Results 61 to 70 of about 265,325 (306)

Arrhythmia-Induced Cardiomyopathy in Atrial Fibrillation: Pathogenesis, Diagnosis, and Treatment

Life
Arrhythmia-induced cardiomyopathy (AIC) represents a potentially reversible form of LV dysfunction in which sustained atrial fibrillation (AF) and irregular, often rapid, ventricular activation drive maladaptive electrical, structural, and metabolic ...
Paschalis Karakasis, Panagiotis Theofilis, Panayotis K. Vlachakis, Anastasios Apostolos, Nikolaos Ktenopoulos, Konstantinos Grigoriou, Dimitrios Patoulias, Antonios P. Antoniadis, Nikolaos Fragakis   +8 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Controlling Trajectories with OneButton and Rhythm

Proceedings of the 2024 International Conference on Advanced Visual Interfaces
We demonstrate two-dimensional navigation with velocity control on a single button. Users can vary the speed of the controlled object by rhythm tapping, and can control direction by pressing and tilting, releasing the button once the desired rotation is achieved. Feedback is multisensory. Tactile pulses are being delivered at 30-degree intervals during
Alessio Bellino, Davide Rocchesso
openaire   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

What is the Effect of Social Rhythm Disrupting Events on Mood in Individuals with Bipolar Disorder? [PDF]

, 2013
The social zeitgeber hypothesis suggests that life events have the capacity to lead to the onset of affective episodes in those vulnerable to bipolar disorder via biological and social rhythm disruption. However, few studies have systematically evaluated
Levenson, Jessica
core  

Kuwait Atrial Fibrillation Management Analysis—Insights From a Tertiary Center in Kuwait

Journal of Arrhythmia
Background Real‐world data on atrial fibrillation (AF) contemporary management from the Gulf region are scarce and nonexistent from Kuwait. Despite recent guideline updates favoring early rhythm control, clinical characteristics, treatment strategies ...
S. AlKharji, S. A. Almoosawy, J. AlBalool, E. Shenouda   +3 more
doaj   +1 more source

Combination of early rhythm control and healthy lifestyle on the risk of stroke in elderly patients with new-onset atrial fibrillation: a nationwide population-based cohort study

Frontiers in Cardiovascular Medicine
BackgroundThe impact of early rhythm control (ERC) combined with healthy lifestyle (HLS) on the risk of ischemic stroke in elderly patients with atrial fibrillation (AF) remains unaddressed.ObjectiveTo evaluate the impact of combined ERC and HLS on the ...
Woo-Hyun Lim, Woo-Hyun Lim, So-Ryoung Lee, So-Ryoung Lee, Eue-Keun Choi, Eue-Keun Choi, Seung-Woo Lee, Kyung-Do Han, Seil Oh, Seil Oh, Gregory Y. H. Lip, Gregory Y. H. Lip, Gregory Y. H. Lip   +12 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Time-delayed feedback control in astrodynamics

, 2009
In this paper we present time-delayed feedback control (TDFC) for the purpose of autonomously driving trajectories of nonlinear systems into periodic orbits.
Biggs, James, BIGGS, JAMES DOUGLAS, McInnes, Colin, Biggs, James D., McInnes, Colin R.   +4 more
core   +1 more source

Associations of Sleep and Shift Work With Osteoarthritis Risk

Arthritis Care &Research, EarlyView.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source