Results 101 to 110 of about 69,474 (260)
Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia
The poor outcomes in infant acute lymphoblastic leukemia (ALL) necessitate new treatments. Here we discover that EIF4E protein is elevated in most cases of infant ALL and test EIF4E targeting by the repurposed antiviral agent ribavirin, which has ...
K. Urtishak+24 more
semanticscholar +1 more source
EFFECT OF RIBAVIRIN ON VIRAL HEPATITIS IN LABORATORY ANIMALS [PDF]
Robert W. Sidwell+3 more
openalex +1 more source
Treatment with polyethylene glycol-modified interferon alfa-2a (peginterferon) alone produces significantly higher sustained antiviral responses than treatment with interferon alfa-2a alone in patients with chronic hepatitis C virus (HCV) infection.
Francisco Bosques-Padilla, MD+7 more
doaj
IntroductionSignificant teratogenic effects have been demonstrated in all animal species exposed to ribavirin. Ribavirin is prescribed for chronic hepatitis C and is contraindicated in women who are pregnant and in the male sexual partners of women who ...
S. Sinclair+5 more
semanticscholar +1 more source
Modeling Ribavirin‐Induced Anemia in Patients with Chronic Hepatitis C Virus
Ribavirin remains an important component of hepatitis C treatment in certain clinical scenarios, but it causes hemolytic anemia. A quantitative understanding of the ribavirin exposure‐anemia relationship is important in dose individualization ...
LS Wu+4 more
doaj +1 more source
Effects of ribavirin on the development of the Friend leukemia [PDF]
Uta Opitz, Hans Seidel, G. Streissle
openalex +1 more source
Background/Purpose: The major dose-limiting toxicity of ribavirin is hemolytic anemia. We investigated the incidence, risk factors and impact on virological response of anemia in chronic hepatitis C genotype 2 patients receiving sofosbuvir plus ribavirin
Chi-Ching Chen+10 more
doaj
Background Globally, 80 million people are suffering from chronic Hepatitis C virus (HCV) infection. Sofosbuvir ribavirin-based anti-HCV therapy is associated with anemia and other adverse effects.
Sameen Amjed+6 more
doaj +1 more source
Effect of Ribavirin and immune serum on Junin virus-infected primates [PDF]
Mercedes Weissenbacher+5 more
openalex +1 more source
EFFECT OF RIBAVIRIN ON VIRAL TRANSCRIPTION [PDF]
Philip Toltzis+3 more
openalex +1 more source