Results 371 to 380 of about 123,069 (394)

Targeting by myosin phosphatase‐RhoA interacting protein mediates RhoA/ROCK regulation of myosin phosphatase

Journal of Cellular Biochemistry, 2007
AbstractVascular smooth muscle cell contractile state is the primary determinant of blood vessel tone. Vascular smooth muscle cell contractility is directly related to the phosphorylation of myosin light chains (MLCs), which in turn is tightly regulated by the opposing activities of myosin light chain kinase (MLCK) and myosin phosphatase.
Nadeene, Riddick, Ken-Ichi, Ohtani, Howard K, Surks   +2 more
openaire   +2 more sources

Inactivation of RhoA for Hypertension Treatment Through the TRPV4–RhoA–RhoGDI1 Axis

Circulation
BACKGROUND: The RhoA (Ras homolog family member A) signaling pathway is pivotal in regulating vascular smooth muscle cells (VSMCs) function and blood pressure homeostasis. Current inhibitors of the RhoA signaling pathway are limited in hypertension treatment, suffering from poor efficacy, insufficient specificity, and ...
Jiawen Wang, Zhen Yuan, Na Yu, Qian Jiao, Honglei Zhou, Wenjie Liao, Jiwei Shan, Shanshan Ruan, Yi Zhao, Ya Mo, Luyao Qi, Tiejun Li, Jianjun Fu, Bowen Ke, Yufang Xu, Xuhong Qian, Jian Zhang, Zhenjiang Zhao, Shiliang Li, Rui Wang, Honglin Li   +20 more
openaire   +1 more source

RhoA

AfCS-Nature Molecule Pages, 2009
Jun Miyoshi, Yoshimi Takai
openaire   +1 more source

RhoA

2016
Jose L. Orgaz, Victoria Sanz-Moreno
openaire   +1 more source

RhoA-p160Rock communication

GBM Annual Fall meeting M�nster 2004, 2004
Radovan Dvorsky, Lars Blumenstein, Patricia Stege, Mohhamad Reza Ahmadian   +3 more
openaire   +1 more source

Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway

Nature Materials, 2020
Antonios Chronopoulos, Stephen D Thorpe, Dariusz Lachowski   +2 more
exaly  

Ligand Diffusion Enables Force‐Independent Cell Adhesion via Activating α5β1 Integrin and Initiating Rac and RhoA Signaling

Advanced Materials, 2020
Leixiao Yu, Wenyan Xie, Luis Cuellar Camacho   +2 more
exaly  

Lovastatin Inhibits RhoA Expression and Increases Rac1/RhoA Ratio in Alveolar Macrophages

Chest, 2013
Kunihiko Hiraiwa, Stephan F. van Eeden
openaire   +1 more source

p190A inactivating mutations cause aberrant RhoA activation and promote malignant transformation via the Hippo-YAP pathway in endometrial cancer

Signal Transduction and Targeted Therapy, 2020
Shuang-Di Li, Kun Gao, Xiaoping Wan
exaly  

Spatiotemporal dynamics of RhoA activity in migrating cells

Nature, 2006
Olivier Pertz, Louis Hodgson, Klaus M Hahn   +2 more
exaly