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Premature farrowing and stillbirths in two organic sow farms due to riboflavin deficiency [PDF]

Porcine Health Management, 2023
Background Riboflavin deficiency can lead to premature farrowing, stillborn piglets, weak-born piglets and neonatal death. Riboflavin (vitamin B2) is considered essential for reproductive function. The longer the period on riboflavin-deficient diets, the
Camilla Torreggiani, Dominiek Maes, Luigi Franchi, Valeria Raffi, Elena Borri, Alice Prosperi, Chiara Chiapponi, Andrea Luppi   +7 more
doaj   +3 more sources

Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis [PDF]

Redox Biology, 2022
Ariboflavinosis is a pathological condition occurring as a result of riboflavin deficiency. This condition is treatable if detected early enough, but it lacks timely diagnosis.
Tirthankar Sinha, Larissa Ikelle, Mustafa S. Makia, Ryan Crane, Xue Zhao, Mashal Kakakhel, Muayyad R. Al-Ubaidi, Muna I. Naash   +7 more
doaj   +2 more sources

Riboflavin Deficiency—Implications for General Human Health and Inborn Errors of Metabolism [PDF]

International Journal of Molecular Sciences, 2020
As an essential vitamin, the role of riboflavin in human diet and health is increasingly being highlighted. Insufficient dietary intake of riboflavin is often reported in nutritional surveys and population studies, even in non-developing countries with ...
Peter Bross, Signe Mosegaard, Graziana Dipace   +2 more
exaly   +3 more sources

B2 or Not B2: A Systematic Literature Review on Migraine Headaches and Riboflavin Deficiency [PDF]

Headache Medicine, 2023
Objective To assess the prevalence of riboflavin deficiency in patients with migraines or headaches. Methods Systematic review of the literature following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
Thomas Varkey, Jordan Farhat, Joshua Tobin   +2 more
doaj   +2 more sources

Effects of riboflavin deficiency and high dietary fat on hepatic lipid accumulation: a synergetic action in the development of non-alcoholic fatty liver disease [PDF]

Nutrition & Metabolism
Background Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation in the liver. Riboflavin, one of water soluble vitamins, plays a role in lipid metabolism and antioxidant function.
Yanxian Wang, Xiangyu Bian, Min Wan, Weiyun Dong, Weina Gao, Zhanxin Yao, Changjiang Guo   +6 more
doaj   +2 more sources

Role of riboflavin deficiency in malaria pathophysiology. [PDF]

PLoS Pathogens
The emergence of resistance against antimalarials and insecticides poses a significant threat to malaria elimination strategies. It is crucial to explore potential risk factors for malaria to identify new targets and alternative therapies.
Shweta Sharma, Arathy Ramachandran, Amit Sharma   +2 more
doaj   +2 more sources

Developmental riboflavin deficiency results in structural and functional changes in the neural retina and RPE [PDF]

Redox Biology
The retina, a metabolically active tissue, relies on adequate flavin levels for optimal function. Our previous research demonstrated that ablation of RTBDN, a retina-specific riboflavin binding protein, plays a pivotal role in maintaining flavin levels ...
Xue Zhao, Mustafa S. Makia, Muna I. Naash, Muayyad R. Al-Ubaidi   +3 more
doaj   +2 more sources

Gut microbiota-derived riboflavin mediates protective effects of MUC2 in acute pancreatitis via CD40-macrophage pathway [PDF]

Microbiome
Background Gut barrier dysfunction is critical in the pathogenesis of acute pancreatitis (AP), yet the underlying mechanisms remain unclear. Mucin 2 (MUC2), the primary component of the intestinal mucus layer, is essential for gut homeostasis and ...
Yang Fu, Nuoming Yin, Zehua Huang, Wenfei Qin, Binqiang Xu, Huizhen Huang, Jia Hu, Mengyan Cui, Qixiang Mei, Junjie Fan, Yingying Lu, Qiaoli Jiang, Junjie Hu, Chunlan Huang, Yue Zeng   +14 more
doaj   +2 more sources

Genotype-environment interaction drives the onset of riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency in carriers of single heterozygous ETFDH variants [PDF]

Cell Communication and Signaling
Background Riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency (RR-MADD) is an autosomal recessive disorder of fatty acid oxidation predominantly caused by variants in the ETFDH gene.
Jing Ma, Huiqiu Zhang, Jiaqi Jiao, Menghan Su, Junsen Zhao, Dan Liu, Qi Wen, Jianli Wang, Juan Wang, Weisong Duan, Xueli Chang, Junhong Guo, Wei Zhang   +12 more
doaj   +2 more sources

Update on riboflavin and multiple sclerosis: a systematic review [PDF]

Iranian Journal of Basic Medical Sciences, 2017
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Riboflavin plays an important role in myelin formation, and its deficiency is implicated as a risk factor for multiple sclerosis.
Mahshid Naghashpour, Sima Jafarirad, Reza Amani, Alireza Sarkaki, Ahmad Saedisomeolia   +4 more
doaj   +1 more source