Results 231 to 240 of about 53,119 (305)

Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations

Advanced Science, EarlyView.
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford, Matthew Tamasi, Elena Di Mare, Adam J. Gormley   +3 more
wiley   +1 more source

Polymer-Grafted Cu(II) Metal-Organic Polyhedra as Scalable, Melt-Processable Porous Materials. [PDF]

Adv Sci (Weinh)
Cortés-Martínez A, Sánchez-Férez F, Suárez Del Pino JA, Royuela S, Zamora F, Maspoch D, Carné-Sánchez A.   +6 more
europepmc   +1 more source

Targeted Multifunctional Fluorine‐Rich Copolymer Coating Design for Ambient‐Stable Prelithiated SiOC Anodes

Advanced Science, EarlyView.
A fluorine‐rich acrylate copolymer, poly (tridecafluorooctyl methacrylate‐co‐methyl methacrylate) (PFMMA), is introduced as a multifunctional protective coating to stabilize the prelithiated SiOC electrodes in humid conditions and preserve unimpeded interfacial ion/charge transport during redox reactions.
Rong Chen, Yixuan Fan, Congcong Zhang, Yinan Liu, Yun Zheng, Ruifeng Zheng, Yingying Shen, Pingshan Jia, Luojiang Zhang, Yongbing Tang, Huaiyu Shao   +10 more
wiley   +1 more source

Enantioselective Synthesis of Axially Chiral Spiro[3.3]heptanes by Site-Selective C-H Functionalization. [PDF]

ACS Catal
Ly D, Chen Z, Musaev DG, Davies HML.
europepmc   +1 more source

Relaxor Ferroelectricity Enables Enhanced Thermoelectric Performance in In2Se3‐Alloyed GeTe

Advanced Science, EarlyView.
A non‐equimolar In3+/Se2− alloying strategy creates Ge vacancies in GeTe, inducing relaxor ferroelectricity that broadens the low thermal conductivity window. Simultaneously, cubic phase stabilization broadens optimal electrical transport, achieving an average zT > 1.0 over 330–625 K.
Yuting Zhang, Yang Li, Jianguo Chen, Kai Guo, Jun Luo, Jiye Zhang   +5 more
wiley   +1 more source

Hyperpolarization of Pyridine ¹⁵N-Oxide Molecular Probes Enabled by Parahydrogen. [PDF]

Angew Chem Int Ed Engl
Mei R, Fries LM, Rodriguez GG, von Petersdorff-Campen C, May LK, Matz JF, Korchak S, Daher G, Glöggler S.   +8 more
europepmc   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Unmasking true confinement effects: ultrahigh linear selectivity and chain-length oscillatory behavior in zeolite-encapsulated rhodium hydroformylation. [PDF]

Natl Sci Rev
Yan T, Zhang X, Song G, Zhou Z, Hou H, Xie Q, He H, Tong X, Chang H, Liu Z, Zheng A, Cao Z, He P.   +12 more
europepmc   +1 more source

Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform

Advanced Science, EarlyView.
Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao, Cang‐Man Zhang, Ru‐Jie Yang, Min Ren, Zhuo‐Ling Zhong, Kang‐Hui Wang, Rui‐Xue Hu, Jia‐Yue Liu, Jun‐Yi Zhou, Hou‐Kai Li, Jian‐Bo Wan   +10 more
wiley   +1 more source

Dental Implant Displacement Into the Maxillary Sinus Ostium: A Case Report of Customized Surgical Management. [PDF]

Cureus
Kasapoglu MB, Sahabettinoglu A, Atalay B.   +2 more
europepmc   +1 more source