Results 151 to 160 of about 2,526 (217)

Asymmetry in Hydrophobicity Induces Electric Potential in Non‐Charged Biomolecular Condensates

open access: yesAdvanced Science, EarlyView.
 Non‐charged biomolecular condensates can encode electric potential gradient through defining asymmetry in environmental hydrophobicity. ABSTRACT The capacity of biomolecular condensates to establish and modulate electrochemical equilibria is emerging as an important functioning mechanism in cellular biochemistry.
Leshan Yang   +3 more
wiley   +1 more source

Polarography of Rhodamine B

open access: yesNippon kagaku zassi, 1963
Hiromu IMAI, Kiyoshi KUZUTANI
openaire   +2 more sources

Bioorthogonal Activation of Deep Red Photoredox Catalysis Inducing Pyroptosis. [PDF]

open access: yesJ Am Chem Soc
Kim J   +7 more
europepmc   +1 more source

Cell Cycle‐Specific Regulation of Centrosome Clustering Dynamics in Cancer Cells by the Multifunctional Kinesin HSET

open access: yesAdvanced Science, EarlyView.
CDK5RAP2 associates with the kinesin HSET and forms co‐condensates. HSET motors drive the directional transport of CDK5RAP2 condensates toward microtubule minus ends. During mitosis, HSET self‐assembly further stabilizes clustered centrosomes, thereby enabling pseudo‐bipolar spindle formation in cancer cells with supernumerary centrosomes. Upon mitotic
Po‐Pang Chen   +11 more
wiley   +1 more source

Deep Learning Prediction of Surface Roughness in Multi‐Stage Microneedle Fabrication: A Long Short‐Term Memory‐Recurrent Neural Network Approach

open access: yesAdvanced Intelligent Discovery, EarlyView.
A sequential deep learning framework is developed to model surface roughness progression in multi‐stage microneedle fabrication. Using real‐world experimental data from 3D printing, molding, and casting stages, an long short‐term memory‐based recurrent neural network captures the cumulative influence of geometric parameters and intermediate outputs ...
Abdollah Ahmadpour   +5 more
wiley   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng   +4 more
wiley   +1 more source

Sequence‐Modulated Active Tripeptide Condensates for Tandem Catalysis

open access: yesAngewandte Chemie, EarlyView.
Sequence‐modulated tripeptide coacervates mimic biomolecular condensates with controllable, enzyme‐regulated phase separation. They co‐sequester hydrophobic active species and hydrophilic enzymes, enabling tandem catalysis in aqueous media. Incorporated into artificial cells, they function as adaptive sub‐organelles, orchestrating compartmentalized ...
Hao Han   +7 more
wiley   +2 more sources

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