Results 21 to 30 of about 45,850 (213)

Drug-Drug Interactions Among Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) Medications [PDF]

, 2015
One-fourth of individuals diagnosed with the human immunodeficiency virus concomitantly have the hepatitis C virus infection. Since the discovery of highly active antiretroviral therapy, liver complications have become the leading cause of morbidity and ...
Gandhi, Mona A., Kaur, Kirpal, Slish, Judianne   +2 more
core   +2 more sources

Effects of Host and virus related factors on Interferon-α+ribavirin and Pegylated-interferon+ribavirin treatment outcomes in Chronic Hepatitis C patients

Virology Journal, 2011
Background Current standard therapy commonly followed for chronic Hepatitis C Virus (HCV) in Pakistan is interferon alpha plus ribavirin combination therapy (IFN α/ribavirin) and pegylated interferon plus ribavirin (PegIFN/ribavirin).
Saleem Sana, Liaqat Ali, Rehman Irshad-ur, Afzal Samia, Butt Sadia, Hussain Abrar, Zafar Shamail, Idrees Muhammad, Akram Madiha, Ali Muhammad, Butt Azeem   +10 more
doaj   +1 more source

Impact of safety-related dose reductions or discontinuations on sustained virologic response in HCV-infected patients: Results from the GUARD-C Cohort [PDF]

, 2016
BACKGROUND: Despite the introduction of direct-acting antiviral agents for chronic hepatitis C virus (HCV) infection, peginterferon alfa/ribavirin remains relevant in many resource-constrained settings.
Abbas, Zaigham, Abdou, Ahmed Mohamed Saleh, Abou Rached, Antoine, Acalovschi, Monica, Afredj, Nawel, Ahlers, Silke, Ahmetagic, Sead, Ahn, Sang Hoon, Aissaoui, Magda, Akriviades, Euaggelos, Al Ghandoor, Zuhal, Al Gharabally, Abeer, Al Qameesh, Jihad, Alavian, Seyed Moayed, Alberto, Sara, Aleixo, Maria Jo\ue3o, Amedea, Alessandri, Amoroso, Pietro, Ancuta, Ioan, Andreica, Vasile, Andreoni, Massimo, Arama, Victoria, Ascione, Antonio, Askar, Haifa, Assene, Collins, Attili, Adolfo Francesco, Augustyniak, Krystyna, Baka Cwierz, Barbara, Bakalos, Georgios, Bandiera, Franco, Banyai, Tivadar, Basho, Jovan, Bassi, Paolo, Bastens, Boris, Bellantani, Stefano, Bellati, Giorgio, Berak, Hanna, Bevanda, Milenko, Bhalla, Ajay, Biglino, Alberto, Bocakova, Jana, Bourgeois, Stefan, Brixko, Christian, Brunetto, Maurizia, Bruno, Savino, Bunganic, Ivan, Calkic, Lejla, Caruntu, Florin, Casinelli, Katia, Castellacci, Roberto, Castelli, Francesco, Cattelan, Anna Maria, Chiriaco, Piergiorgio, Cijevschi, Cristina, Colletta, Cosimo, Colombo, Massimo, Colombo, Silvia, Coman, Felicia, Cool, Mike, Coppola, Carmine, Correa, Maria Cassia, Costa, Chiara, Craxi, Antonio, Curescu, Manuela, D'Amico, Emilio, D'Angelo, Salvatore, Daryani, Nasser Ebrahimi, De Galocsy, Chantal, Debzi, Nabil, Decaestecker, Jochen, Delic, Dragan, Delwaide, Jean, Demelia, Luigi, Derbala, Moutaz, Deron, Zbigniew, Di Giacomo, Antonio, Di Perri, Giovanni, Dimitroulopoulos, Dimitrios, Dohaibi, Ahmad, Drakoulis, Christos, Drenaggi, Davide, Elefsiniotis, Ioannis, Enyedi, Judit, Erne, Elke, Esmat, Gamal, Evgenidis, Nikolaos, Fabri, Milotka, Faria, Telo, Ferenci, Peter, Fernandes, Julio Cesar, Ferrari, Carlo, Ferraz, Maria Lucia, Fierbinteanu Braticevici, Carmen, Flisiak, Robert, Foster, Graham R., Foti, Giuseppe, Francisci, Daniela, Fried, Katalin, Gabr, Mamdouh, Ganga, Roberto, George, Christophe, Gervain, Judit, Gheorghe, Liana, Giannoulis, Grigoris, Gietka, Andrzej, Giguere, Alain, Gomide, Geisa, Guerreiro, Hor\ue1cio, Guessab, Nawal, Halota, Waldemar, Han, Sang Young, Hanno, Abdelfatah, Harxhi, Arjan, Hashmi, Zahid, Hassanein, Tarek, Hausinger, P\ue9ter, Henrion, Jean, Holoman, Jozef, Horsmans, Yves, Hoste, Paul, Houmani, Zaher, Hunyady, Bela, Ibrahimpasic, Nevzeta, Ionita Radu, Florentina, Ivanovski, Ljubomir, Jablkowski, Maciej, Jankovic, Goran, Janssens, Filip, Jarcuska, Peter, Jesic, Rada, Joksimovic, Nenad, Junior, Elson Martins, Juriens, Ir\ue8ne, Kanatakis, Stilianos, Karagiannis, Ioannis, Karatapanis, Stilianos, Ketikoglou, Ioannis, Kim, Yoonjun, Konstantinovic, Ljiljana, Krkoska, Dusan, Kupcova, Viera, Lakner, Lilla, Langlet, Philippe, Lasser, Luc, Laukens, Pierre, Lawate, Parimal, Lee, Yun Nah, Lefebvre, Veronique, Lencu, Monica, Lengyel, Gabriella, Lesch, Miklos, Lipczynski, Artur, Livia, Hara, Luaia, Rosang, Lyra, Andre, Macedo, Guilherme, Mahindad, Nadir, Mahiou, Hassene, Makkai, Erzs\ue9bet, Malhado, Jos\ue9, Manesis, Emmanuel, Mangia, Alessandra, Manolakopoulos, Spilios, Mansinho, Kamal, Martinet, Jean Paul, Masood, Siddiq, Matarazzo, Filippo, Mazur, Wlodzimierz, Mazzella, Giuseppe, Mazzeo, Maurizio, Megna, Angelo Salomone, Mela, Maria, Mello, Carlos Eduardo, Memoli, Massimo, Memon, Sadik, Mendes, Claudio, Merat, Shahin, Mesihovic, Rusmir, Michielsen, Peter, Miftode, Egidia, Mimidis, Konstantinos, Mohsin, Aftab, Montalbano, Marzia, Montalto, Giuseppe, Monteverde, Carlos, Motoc, Adriana, Mousoulis, Georgios, Mulkay, Jean Pierre, Musat, Marioara, Musialik, Joanna, Nagorni, Aleksandar, Nagral, Aabha, Nagy, Istvan, Nassiri Toosi, Mohsen, Nemes\ue1nszky, Elem\ue9r, Nevens, Frederik, Nikolopoulou, Vassiliki, Nozic, Darko, Olszok, Iwona, Olteanu, Dan, Oltman, Marian, Omar, Ashraf, Orfanou, Eleni, Orlandini, Alessandra, Orszulak, Grazyna, Ozsv\ue1r, Zs\uf3fia, Paik, Seung Woon, Parikh, Samir, Pascu, Oliviu, Passariello, Nicola, Patai, \uc1rp\ue1d, Peixe, Paula, Pelemis, Mijomir, Pereira, Patricia, Philip, Mathew, Picciotto, Antonio, Piekarska, Anna, Piekos, Tomasz, Pieri, Alessandro, Pietrangelo, Antonello, Pigozzi, Maria Graziella, Pirisi, Mario, Preotescu, Liliana, Quirino, Tiziana, Racz, Istvan, Radowska, Danuta, Raimondo, Giovanni, Ramos, Jos\ue9 Presa, Rao, Padaki, Rapaccini, Gian Ludovico, Reddy, K. Rajender, Reynaert, Hendrik, Ribiczey, P\ue1l, Rizzardini, Giuliano, Rizzetto, Mario, Robaeys, Geert, Roxo, Fausto, Ruiz, Fernando Jose, Russello, Maurizio, Russo, FRANCESCO PAOLO, Sabusco, Giuseppe, Santantonio, Teresa, Saracco, Giorgio Maria, Sarmento Castro, Rui, Schneider, Ferenc, Schreter, Ivan, Schuller, J\ue1nos, Serejo, F\ue1tima, Servais, Benoit, Shabanaj, Gentian, Sharara, Ala, Shiffman, Mitchell L., Sieklucki, Jerzy, Silaghi, Rodica, Silva, Giovanni, Silva, Mariliza Henrique, Simon, Krzysztof, Skladany, Lubomir, Soardo, Giorgio, Somani, Sanjay, Sood, Ajit, Spinzi, Giancarlo, Sporea, Ioan, Sprengers, Dirk, Stan, Marioara, Stanciu, Carol, Streinu Cercel, Adrian, Svorcan, Petar, Szalay, Ferenc, Szantova, Maria, Szentgy\uf6rgyi, L\ue1szl\uf3, Szlauer, Bronislawa, Tallarico, Ludovico, Teixeira, Rosangela, Todorovic, Zoran, Tolvaj, Gyula, Tornai, Istvan, Trifan, Anca, Tsianos, Epameinondas, Tundo, Paolo, Tusnadi, Anna, V\ue1czi, Zsuzsanna, Vafiadi Zoubouli, Irini, Valente, Cristina, Van Der Meersch, Filip, Van Vlierberghe, Hans, Varga, Marta, Varghese, Rosh, Varkonyi, Istvan, Velez, Jorge, Verhaz, Antonija, Verucchi, Gabriella, Vinci, Maria, Vincze, Aron, Vinelli, Francesco, Warakomska, Iwona, Warzee, Philippe, Yaghi, Cesar, Yang, Jinmo, Yousry, Ayman, Zaarour, Fouad, Zali, Mohammad Reza, Zignego, Anna Linda, Zuin, Massimo   +303 more
core   +1 more source

Evaluation of Ribavirin–Poloxamer Microparticles for Improved Intranasal Absorption

Pharmaceutics, 2021
Ribavirin is a water-soluble antiviral compound which, owing to its inability to cross the blood–brain barrier, has limited effectiveness in treating viruses affecting the central nervous system.
Dipy M. Vasa, Zainab Bakri, Maureen D. Donovan, Lauren A. O’Donnell, Peter L. D. Wildfong   +4 more
doaj   +1 more source

Lethal Mutagenesis of Picornaviruses with N-6-Modified Purine Nucleoside Analogues [PDF]

, 2008
RNA viruses exhibit extraordinarily high mutation rates during genome replication. Nonnatural ribonucleosides that can increase the mutation rate of RNA viruses by acting as ambiguous substrates during replication have been explored as antiviral agents ...
Barr, Eric W., Bollinger, J. Martin, Jr., Brown, Daniel M., Cameron, Craig E., Edathil, Jocelyn P., Galarraga, Jessica E., Graci, Jason D., Harki, Daniel A., Loakes, David, Peterson, Blake R., Smidansky, Eric D., Too, Kathleen   +11 more
core   +4 more sources

Sofosbuvir and Ribavirin Therapy for Children Aged 3 to <12 Years With Hepatitis C Virus Genotype 2 or 3 Infection. [PDF]

, 2020
Currently, the only approved hepatitis C virus (HCV) treatment for children aged <12 years is pegylated interferon plus ribavirin. In an open-label study, we evaluated the safety and efficacy of sofosbuvir plus ribavirin for 12 weeks in children aged ...
Balistreri, William F, Bansal, Sanjay, Brainard, Diana M, Davison, Suzanne, Feiterna-Sperling, Cornelia, Gillis, Lynette A, Gonzalez-Peralta, Regino P, Hsueh, Chia-Hsiang, Indolfi, Giuseppe, Jonas, Maureen M, Kelly, Deidre A, Lin, Chuan-Hao, Massetto, Benedetta, Murray, Karen F, Nightingale, Scott, Parhy, Bandita, Rosenthal, Philip, Schwarz, Kathleen B, Shao, Jiang, Sokal, Etienne M, Wirth, Stefan   +20 more
core  

Treating HCV with ribavirin analogues and ribavirin-like molecules [PDF]

Journal of Antimicrobial Chemotherapy, 2005
Nucleos(t)ide analogues have proven useful in the treatment of viral infections. Ribavirin is a nucleoside, guanosine analogue, whose mechanisms of action include inhibition of inosine monophosphate dehydrogenase (IMPDH), which is the key step in de novo guanine synthesis, a requirement for viral replication.
openaire   +3 more sources

Enhancement of Crystallization Process of the Organic Pharmaceutical Molecules through High Pressure

Crystals, 2022
The enhancement of the crystallization process through high pressures was studied by using ribavirin (RVB) as a model compound. The effects of high pressure on crystallization thermodynamics, nucleation kinetics, and process yield were evaluated and ...
Yaoguang Feng, Hongxun Hao, Yiqing Chen, Na Wang, Ting Wang, Xin Huang   +5 more
doaj   +1 more source

Adverse Skin Reactions due to Ribavirin in Hepatitis C Combination Therapy with Pegylated Interferon-α2a

Case Reports in Dermatology, 2013
The introduction of ribavirin to hepatitis C combination therapy with pegylated interferon (PEG-IFN)-α2a has improved sustained responses, but it has been accompanied by an increased incidence of cutaneous side effects. Most cases of drug eruption caused
Masahisa Shindo, Isamu Terai
doaj   +1 more source

Drug Repurposing For SARS-COV-2 Using Molecular Docking [PDF]

arXiv, 2022
Drug repurposing is an unconventional approach that is used to investigate new therapeutic aids of existing and shelved drugs. Recent advancement in technologies and the availability of the data of genomics, proteomics, transcriptomics, etc., and with the accessibility of large and reliable database resources, there are abundantly of opportunities to ...
arxiv