Results 71 to 80 of about 67,958 (288)

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

Advanced Science, EarlyView.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun, Teng Ma, Hao Jin, Zelong Li, Yi Cheng, Jingjin Li, Lai‐Yu Kwok, Zhihong Sun   +7 more
wiley   +1 more source

Riboflavin Production by Steady-State Continuous Cultures of Hyphopichia wangnamkhiaoensis in a Bubble Column Bioreactor

Microorganisms
Riboflavin is biosynthesized and excreted extracellularly by the novel yeast Hyphopichia wangnamkhiaoensis. The steady-state kinetics of cell growth, substrate consumption, and riboflavin production by H.
Raziel Arturo Jiménez-Nava, Griselda Ma. Chávez-Camarillo, Eliseo Cristiani-Urbina   +2 more
doaj   +1 more source

Riboflavin Biosynthesis and Overproduction by a Derivative of the Human Gut Commensal Bifidobacterium longum subsp. infantis ATCC 15697

Frontiers in Microbiology, 2020
Riboflavin or vitamin B2 is the precursor of the essential coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). Despite increased interest in microbial synthesis of this water-soluble vitamin, the metabolic pathway for riboflavin ...
Ana Solopova, Francesca Bottacini, Elena Venturi degli Esposti, Alberto Amaretti, Alberto Amaretti, Stefano Raimondi, Maddalena Rossi, Maddalena Rossi, Douwe van Sinderen, Douwe van Sinderen   +9 more
doaj   +1 more source

Riboflavin Inhibits Histamine-Dependent Itch by Modulating Transient Receptor Potential Vanilloid 1 (TRPV1)

Frontiers in Molecular Neuroscience, 2021
Riboflavin, also known as vitamin B2, isfound in foods and is used as a dietary supplement. Its deficiency (also called ariboflavinosis) results in some skin lesions and inflammations, such as stomatitis, cheilosis, oily scaly skin rashes, and itchy ...
Kihwan Lee, Young In Choi, Sang-Taek Im, Sung-Min Hwang, Han-Kyu Lee, Jay-Zoon Im, Yong Ho Kim, Sung Jun Jung, Chul-Kyu Park   +8 more
doaj   +1 more source

Selective tumor cell death induced by irradiated riboflavin through recognizing DNA G-T mismatch

, 2017
Riboflavin (vitamin B2) has been thought to be a promising antitumoral agent in photodynamic therapy, though the further application of the method was limited by the unclear molecular mechanism.
Wu, JS, Zou, JW, Chen, GY, Yuan, Y, Chen, R, Jiang, F (reprint author), Peking Univ, Lab Computat Chem & Drug Design, Lab Chem Genom, Shenzhen Grad Sch, Shenzhen 518055, Peoples R China., Tang, Z, Tang, Z (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Sichuan, Peoples R China., Wang, J, Chen, LQ, Zhao, YY, Wang, J (reprint author), Chengdu Univ Tradit Chinese Med, Coll Pharm, Chengdu 611137, Sichuan, Peoples R China., Li, S, Jiang, F   +13 more
core   +1 more source

CAR‐Engineered Cell Therapies Beyond Cancer: Reprogramming Fibrosis and Immune‐Mediated Inflammation

Advanced Science, EarlyView.
CAR‐engineered cell therapies are expanding beyond cancer toward immune resetting, pathological‐cell clearance, matrix remodeling, and microenvironmental reprogramming in autoimmune, inflammatory, and fibrotic diseases. This Review compares CAR‐T, CAR‐macrophage, and CAR‐NK platforms and proposes controllable spatiotemporal reprogramming to align ...
Peng Jun Xu, Zhou Jing Zhang, Jing Jin, Hai Yuan Xu, Ya Xin Gu, Qian Qian Yang, You Lang Zhou   +6 more
wiley   +1 more source

Statistical optimization and random mutagenesis for improved riboflavin production from Lactiplantibacillus pentosus SV13 isolated from dosa batter

Discover Applied Sciences
Aim The study aims to identify and develop an efficient bacterial strain for the production of riboflavin. The developed strain could be a starter culture in the food and pharmaceutical industries.
R. Srivatsan, M. Hemalatha, Sanjeev K. Ganesh, V. Mohanasrinivasan, C. Subathra Devi   +4 more
doaj   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

Advanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng, Jiateng Zhou, Xiaoyu Guo, Ting Hong, Xuelian Li, Xingyu Wei, Chanhua Zhang, Xixue Zhang, Songbin Liu, Yulin Zhang, Liangfang Yao, Lina Huang, Weidong Gu   +12 more
wiley   +1 more source

Comparison of Corneal Riboflavin Gradients Using Dextran and HPMC Solutions.

, 2016
PURPOSE To determine the riboflavin concentration gradient in the anterior corneal stroma when using hydroxypropyl methylcellulose (HPMC) or dextran as the carrier agent.
Fischinger, Isaak, Ripken, Tammo, Seiler, Günter Theodor Michael, Früh Epstein, Beatrice, Ehmke, Tobias, Heisterkamp, Alexander   +5 more
core   +1 more source

Synthetic Shewanella‐Bacillus Microbial Consortia for Enhanced Metal Oxide Leaching From Spent Lithium‐Ion Batteries Using Brewing Wastewater as Leaching Agent

Advanced Science, EarlyView.
A recycling approach of spent lithium‐ion batteries is developed using brewing wastewater as the leaching agent and an engineering microbial consortium as the biocatalyst. Shewanella oneidensis reduces spent LiNixCoyMn1‐x‐yO2 cathodes via extracellular electron transfer, while Bacillus subtilis removes residual ethanol to eliminate inhibition.
Baocai Zhang, Chunxiao Qiao, Huichun Liu, Yiyun Wang, Yan Liu, Huan Yu, Junqi Zhang, Chao Li, Deguang Wu, Qulai Tang, Zhiwen Wang, Danni Zhang, Dake Xu, Feng Li, Hao Song   +14 more
wiley   +1 more source