Results 81 to 90 of about 74,231 (262)
SYNERGY IN MIXED RIBAVERIN-INTERFERON AQUEOS SOLUTIONS
Сеченовский вестник, 2017 Spectrophotometric method of ribavirin determination in aqueous solutions was improved. Feasibility of ribavirin determination in the presence of protein was confirmed.
K. Kienskaya +8 more
doaj
Race affects SVR12 in a large and ethnically diverse hepatitis C-infected patient population following treatment with direct-acting antivirals: Analysis of a single-center Department of Veterans Affairs cohort. [PDF]
, 2018 Hepatitis C virus (HCV) infection is a major cause of chronic liver disease. HCV cure has been linked to improved patient outcomes. In the era of direct-acting antivirals (DAAs), HCV cure has become the goal, as defined by sustained virological response ...
Benhammou, Jihane N +9 more
core +1 more source
IDCases, 2023 Persistent Hepatitis E Virus infection (HEV) is a rare but increasingly recognised condition in immunocompromised individuals. Untreated, this infection can rapidly progress to cirrhosis.
Jennifer Gallacher +4 more
doaj
Mathematical Modelling and Analysis of Transmission Dynamics of Lassa fever [PDF]
arXiv, 2019 In this work, a periodically-forced seasonal non-autonomous system of a non-linear ordinary differential equation is developed that captures the dynamics of Lassa fever transmission and seasonal variation in the birth of mastomys rodents where time was measured in days to capture seasonality.
arxiv
The Nasal–Brain Drug Delivery Route: Mechanisms and Applications to Central Nervous System Diseases
MedComm, Volume 6, Issue 6, June 2025.Τhe BBB restricts CNS drug delivery. NBDD bypasses the BBB via olfactory/trigeminal routes, enabling CNS delivery of therapeutic (small molecules, biologics, nucleic acids) for neurodegenerative/psychiatric disorders and brain tumors using advanced NBDD delivery systems (e.g nanocarriers) to enhance targeting and bioavailability.
Yi Qiu +7 more
wiley +1 more source
Tracking TCRß sequence clonotype expansions during antiviral therapy using high-throughput sequencing of the hypervariable region [PDF]
, 2016 To maintain a persistent infection viruses such as hepatitis C virus (HCV) employ a range of mechanisms that subvert protective T cell responses. The suppression of antigen-specific T cell responses by HCV hinders efforts to profile T cell responses ...
Arvind H Patel +10 more
core +3 more sources
Ribavirin Contributes to Hepatitis C Virus Suppression by Augmenting pDC Activation and Type 1 IFN Production. [PDF]
PLoS ONE, 2015 Ribavirin is used as a component of combination therapies for the treatment of chronic hepatitis C virus (HCV) infection together with pegylated interferon and/or direct-acting antiviral drugs. Its mechanism of action, however, is not clear.
Yang Wang +7 more
doaj +1 more source
VIEW, Volume 6, Issue 3, June 2025.A retrospective, multicenter cohort study was conducted across nine hospitals in Henan Province, aiming to evaluate the efficacy and safety of azvudine in hospitalized COVID‐19 patients with kidney disease. Through the application of Kaplan‒Meier and multivariate Cox regression analyses, it was found that azvudine may have potential effects in reducing
Bo Yu +13 more
wiley +1 more source
A practical approach to managing patients with HCV infection. [PDF]
, 2006 Hepatitis C virus (HCV) infection is a major worldwide public health concern. It is a common cause of chronic liver disease and hepatocellular carcinoma. HCV antibody and HCV RNA testing are available diagnostic studies that offer high degree of accuracy.
Hu, Ke-Qin, Huang, Richard H
core +3 more sources
PLoS ONE, 2019 Epithelial ovarian cancers are insidious pathologies that give a poor prognosis due to their late discovery and the increasing emergence of chemoresistance. Development of small pharmacological anticancer molecules remains a major challenge.
Anaïs Wambecke +8 more
doaj +1 more source