Results 11 to 20 of about 2,526 (217)

Gentle Rhodamines for Live-Cell Fluorescence Microscopy [PDF]

ACS Central Science
Tianyan Liu, Julian Kompa, Jing Ling, Nicolas Lardon, Yuan Zhang, Jingting Chen, Luc Reymond, Peng Chen, Mai Tran, Zhongtian Yang, Haolin Zhang, Yitong Liu, Stefan Pitsch, Peng Zou, Lu Wang, Kai Johnsson, Zhixing Chen   +16 more
doaj   +2 more sources

A diversity-oriented rhodamine library for wide-spectrum bactericidal agents with low inducible resistance against resistant pathogens

Nature Communications, 2019
Preparation of xanthene-containing compounds has been limited due to structural bias existing methods pose. Here, the authors developed a mild, diversity-oriented method for rhodamines synthesis, leading to the finding of compounds with antibacterial ...
Xiao Luo, Liujia Qian, Yansheng Xiao, Yao Tang, Yang Zhao, Xia Wang, Luyan Gu, Zuhai Lei, Jianming Bao, Jiahui Wu, Tingting He, Fupin Hu, Jing Zheng, Honglin Li, Weiping Zhu, Lei Shao, Xiaojing Dong, Daijie Chen, Xuhong Qian, Youjun Yang   +19 more
doaj   +1 more source

Study of internalization and viability of multimodal nanoparticles for labeling of human umbilical cord mesenchymal stem cells [PDF]

Einstein (São Paulo), 2012
OBJECTIVE: To analyze multimodal magnetic nanoparticles-Rhodamine B in culture media for cell labeling, and to establish a study of multimodal magnetic nanoparticles-Rhodamine B detection at labeled cells evaluating they viability at concentrations of ...
Liza Aya Mabuchi Miyaki, Tatiana Tais Sibov, Lorena Favaro Pavon, Javier Bustamante Mamani, Lionel Fernel Gamarra   +4 more
doaj   +1 more source

An Optofluidic Temperature Probe

Sensors, 2013
We report the application of a microfluidic device for semi-contact temperature measurement in picoliter volumes of aqueous media. Our device, a freely positionable multifunctional pipette, operates by a hydrodynamic confinement principle, i.e., by ...
Aldo Jesorka, Gavin David Michael Jeffries, Alar Ainla, Ilona Węgrzyn   +3 more
doaj   +1 more source

Photoactivation of silicon rhodamines via a light-induced protonation

Nature Communications, 2019
Activatable fluorophores are of interest for a wide range of applications but the need for caging groups complicates their development and application.
Michelle S. Frei, Philipp Hoess, Marko Lampe, Bianca Nijmeijer, Moritz Kueblbeck, Jan Ellenberg, Hubert Wadepohl, Jonas Ries, Stefan Pitsch, Luc Reymond, Kai Johnsson   +10 more
doaj   +1 more source

Asymmetric and Reduced Xanthene Fluorophores: Synthesis, Photochemical Properties, and Application to Activatable Fluorescent Probes for Detection of Nitroreductase

Molecules, 2019
Xanthene fluorophores, including fluorescein, rhodol, and rhodamines, are representative classes of fluorescent probes that have been applied in the detection and visualization of biomolecules.
Kunal N. More, Tae-Hwan Lim, Julie Kang, Hwayoung Yun, Sung-Tae Yee, Dong-Jo Chang   +5 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A General Strategy to Fine‐Tune Group 14 Rhodamines for Ultrahigh Signal‐to‐Noise Ratio Labeling In Vivo by Nano‐Aggregation

Aggregate
Ultrahigh signal‐to‐noise ratio (SNR) labeling enables precise visualization of biological structures in vivo. We boosted fluorogenicity in group‐14‐rhodamines by comprehensively manipulating their dynamics in physical (aggregate/monomer, KA/M) and ...
Ning Wang, Ting Wang, Mengting Fan, Chen Li, Yue Tian, Xiaoyan Cui   +5 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source