Results 21 to 30 of about 76,496 (274)

Inhibition of tick-borne encephalitis virus in cell cultures by ribavirin

open access: yesFrontiers in Microbiology, 2023
Tick-borne encephalitis virus (TBEV) belonging to arboviruses is a major member of zoonotic pathogens. TBEV infection causes severe human encephalitis without specific antiviral drugs.
Wan-Da Tang   +5 more
doaj   +1 more source

Acute Hepatic Failure in Crimean‐Congo Hemorrhagic Fever: A Case Report [PDF]

open access: yesClin Case Rep
ABSTRACT Acute hepatic failure is a rare but critical complication of Crimean‐Congo hemorrhagic fever (CCHF). This case presents acute hepatic failure with liver enzyme elevation and thrombocytopenia. The patient responded well to treatment that included ribavirin, lactulose, rifaximin, and supportive therapies.
Shahatta A   +8 more
europepmc   +2 more sources

Effect of Ribavirin Alone or Combined with Silymarin on Carbon Tetrachloride Induced Hepatic Damage in Rats

open access: yesDrug Target Insights, 2007
The effect of the antiviral agent ribavirin given alone or in combination with Silymarin on the development of liver injury induced in rats with carbon tetrachloride (CCl 4 ; 2.8 ml/kg followed by 1.4 ml/kg after one week) was studied. Ribavirin at three
Omar M.E. Abdel Salam M.D., Ph.D.   +3 more
doaj   +2 more sources

Time to reconsider the role of ribavirin in Lassa fever.

open access: yesPLoS Neglected Tropical Diseases, 2021
Ribavirin is the only available Lassa fever treatment. The rationale for using ribavirin is based on one clinical study conducted in the early 1980s. However, reanalysis of previous unpublished data reveals that ribavirin may actually be harmful in some ...
Alex Paddy Salam   +5 more
doaj   +1 more source

Rituximab-Containing Treatment Regimens May Imply a Long-Term Risk for Difficult-To-Treat Chronic Hepatitis E [PDF]

open access: yes, 2020
Hepatitis E virus (HEV) infection is an emerging disease in industrialized countries which is usually characterized by a self-limited course. However, there is an increased risk of HEV persistence in immunocompromised risk populations, comprising ...
Biedermann, Paula   +7 more
core   +1 more source

Psychomotor activity and body weight gain after exposure to low ribavirin doses in rats: role of treatment duration [PDF]

open access: yesArchives of Biological Sciences, 2019
Clinically-related basic studies on the behavioral effects of ribavirin treatment are still lacking despite its wide use as an antiviral medication. This paper considers the effects of low ribavirin doses (10, 20 and 30 mg/kg/day) on psychomotor activity
Petković Branka   +6 more
doaj   +1 more source

Selection of hepatitis C virus resistant to ribavirin

open access: yesVirology Journal, 2011
Background Given the side effects associated with intravenous injections of interferon, an interferon-free regimen for the treatment of HCV infections is highly desirable.
Feinstone Stephen M   +2 more
doaj   +1 more source

Impact of safety-related dose reductions or discontinuations on sustained virologic response in HCV-infected patients: Results from the GUARD-C Cohort [PDF]

open access: yes, 2016
BACKGROUND: Despite the introduction of direct-acting antiviral agents for chronic hepatitis C virus (HCV) infection, peginterferon alfa/ribavirin remains relevant in many resource-constrained settings.
Abbas, Zaigham   +303 more
core   +1 more source

Combined therapy with danazol, pegilated interferon, and ribavirin improves thrombocytopenia and liver injury in rats with fibrosis

open access: yesAnnals of Hepatology, 2007
The aim of this study was to investigate the effects of combinations of pegilated–interferon (PEG–IFN), ribavirin, and danazol on thrombocytopenia and liver injury in rats with fibrosis.
Guillermo Cabrera Álvarez   +7 more
doaj   +1 more source

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