Results 181 to 190 of about 2,906 (266)
Angewandte Chemie, EarlyView.Fluorescence image of the coronal slice of mouse brain where multiple neurochemicals have been measured in vivo with a nanodialysis platform coupled to CE‐MS to reveal strong millimeter‐scale spatial chemical gradients. Formation and maintenance of such local chemical compartments in the otherwise diffusion‐homogeneous cortex indicates strong ...
Weihua Shi +5 more
wiley +2 more sources
Xanthene-Based Dyes for Photoacoustic Imaging and their Use as Analyte-Responsive Probes. [PDF]
ChemistryBrøndsted F, Stains CI.
europepmc +1 more source
Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis
Advanced NanoBiomed Research, EarlyView.Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia +10 more
wiley +1 more source
A Lipid‐Conjugation Strategy for Intracellular Reactive Oxygen Species Control in Hepatic Cells
Angewandte Chemie, EarlyView.A lipid conjugation strategy anchors a manganese Salen complex within phospholipid membranes, yielding stable, catalytically active liposomes. These lipid–metal assemblies efficiently degrade reactive oxygen species (ROS) and enable intracellular redox control in steatotic HepaRG cells, offering a precise route to biomimetic antioxidant design ...
Olav Vestrheim +7 more
wiley +2 more sources
Blinking characteristics of organic fluorophores for blink-based multiplexing. [PDF]
Commun ChemSeabury AG +5 more
europepmc +1 more source
Angewandte Chemie, EarlyView.Die Kontrolle biologischer Systeme mit organischen Chromophoren hat sich zu einer vielversprechenden Strategie entwickelt und findet Anwendung von der chemischen Biologie bis hin zur Medizin. Die Komplexität von In‐vivo‐Systemen lässt sich jedoch nicht mit nur einer einzigen Lichtwellenlänge adäquat abbilden.
Nadja A. Simeth
wiley +1 more source
Angewandte Chemie, EarlyView.Red‐emissive carbon dots (R‐CDs) exhibiting aggregation‐induced emission (AIE) and aggregation‐caused quenching (ACQ) effects are synthesized from citric acid and urea. They display weak blue fluorescence in water but strong red emission in DMF due to aggregation.
Jiafeng Wan +11 more
wiley +2 more sources
Silicon Rhodamine-Based Fluorescence Lifetime Probe for Dynamics Mapping Lysosomal Oxidative Stress. [PDF]
Chem Biomed ImagingXu Q +9 more
europepmc +1 more source
Mitochondria‐Damaging Self‐Reporting Probe for Cancer Therapy
Angewandte Chemie, EarlyView.We developed a class of self‐reporting cationic chemotherapeutic probes that selectively induce mitochondrial damage and apoptosis in cancer cells. Their unique mitochondria‐to‐nucleus fluorescence migration enables real‐time visualization of the therapeutic process. ABSTRACT Mitochondrial damage induced by chemotherapeutic agents through disruption of
Hai Xu +10 more
wiley +2 more sources
Angewandte Chemie, EarlyView.Color‐pure all‐organic emitters, i.e., with narrow spectral characteristics, are intensively studied for high‐definition organic LEDs and multi‐color bioimaging. In order to guide targeted materials design, this educative review discusses spectral characteristics, proper definitions and units, and the physical basis of spectral broadening, to distill ...
Johannes Gierschner +6 more
wiley +2 more sources