Results 281 to 290 of about 123,069 (394)

Oxypeucedanin attenuates neuropathic pain in male mice via inhibiting lysophosphatidic acid receptor signaling. [PDF]

iScience
Li J, Tang W, Wang L, Gu Y, You W, Yang W, Huang Y, Yu X, Zhu R, Xu Y, Li J, Zhu Q.   +11 more
europepmc   +1 more source

Curcumin Attenuates Intestinal Mucosal Barrier Dysfunction in Rats with Lactose-Induced Diarrhea via the RhoA/ROCK1 Pathway

, 2023
Qian Zhao, Yarui Li, Mudan Ren, Guifang Lu, Yan Zhao, Yaping Liu, Zhenwei Yang   +6 more
openalex   +1 more source

Primary Cutaneous Peripheral T‐Cell Lymphoma With Follicular Helper T‐Cell Phenotype

Journal of Cutaneous Pathology, Volume 53, Issue 2, Page 147-152, February 2026.
ABSTRACT An otherwise healthy 82‐year‐old woman presented with recurrent, asymptomatic erythematous papulo‐nodular lesions on the face and extremities. A skin biopsy revealed a dense, non‐epidermotropic lymphohistiocytic infiltrate with granulomatous features and a mixed population of medium‐sized atypical lymphoid cells and plasma cells ...
Nidia Planella‐Fontanillas, Andrea Molina‐Alvarez, Lluís Colomo‐Saperas, Roger Rovira, Monica Gonzàlez‐Farré, Carlos Barranco‐Sanz, Xavier Calvo, Clara Nadal‐Pellisé, Fernando Gallardo, Ramon M. Pujol   +9 more
wiley   +1 more source

Targeting RhoA nuclear mechanoactivity rejuvenates aged hematopoietic stem cells. [PDF]

Nat Aging
Mejía-Ramírez E, Picazo PI, Walter B, Montserrat-Vazquez S, Affuso F, Wieser S, Pezzano F, Reymond L, Castillo-Robles J, Matteini F, Mularoni L, Maciá D, Raya Á, Ruprecht V, Zheng Y, Petrone P, Florian MC.   +16 more
europepmc   +1 more source

Unlocking the Therapeutic Potential of Integrin‐Linked Kinase Inhibitors in Bioengineered 3D Breast Tumor Stroma Models

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
3D cancer models provide a more reliable representation of drug responses compared to 2D cell culture owing to their 3D architecture and facilitation of cell‐extracellular matrix interactions. In this study, we engineered dense compartmentalized 3D tumoroids composed of breast tumor mass and a surrounding stromal compartment replicating either breast ...
Salma T. Rafik, Anuja Upadhyay, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Effect of EphA2 Silencing on Inhibiting the Progression of Renal Cell Carcinoma in an Orthotopic Mouse Model. [PDF]

Cells
Lee T, Lee HS, Yoo S, Bae H, Cho MC, Lee J, Jeong H.   +6 more
europepmc   +1 more source

Biochemical and Physiological Effects of Galanin in Health and Disease

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles, Yubo Wang, Kathryn Rhodes, Sharon DeMorrow   +3 more
wiley   +1 more source

RhoA/Rho-Kinase Signaling in Vascular Smooth Muscle and Endothelium: Mechanistic Insights and Translational Implications in Hypertension. [PDF]

Biomolecules
Randar S, Silva-Velasco DL, Priviero F, Webb RC.   +3 more
europepmc   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

MiRNA-140-5p Modulates Cartilage Mechanical Environment by Preserving Surface Stress Homeostasis. [PDF]

Cartilage
Li B, Chen G, Han L, Li H, Zou N.
europepmc   +1 more source