Results 81 to 90 of about 76,496 (274)

Ribavirin for Crimean-Congo hemorrhagic fever: systematic review and meta-analysis

BMC Infectious Diseases, 2010
Background Crimean-Congo hemorrhagic fever epidemics often occur in areas where health services are limited, and result in high case fatality rates. Besides intensive care, ribavirin is often recommended.
G Gail, Thomas Sherine, Soares-Weiser Karla, Garner Paul   +3 more
doaj   +1 more source

Prospective observational study on the pharmacokinetic properties of the Irrua ribavirin regimen used in routine clinical practice in patients with Lassa fever in Nigeria

BMJ Open, 2020
Introduction Lassa fever (LF) is a severe and often fatal systemic disease in humans and affects a large number of countries in West Africa. Treatment options are limited to supportive care and the broad-spectrum antiviral agent ribavirin.
Michael Ramharter, Osahogie Edeawe, Peter Akhideno, Gloria Eifediyi, Till F Omansen, Christine Wagner, Francisca Sarpong, Till Koch, Sebastian Wicha, Florian Kurth, Sophie Duraffour, Lisa Oestereich, Meike Pahlmann, Sylvanus Okogbenin, Ephraim Ogbaini-Emovon, Stephan Günther, Mirjam Groger   +16 more
doaj   +1 more source

ITPA Genotypes Predict Anemia but Do Not Affect Virological Response with Interferon-Free Faldaprevir, Deleobuvir, and Ribavirin for HCV Infection. [PDF]

PLoS ONE, 2015
BACKGROUND & AIM:Whether inosine triphosphatase (ITPA) gene polymorphisms predict anemia during interferon-free therapy in chronic hepatitis C virus (HCV)-infected patients is unknown.
Tarik Asselah, Stefan Zeuzem, Vicente Soriano, Jean-Pierre Bronowicki, Ansgar W Lohse, Beat Müllhaupt, Marcus Schuchmann, Marc Bourlière, Maria Buti, Stuart K Roberts, Edward J Gane, Jerry O Stern, Florian Voss, Patrick Baum, John-Paul Gallivan, Wulf O Böcher, Federico J Mensa   +16 more
doaj   +1 more source

Role of therapeutic drug monitoring in pulmonary infections : use and potential for expanded use of dried blood spot samples [PDF]

, 2015
Respiratory tract infections are among the most common infections in men. We reviewed literature to document their pharmacological treatments, and the extent to which therapeutic drug monitoring (TDM) is needed during treatment.
Akkerman, Onno W, Alffenaar, Jan-Willem C, Bolhuis, Mathieu S, Hofman, Susan, Koster, Remco A, Stove, Christophe, van Assen, Sander   +6 more
core   +2 more sources

Harnessing Camalexin as a Sustainable and Ecofriendly Strategy to Control Harmful Phytopathogens

Plant Pathology, EarlyView.
We review camalexin, a natural antimicrobial from Brassicaceae plants, which shows broad‐spectrum pathogen control and potential as an ecofriendly crop protection agent, with challenges and future directions. ABSTRACT Camalexin is a natural phytoalexin found in the Brassicaceae family, which has shown antimicrobial activity against diverse microbial ...
Farjana Rahman Lopa, Farzana Nazneen Snigdha, Rhea Amor Lumactud, Md Maniruzzaman Sikder   +3 more
wiley   +1 more source

The Neurological Effects of Ribavirin in Crimean-congo Hemorrhagic Fever Symptoms: A Systematic Review [PDF]

Caspian Journal of Neurological Sciences
Background: Ribavirin is widely used in treating viral infections like Crimean-Congo hemorrhagic fever (CCHF), which is a severe disease with high morbidity and mortality.
Hossein Hatami, Mohammad Javad Nasiri, Kimia Eyvani, Mobina Fatthy   +3 more
doaj  

Desirable Characteristics of Hepatitis C Treatment Regimens: A Review of What We Have and What We Need. [PDF]

, 2016
There have been dramatic advancements in the treatment of chronic hepatitis C (HCV) infection. This is largely due to the approval of several direct-acting antiviral agents (DAAs) from a variety of medication classes with novel mechanisms of action ...
Bidell, Monique R, Faragon, John, McLaughlin, Milena, Morse, Caroline, Patel, Nimish   +4 more
core   +2 more sources

How Will AI Shape the Future of Pandemic Response? Early Clues From Data Analytics

Risk Analysis, EarlyView.
ABSTRACT The COVID‐19 pandemic has exposed critical gaps in our management of systemic risks within complex, interconnected systems. This review examines 10 key areas where artificial intelligence (AI) and data analytics can significantly enhance pandemic preparedness, response, and recovery.
Benjamin D. Trump, Stephanie Galaitsi, Jeff Cegan, Igor Linkov   +3 more
wiley   +1 more source

Ribavirin exerts differential effects on functions of Cd4+ Th1, Th2, and regulatory T cell clones in hepatitis C. [PDF]

PLoS ONE, 2012
Ribavirin improves outcomes of therapy in chronic hepatitis C but its mode of action has still remained unclear. Since ribavirin has been proposed to modulate the host's T cell responses, we studied its direct effects on CD4(+) T cell clones with diverse
Bettina Langhans, Hans Dieter Nischalke, Simone Arndt, Ingrid Braunschweiger, Jacob Nattermann, Tilman Sauerbruch, Ulrich Spengler   +6 more
doaj   +1 more source

Drop-out rate from the liver transplant waiting list due to HCC progression in HCV-infected patients treated with direct acting antivirals. [PDF]

, 2017
BACKGROUND & AIM: concerns about an increased hepatocellular carcinoma (HCC) recurrence rate following directly acting antiviral (DAA) therapy in cirrhotic patients with a prior complete oncological response have been raised. Data regarding the impact of
Angeli, Paolo, Burra, Patrizia, Cillo, Umberto, Farinati, Fabio, Ferrarese, Alberto, Forton, Dm, Franceschet, E, Gambato, M, Germani, Giacomo, Mescoli, Claudia, Romano, Antonietta, Rugge, Massimo, Russo, FRANCESCO PAOLO, Senzolo, Marco, Shalaby, S, Vitale, A, Zanetto, Alberto   +16 more
core   +1 more source