Results 261 to 270 of about 123,069 (394)

A novel single-color FRET biosensor for Rho-kinase activity reveals calcium-dependent activation of RhoA and ROCK [PDF]

Allison E. Mancini, Megan A. Rizzo
openalex   +1 more source

p116Rip Decreases Myosin II Phosphorylation by Activating Myosin Light Chain Phosphatase and by Inactivating RhoA [PDF]

, 2004
Yasuhiko Koga, Mitsuo Ikebe
openalex   +1 more source

Kctd13 deletion reduces synaptic transmission via increased RhoA

Nature, 2017
Christine O. Escamilla, I. Filonova, Angela K. Walker, Zhong Xuan, R. Holehonnur, Felipe Espinosa, Shunan Liu, Summer B. Thyme, Isabel A. López-García, Dorian B. Mendoza, Noriyoshi Usui, J. Ellegood, A. Eisch, G. Konopka, J. Lerch, A. Schier, Haley E. Speed, C. Powell   +17 more
semanticscholar   +1 more source

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang, Tu Huang, Yi‐hang Hao, Min Zheng, Xin‐hua Liang   +4 more
wiley   +1 more source

Higenamine Hydrochloride Ameliorates Diabetic Cardiomyopathy Through RhoA/MEK/ERK Pathway. [PDF]

Inflammation
Li Y, Wang L, Guan T, Chen Y, Zhu W, Liu X, Li Y, Huang H, Dong Z, Zhang H.   +9 more
europepmc   +1 more source

RhoA/rock signaling mediates peroxynitrite-induced functional impairment of Rat coronary vessels [PDF]

, 2016
Zhijun Sun, Xing Wu, Weiping Li, Hui Peng, Xuhua Shen, Lu Ma, Huirong Liu, Hongwei Li   +7 more
openalex   +1 more source

RhoA/Rho-Kinase in the Cardiovascular System.

Circulation Research, 2016
H. Shimokawa, S. Sunamura, K. Satoh
semanticscholar   +1 more source

Development of Peptide Glucosyltransferase Inhibitors With Comprehensive Coverage Across Clostridioides difficile Toxin B Sub‐Types

Biotechnology and Bioengineering, Volume 123, Issue 2, Page 310-323, February 2026.
ABSTRACT Clostridioides difficile infection presents an escalating clinical challenge due to the proliferation of hypervirulent and antibiotic‐resistant strains. The primary symptoms of disease, namely colitis and diarrhea, are induced by the release of two toxins: TcdA and TcdB.
Carly M. Catella, Sudeep Sarma, Caroline M. Hinesley, Corey E. Febo, Keith A. Breau, Deniz Durmusoglu, Ethan Purnell, Scott T. Magness, Carol K. Hall, Stefano Menegatti, Nathan Crook   +10 more
wiley   +1 more source

Spatiotemporal coupling of caveolae mechanosensing and RhoA-GEFs regulates cell polarity and directional migration. [PDF]

Nat Commun
Singh V, Breton V, Viaris de Lesegno C, Macé AS, Bun P, Blouin CM, Vishen AS, Sens P, Lamaze C.   +8 more
europepmc   +1 more source

Hypercapnia Effects on Lung Function

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
CO2 is a signaling molecule that disrupts alveolar fluid clearance and ion transport, impairs alveolar repair, and promotes mitochondrial and endoplasmic reticulum dysfunction. It suppresses innate immunity, host defense, and inflammation, while increasing airway contractility.
Seungseo Choi, Laura A. Dada, Jacob I. Sznajder   +2 more
wiley   +1 more source