Results 41 to 50 of about 178 (132)
An Expanded Mechanism for Rhodanese Catalysis
Abstract The kinetic behavior of rhodanese (thiosulfate:cyanide sulfurtransferase, EC 2.8.1.1) was investigated at pH values from 5.0 to 10.8. The binding of thiosulfate was shown to be dependent upon a pK' of 9.9, with the protonated enzyme binding the substrate much more strongly than the deprotonated form. An enzymic nucleophile displaces sulfite to
P, Schlesinger, J, Westley
openaire +2 more sources
Plastid Engineering for Photosynthesis‐Driven Synthesis of Hyaluronic Acid in Tobacco
ABSTRACT Hyaluronic acid (HA) is a glycosaminoglycan composed of alternating units of N‐acetylglucosamine and glucuronic acid. High moisture retention, viscoelasticity and biocompatibility are unique features that make HA polymers attractive compounds for medical applications and aesthetic purposes.
Amanda Lopes +10 more
wiley +1 more source
SUMMARY Omics‐driven approaches can capture systemic plant responses to pathogens. While transcriptomics is a mainstay, it alone cannot capture post‐translational modifications or protein abundance. Because of this, we employed multi‐proteomics to compare the proteome, phosphoproteome, and acetylome of two rice genotypes differing in resistance to ...
Priscila A Auler +5 more
wiley +1 more source
Bovine mitochondrial rhodanese is a phosphoprotein
The mitochondrial sulfurtransferase, rhodanese, has been analyzed for phosphate content. Significant amounts of protein-bound phosphate (30-40%) were measured in the six rhodanese preparations examined. Chromatographic experiments followed by phosphate analyses done on two of the preparations indicated that rhodanese A and rhodanese B, two enzyme forms
K, Ogata, X, Dai, M, Volini
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ABSTRACT Chemical, biological, radiological, and nuclear (CBRN) incidents present escalating challenges, particularly in geopolitically unstable regions such as the Middle East and North Africa. Despite advances, gaps exist regarding optimal decontamination protocols and agent‐specific antidote selection algorithms, exacerbated by variable operational ...
Hassan Farhat +6 more
wiley +1 more source
Supersulfide biology and translational medicine for disease control
Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu +5 more
wiley +1 more source
Gut microbes can enhance the ability of hosts to consume secondary plant compounds and, therefore, expand the dietary niche breadth of mammalian herbivores.
Lifeng Zhu +7 more
doaj +1 more source
Here, we experimentally expand understanding of the reactions and enzymes involved in Acidithiobacillus thiooxidans ATCC 19377 S0 and S2O32- metabolism by developing models that integrate gene expression analyzed by RNA-Seq, solution sulfur speciation ...
David Camacho +10 more
doaj +1 more source
Sorghum Poisoning in Livestock: Mechanisms, Risks, and Sustainable Mitigation Strategies
Sorghum (Sorghum bicolor L. Moench) is a drought‐tolerant crop grown in both arid and semiarid regions and serves as both food and fodder. Under environmental stresses, sorghum accumulates cyanogenic glucosides, especially dhurrin. Through ingestion, dhurrin is hydrolyzed into a toxic element called hydrogen cyanide (HCN).
Mahmud Sindid Ikram +2 more
wiley +1 more source
The developed graphene‐assisted plasmonic nanocoral platform enables sensitive, label‐free surface‐enhanced Raman scattering analysis of salivary metabolites for head and neck cancer (HNC) detection. When combined with machine learning classification and nonnegative least squares‐based spectral deconvolution, this approach achieves 98% diagnostic ...
Hyo Jeong Seo +11 more
wiley +1 more source

