Results 51 to 60 of about 996 (141)

Engineered Phenylalanine Ammonia‐Lyases for the Enantioselective Synthesis of Aspartic Acid Derivatives

Angewandte Chemie, Volume 136, Issue 31, July 29, 2024.
A structure‐based engineering of phenylalanine ammonia‐lyase from Planctomyces brasiliensis (PbPAL) is conducted for preparative‐scale enantioselective hydroaminations of previously inaccessible yet synthetically useful substrates, such as amide‐ and ester‐containing fumaric acid derivatives.
Ivan Buslov, Sarah Desmons, Yoan Duhoo, Xile Hu   +3 more
wiley   +2 more sources

Four inducible promoters for controlled gene expression in the oleaginous yeast Rhodotorula toruloides

Frontiers in Microbiology, 2016
Rhodotorula (Rhodosporidium) toruloides is an oleaginous yeast with great biotechnological potential, capable of accumulating lipid up to 70 % of its dry biomass, and of carotenoid biosynthesis.
Alexander Michael Bedford Johns, John Love, Stephen John Aves   +2 more
doaj   +1 more source

Suppressing Glycerol‐3‐phosphate Phosphatase and Enhancing Glycerol‐3‐Phosphate Shuttle Flux Crucial for High‐Efficiency Fatty Acid Production in the Fast‐Growing Oleaginous Schizochytrium

Advanced Science, Volume 12, Issue 45, December 4, 2025.
This study establishes an efficient oleaginous heterotrophic microalga, Schizochytrium, through chassis optimization and metabolic engineering, significantly enhancing fatty acid titers and productivities. It also identifies a regulatory mechanism that coordinates biomass and lipid synthesis, providing a rational target for metabolic pathway rewiring ...
Fangzhong Wang, Weijia Jin, Tiantian Wang, Junkai Ji, Kun Cao, Jianqiang Li, Lei Chen, Weiwen Zhang   +7 more
wiley   +1 more source

Engineering Strategies for Fungal Cell Disruption in Biotechnological Applications

Engineering in Life Sciences, Volume 25, Issue 12, December 2025.
ABSTRACT Fungal cell disruption plays a critical role in unlocking a wide range of high‐value intracellular products such as lipids, proteins, pigments, and bioactive compounds. However, lysing fungal cells is far more challenging than breaking bacterial or algal cells due to their robust and highly structured cell walls.
Bhagyeshri Ulhas Mantri, Maliheh Vahidinasab, Sonja Berensmeier   +2 more
wiley   +1 more source

Brazilian Biomes as Promising Resources of Rhodotorula Yeasts for the Biotechnological Production of Carotenoids

Chemistry &Biodiversity, Volume 22, Issue 10, October 2025.
ABSTRACT Yeasts belonging to the genus Rhodotorula are capable of synthesizing carotenoids, such as β‐carotene, γ‐carotene, torulene, torularodine, and astaxanthin. These carotenoids have been shown to offer health benefits to humans, such as immune system strengthening and a reduced risk of chronic degenerative diseases.
David Cristian Rodrigues Lucas, Renan Campos Chisté   +1 more
wiley   +1 more source

Optimization of in Vitro Carotenoid Production by Rhodotorula Toruloides

Chemical Engineering Transactions
Carotenoids are widely researched due to their correlation with the mitigation of severe illnesses such as cancer, cardiovascular disease, and macular degeneration, which points out the critical significance of natural pigments.
Thai M. Nguyen, Trinh T.L. Nguyen, Tu T. Nguyen, Nhat N.N. Vo, Nhan T. Vo, Yen T.N. Nguyen   +5 more
doaj   +1 more source

Analysis of Genotypic Variations in the Anthocyanin Biosynthetic Pathway in Potatoes

Plant Direct, Volume 9, Issue 9, September 2025.
ABSTRACT Anthocyanins are pigments that contribute to plant defense and adaptation to environmental stresses. Given their antioxidant properties and positive impacts on human health, enhancing anthocyanin biosynthesis in plants holds significant economic importance.
Chae‐Min Lee, Seung Yong Shin, Su‐Jin Park, Ji‐Sun Park, Changsoo Kim, Hyun‐Soon Kim, Hyo‐Jun Lee   +6 more
wiley   +1 more source

Multi‐Omics Analysis Reveals the Selenium‐Regulatory Metabolism in Rare Yeast Kazachstania unispora KU2

Food Frontiers, Volume 6, Issue 4, Page 1913-1925, July 2025.
The mechanism of selenium‐regulatory unique metabolism in rare yeast Kazachstania unispora KU2 was explored via joint analysis of genomics, transcriptomics, and metabolomics. Arginine biosynthesis, glutathione metabolism, selenocompound metabolism, and TCA cycle were significantly associated with the selenium enrichment process in Kazachstania unispora
Furong Wang, Jiadi Zhang, Yilei Xiao, Zeyu Hu, Xian Wang, Yuqi Gao, Kewei Feng, Yahong Yuan, Tianli Yue   +8 more
wiley   +1 more source

Lipid production from Jerusalem artichoke by Rhodosporidium toruloides Y4

Journal of Industrial Microbiology & Biotechnology, 2010
Jerusalem artichoke (JA) is a perennial herbaceous plant widely available as non-grain raw material. Microbial lipid has been suggested as a potential feedstock for large scale biodiesel production. This paper describes lipid production using JA tuber processed by oleaginous yeast Rhodosporidium toruloides Y4. Batch and fed-batch modes were tested with
Xin, Zhao, Siguo, Wu, Cuimin, Hu, Qian, Wang, Yanyan, Hua, Zongbao K, Zhao   +5 more
openaire   +2 more sources

Exploring the potential of Rhodosporidium toruloides in biomanufacturing: a comprehensive review

Frontiers in Synthetic Biology
Rhodosporidium toruloides is an emerging non-conventional yeast host gaining significant attention in synthetic biology and metabolic engineering due to its innate ability to accumulate lipids, produce carotenoids, and utilize diverse carbon sources ...
Shubhasish Goswami, Blake A. Simmons, Blake A. Simmons, Taek Soon Lee, Taek Soon Lee   +4 more
doaj   +1 more source