiotemporal control of contractile ring assembly.
Donglei Zhang, Michael Glotzer
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Forsythoside A and Forsythoside B Contribute to Shuanghuanglian Injection-Induced Pseudoallergic Reactions through the RhoA/ROCK Signaling Pathway [PDF]
, 2019 Jiayin Han +13 more
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RhoA, RhoB and RhoC differentially regulate endothelial barrier function
Small GTPases, 2017 RhoGTPases are known regulators of intracellular actin dynamics that are important for maintaining endothelial barrier function. RhoA is most extensively studied as a key regulator of endothelial barrier function, however the function of the 2 highly ...
Manon C A Pronk +4 more
semanticscholar +1 more source
Anillin Puts RhoA in Touch with PIP2 [PDF]
Developmental Cell, 2019 In this issue of Developmental Cell, Budnar and colleagues report how the scaffolding protein anillin uses cycles of transient binding interactions to enhance the residence time and signaling output of active RhoA to control actomyosin contractility at epithelial junctions and during cell division.
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Arthritis &Rheumatology, Accepted Article.Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's Phenomenon (RP) and to explore their potential pathophysiological mechanisms through a mixed disproportionality/clustering analysis from the WHO pharmacovigilance database.
Alex Hlavaty +4 more
wiley +1 more source
Neoplasia: An International Journal for Oncology Research, 2008 RhoA is a critical signaling molecule regulating a variety of cellular processes, such as cytoskeletal organization, adhesion, and apoptosis. It is recently considered responsive to reactive oxygen species (ROS). Nevertheless, how RhoA regulates anoikis,
Jun Cai +7 more
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The Journal of Cell Biology, 2001 In fibroblasts, the small GTPase RhoA is required for the formation of integrin-containing adhesions. Surprisingly, Worthylake et al. (page 147) have found that RhoA serves a different purpose in monocytes, apparently operating as a negative regulator of integrin adhesions at the rear of migrating cells.
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ARC Expands the DAAM1 Microexon‐Mediated Actin–RHOA/ROCK Interplay
Cytoskeleton, EarlyView.ABSTRACT Actin cytoskeleton and its dynamics play a crucial role in synaptic function, influencing dendritic spines' structural and functional plasticity. Recent findings unveiled the significance of alternative splicing of a neural‐specific microexon in DAAM1 in modulating actin's role in synaptic processes.
Patryk Poliński +2 more
wiley +1 more source
RHOA mutations and CLDN18-ARHGAP fusions in intestinal-type adenocarcinoma with anastomosing glands of the stomach [PDF]
, 2018 Taiki Hashimoto +7 more
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Identification of novel genes regulating the development of the palate
Developmental Dynamics, EarlyView.Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley +1 more source