Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis [PDF]
Redox Biology, 2022 Ariboflavinosis is a pathological condition occurring as a result of riboflavin deficiency. This condition is treatable if detected early enough, but it lacks timely diagnosis.
Tirthankar Sinha +7 more
doaj +2 more sources
Premature farrowing and stillbirths in two organic sow farms due to riboflavin deficiency [PDF]
Porcine Health Management, 2023 Background Riboflavin deficiency can lead to premature farrowing, stillborn piglets, weak-born piglets and neonatal death. Riboflavin (vitamin B2) is considered essential for reproductive function. The longer the period on riboflavin-deficient diets, the
Camilla Torreggiani +7 more
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Effects of riboflavin deficiency and high dietary fat on hepatic lipid accumulation: a synergetic action in the development of non-alcoholic fatty liver disease [PDF]
Nutrition & MetabolismBackground Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation in the liver. Riboflavin, one of water soluble vitamins, plays a role in lipid metabolism and antioxidant function.
Yanxian Wang +6 more
doaj +2 more sources
Role of riboflavin deficiency in malaria pathophysiology. [PDF]
PLoS PathogensThe emergence of resistance against antimalarials and insecticides poses a significant threat to malaria elimination strategies. It is crucial to explore potential risk factors for malaria to identify new targets and alternative therapies.
Shweta Sharma +2 more
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Developmental riboflavin deficiency results in structural and functional changes in the neural retina and RPE [PDF]
Redox BiologyThe retina, a metabolically active tissue, relies on adequate flavin levels for optimal function. Our previous research demonstrated that ablation of RTBDN, a retina-specific riboflavin binding protein, plays a pivotal role in maintaining flavin levels ...
Xue Zhao +3 more
doaj +2 more sources
The Anemia of Human Riboflavin Deficiency [PDF]
Blood, 1965 Abstract 1. Riboflavin deficiency was induced in 8 adult males with a riboflavin deficient diet and a riboflavin antagonist, galactoflavin. 2. Each patient developed a normochromic normocytic anemia and reticulocytopenia. 3. The leukocyte counts and platelet counts remained within the normal range throughout
M, LANE, C P, ALFREY
exaly +3 more sources
Brain Sciences, 2022 (1) Background: Riboflavin transporter deficiency (RTD), formerly known as Brown–Vialetto–Van Laere syndrome, is a rare condition that causes a progressive neurological syndrome in early life with features of auditory and optic neuropathy, weakness of ...
Dominic Thyagarajan, Lin Zhang
exaly +3 more sources
The role of riboflavin refeeding in reversing deficiency effects on duck reproductive performance and embryonic development [PDF]
Animal NutritionRiboflavin (vitamin B2) is essential for poultry reproduction and embryonic development. Riboflavin deficiency adversely affects egg hatchability and embryonic survival, but whether these effects are reversible remains unclear. This study aimed to assess
Bo Zhang +9 more
doaj +2 more sources
Riboflavin in neurological diseases: therapeutic advances, metabolic insights, and emerging genetic strategies [PDF]
Frontiers in NeurologyBackgroundRiboflavin (vitamin B2), a precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), is essential for mitochondrial function, redox balance, and neuronal viability.
Zhiming Tao +11 more
doaj +2 more sources
Riboflavin Deficiency—Implications for General Human Health and Inborn Errors of Metabolism [PDF]
International Journal of Molecular Sciences, 2020 Peter Bross +2 more
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