Results 321 to 330 of about 123,069 (394)

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer [PDF]

Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐Tai Lu, Alfred K. Lam, Nam‐Trung Nguyen   +5 more
openalex   +1 more source

Anti‐Neuroinflammation Activity of Essential Oils and Fatty Acids

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Neuroinflammation plays a pivotal role in the pathogenesis of neurodegenerative disorders, including Alzheimer's disease (AD) and Parkinson's disease (PD). Current pharmacological interventions, such as NSAIDs and corticosteroids, are limited by systemic toxicity and insufficient efficacy in targeting chronic neuroinflammatory processes.
Zelong Jin, Yige Song, Ahmed Attia Ahmed Abdelmoaty, Feng Lin, Jiujun Li, Xianyang Chen   +5 more
wiley   +1 more source

Endodermal cells use contact inhibition of locomotion to achieve uniform cell dispersal during zebrafish gastrulation. [PDF]

iScience
LaBelle J, Wyatt T, Ramirez J, Woo S.
europepmc   +1 more source

Madelung Disease of the Scrotal Region: A Case Report

IJU Case Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Introduction Madelung disease is a rare disorder characterized by symmetrical fat accumulation, typically around the neck, shoulders, and trunk. Case Presentation A 56‐year‐old man presented for 10‐month history of dysuria and painless swelling of the lower abdomen and scrotum.
Kazuki Kokura, Akihiro Kanematsu, Hideki Morisaki, Yasuhiro Shinkai, Takashi Yamasaki, Kenichiro Kawai, Masao Kakibuchi, Seiichi Hirota, Shingo Yamamoto   +8 more
wiley   +1 more source

Reduced RhoGDI2 Expression Disrupts Centrosome Functions and Promotes Mitotic Errors. [PDF]

Cells
Tripathi M, Garbacki N, Willems J, Cobraiville G, Fillet M, Colige A, Deroanne CF.   +6 more
europepmc   +1 more source

Shexiang Tongxin dropping pills ameliorate myocardial ischemia-reperfusion injury progression via the S1PR2/RhoA/ROCK pathway

Ying Sun, Boyang Jiao, Yizhou Liu, Ran Wang, Qiong Deng, David N. Criddle, Yulin Ouyang, Wei Wang, Xuegong Xu, Chun Li   +9 more
openalex   +1 more source

Myofibroblast‐Derived Extracellular Vesicles Drive Profibrotic Cascade Amplification in Pulmonary Fibrosis via the Nestin‐Rab7 Axis

Journal of Extracellular Vesicles, Volume 15, Issue 1, January 2026.
ABSTRACT Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease characterized by aberrant myofibroblast activation and excessive extracellular matrix deposition, with extracellular vesicles (EVs) playing a crucial role in this pathological process. We observed that EVs levels are significantly elevated in IPF and positively correlate with
Xiaofan Lai, Yong Xiao, Yingying Lin, Senyu Yao, Bin Wang, Hainan Chen, Tianxiang Lei, Shaojie Huang, Chenxing Lei, Qihao Zeng, Yuan Qiu, Hong Chen, Tao Wang, Jiancheng Wang, Andy Peng Xiang   +14 more
wiley   +1 more source

Direct crosstalk between GPCRs and ion channels via G proteins. [PDF]

Exp Mol Med
Kim SH, Kim J, So I, Lee HH.
europepmc   +1 more source

Reviewer #2 (Public review): Identification of novel microcephaly-linked protein ABBA that mediates cortical progenitor cell division and corticogenesis through NEDD9-RhoA

Aurelie Carabalona, Henna Kallo, Maryanne Gonzalez, Liliia Andriichuk, Ellinoora Elomaa, Florence Molinari, Christiana Fragkou, Pekka Lappalainen, Marja W Wessels, Juha Saarikangas, Claudio Rivera   +10 more
openalex   +1 more source

Spatial Transcriptional Heterogeneity in the Infarct Core and Its Surrounding Regions Targeting Piezo1 Signals in Rats With Myocardial Ischemia‐Reperfusion Injury

MedComm, Volume 7, Issue 1, January 2026.
We employed spatially resolved transcriptomics to visualize and molecularly characterize the spatial distribution of gene expression profiles in the rats’ left ventricles following MIR injury. Further experiments indicated that cardiogenic Piezo1‐mediated calcium overload exacerbates MIR through the activation of matrix metalloproteinase 2‐ryanodine ...
Zhen Li, Fan Jiang, Yan Chen, Zhixiao Li, Yanqiong Wu, Zhigang He, Duozhi Wu, Hongbing Xiang   +7 more
wiley   +1 more source