Results 291 to 300 of about 123,069 (394)

Rac1 and Cdc42 but Not RhoA or Rho Kinase Activities Are Required for Neurite Outgrowth Induced by the Netrin-1 Receptor DCC (Deleted in Colorectal Cancer) in N1E-115 Neuroblastoma Cells [PDF]

, 2002
Xiaodong Li, Etienne Saint-Cyr-Proulx, Klaus Aktories, Nathalie Lamarche‐Vane   +3 more
openalex   +1 more source

The Bionic Interface: Considering the Material Mediated Electrical Stimulation of Stem Cells

Advanced Materials, Volume 38, Issue 2, 8 January 2026.
Electrical stimulation directs stem cell fate in tissue engineering. Cellular responses are influenced by membrane properties, intrinsic cell state, material charge‐transport characteristics, and the applied electrical signal. Additionally, a material’s ability to inject, store, and redistribute charge further modulates these responses.
Kaiwen Zhang, Daniel De Maria, Mercyjayapriya Jebakumar, James Collins, Kate E. Fox, Peter C. Sherrell, Amy Gelmi   +6 more
wiley   +1 more source

Ubiquitylation-dependent Rap2 activation regulates lamellipodia dynamics during cell migration. [PDF]

J Cell Sci
Neumann A, Sampath R, Mayerhofer E, Mikalayeva V, Skeberdis VA, Sarapinienė I, Prekeris R.   +6 more
europepmc   +1 more source

ARHGAP18 Downregulation by miR-200b Suppresses Metastasis of Triple-Negative Breast Cancer by Enhancing Activation of RhoA.

Cancer Research, 2017
Brock A. Humphries, Zhishan Wang, Yunfei Li, Jing-Ru Jhan, Yiguo Jiang, Chengfeng Yang   +5 more
semanticscholar   +1 more source

Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang, Pengfei Jiang, Joshua B Stein, Yannan Hou, Chaochen Zhou, Heemin Kang, Ki‐Bum Lee   +6 more
wiley   +1 more source

GLMP promotes EGFR-TKI resistance by activating autophagy and RhoA pathway in non-small cell lung cancer. [PDF]

NPJ Precis Oncol
Liang X, Xu J, Shu S, Lv W, Yin D, Miao S, Lu X, Zhang C, Liu X, Dai J, Li J, Wu W, Zhang E, Guo R.   +13 more
europepmc   +1 more source

LncRNA THUMPD3‐AS1 Regulates Behavioral and Synaptic Structural Abnormalities in Schizophrenia via miR‐485‐5p and ARHGAP8

Advanced Science, Volume 13, Issue 3, 14 January 2026.
Schizophrenia (SCZ) is linked to synaptic structural deficits driven by dysregulated noncoding RNAs. Using the novel ceRNAxis pipeline, THUMPD3‐AS1/miR‐485‐5p/ARHGAP8 is identified as a key regulator of actin cytoskeletal remodeling through noncanonical RhoB/C‐ROCK2 signaling. Modulating this axis ameliorates SCZ‐like phenotypes in mice and aligns with
Xiaojuan Gong, Lingxi Chen, Xin Guo, Anna Jiang, Yayi He, Chunxia Yan, Liang Ma, Jiayang Gao, Jinyu Zhang, Bao Zhang   +9 more
wiley   +1 more source

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

Advanced Science, Volume 13, Issue 3, 14 January 2026.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin, Yuxiao Zheng, Yu Zhong, Hongyan Wang   +3 more
wiley   +1 more source

TET1-Mediated DNA hydroxymethylation of KLF6 promotes LPS-induced pulmonary fibrosis by activating the S1PR3/RhoA/ROCK signaling pathway. [PDF]

Respir Res
Chen J, Chen L, Wang Z, Cao J, Yang H, Li J.   +5 more
europepmc   +1 more source

Brillouin Microscopy of Breast tumor Spheroids On‐a‐Chip: Mechanical and Transcriptional Responses to Microfluidic‐Induced Rapid Deformations

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Brillouin‐Raman Microspectroscopy on‐a‐Chip (BRmS) enables real‐time analysis of breast tumor spheroids in microfluidic channels. Following cyclical deformations, MCF10.DCIS.com spheroids are captured in recovery traps and imaged with BRmS. The applied deformations trigger a stiffening response marked by increased frequency shifts, elevation of the ...
Mona Makkieh, Alessandra Anna Passeri, Davide Lazzari, Stefano Marchesi, Andrea Disanza, Rafal Khaled Ahmad Salem, Francesco Bonacci, Camillo Mazzella, Emanuele Martini, Mattia Tonani, Leonardo Donati, Edoardo Bellini, Hind Abdo, Judith Pineau, Serena Magni, Fabrizio Orsenigo, Matthieu Piel, Daniele Fioretto, Sabata Martino, Maurizio Mattarelli, Giorgio Scita, Brenda J. Green, Silvia Caponi   +22 more
wiley   +1 more source