Results 161 to 170 of about 2,526 (217)

Bistable Dual‐Responsive Azobenzene‐co‐PNIPAM Soft Microactuators via Two‐Photon Direct Laser Writing

open access: yesAdvanced Intelligent Systems, EarlyView.
This work shows the successful integration of intrinsic bistability into thermoresponsive soft microactuators, fabricated by two‐photon polymerization utilizing the (E)–(Z)‐isomerization of azobenzenes. The bistable behavior accounts for a reversible volume change of Azo_pNIPAM microactuators initiated by light irradiation, at constant ambient ...
Chantal Barwig   +13 more
wiley   +1 more source

Chemical Proteomics Identifies Ketogenesis‐Mediated Cysteine Modifications Regulating Redox Function

open access: yesAngewandte Chemie, EarlyView.
Herein, we report ketone body induce cysteine modifications beyond lysine acylation, as revealed by integrating chemical proteomics with open‐search methods. Among the modifications, cysteine crotonation (Ccr) was chemically validated by endogenous peptide‐based co‐elution assays.
Yuan‐Fei Zhou   +8 more
wiley   +2 more sources

Correlations Between Osteocyte Lacuno‐Canalicular Network and Material Characteristics in Healthy and Mechanically Stimulated Murine Tibiae

open access: yesAdvanced NanoBiomed Research, EarlyView.
This article reveals how calcium content, mineral nanostructure, and lacuno‐canalicular network (LCN) organization interact to shape bone heterogeneity in mouse tibiae. Advanced multimodal imaging uncovers that mechanical loading promotes mature mineral structures even in low‐calcium regions, highlighting LCN‐driven mineralization and offering new ...
Victoria Schemenz   +10 more
wiley   +1 more source

From Covalent Traps to Fluorescent Beacons: The Expanding Arsenal of Chemical Probes for Studying Ubiquitin and Ubiquitin‐Like Proteins

open access: yesAngewandte Chemie, EarlyView.
A large variety of chemistry‐based ubiquitin probes have been developed. ABSTRACT Ubiquitin (Ub) and ubiquitin‐like proteins (Ubls) orchestrate diverse cellular processes through reversible post‐translational modification of target proteins. Their conjugation is governed by a cascade of E1 activating, E2 conjugating, and E3 ligating enzymes, while ...
Saibal Chanda, Wenshe Ray Liu
wiley   +1 more source

Harnessing Methyltransferase‐Guided Targeting for Sequence‐Specific Proximity Labeling of DNA

open access: yesAngewandte Chemie, EarlyView.
A novel methyltransferase‐mediated approach leveraging rationally designed S‐adenosyl‐L‐methionine (SAM) analogues was developed to achieve sequence‐specific DNA labeling but in proximity to the natural transfer site, addressing key limitations of previously established methods, including ligand instability and methylation‐sensitive labeling.
Xiong Chen   +8 more
wiley   +1 more source

Hybrid of Indolizine and Merocyanine-A New Class of Organelle-Specific Dyes. [PDF]

open access: yesAngew Chem Int Ed Engl
Badaro JSA   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy