Results 241 to 250 of about 104,378 (298)

Mechanism of SC targeting RhoA regulation and its potential value in gastric cancer therapy. [PDF]

open access: yesBiochem Biophys Rep
Ma H   +7 more
europepmc   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

open access: hybrid
Sharda Yadav   +5 more
openalex   +1 more source

Neurovascular Coupling: Scientometric Analysis of 30 Years Research (1996–2025)

open access: yesBrain and Behavior, Volume 15, Issue 11, November 2025.
Bibliometric landscape of neurovascular coupling (1996–2025). This graphical abstract summarizes the bibliometric structure and intellectual evolution of the neurovascular coupling field. (A) Displays the number of publications and citations per year from 1996 to 2025. (B) Presents circular plot of international collaboration.
Xuenan Lang   +7 more
wiley   +1 more source

BUB1B Promotes Ovarian Cancer Cell Proliferation and Metastasis by Activating the Wnt/β‐Catenin Pathway

open access: yesCancer Medicine, Volume 14, Issue 21, November 2025.
ABSTRACT Background BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B) has been found to participate in cancer progression. Nevertheless, the function and mechanism of BUB1B in ovarian cancer (OC) remain unknown. Method Based on datasets GSE14407, GSE18520, and the TCGA combined GTEx database, the differently expressed genes (DEGs) between OC ...
Jing Wang, Xiaoling Su, Nan Lin, Tao Su
wiley   +1 more source

Exploring the mechanisms of mutual influence between lactylation and macrophage polarization in the context of disease

open access: yesClinical and Translational Medicine, Volume 15, Issue 11, November 2025.
The conversion of lactate to lactyl‐CoA facilitates enzymatic histone lactylation, transforming glycolytic by‐products into an epigenetic regulatory mechanism for gene expression. Lactylation modification influences macrophage polarization towards M1 or M2 phenotypes, affecting outcomes in infection, cancer and fibrosis. Targeting lactylation modifiers
Houhua Guo   +5 more
wiley   +1 more source

Mechanisms of lncRNA in Diabetic Foot Ulcer Wound Healing

open access: yesThe Journal of Gene Medicine, Volume 27, Issue 11, November 2025.
This review elucidates the critical roles of lncRNAs in regulating inflammation, angiogenesis, and extracellular matrix remodeling during diabetic foot ulcer healing. Key lncRNAs such as GAS5, H19, and MALAT1 modulate these processes by sponging miRNAs and targeting signaling pathways. We also discuss the therapeutic potential and current challenges of
Yiming Chen   +5 more
wiley   +1 more source

Research progress of ECT2 and RhoA-related signaling pathways in gynecological tumors. [PDF]

open access: yesFront Cell Dev Biol
Sheng L   +6 more
europepmc   +1 more source

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