Results 1 to 10 of about 33,358 (251)

Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis [PDF]

Redox Biology, 2022
Ariboflavinosis is a pathological condition occurring as a result of riboflavin deficiency. This condition is treatable if detected early enough, but it lacks timely diagnosis.
Tirthankar Sinha, Larissa Ikelle, Mustafa S. Makia, Ryan Crane, Xue Zhao, Mashal Kakakhel, Muayyad R. Al-Ubaidi, Muna I. Naash   +7 more
doaj   +4 more sources

Premature farrowing and stillbirths in two organic sow farms due to riboflavin deficiency [PDF]

Porcine Health Management, 2023
Background Riboflavin deficiency can lead to premature farrowing, stillborn piglets, weak-born piglets and neonatal death. Riboflavin (vitamin B2) is considered essential for reproductive function. The longer the period on riboflavin-deficient diets, the
Camilla Torreggiani, Dominiek Maes, Luigi Franchi, Valeria Raffi, Elena Borri, Alice Prosperi, Chiara Chiapponi, Andrea Luppi   +7 more
doaj   +2 more sources

Effects of riboflavin deficiency and high dietary fat on hepatic lipid accumulation: a synergetic action in the development of non-alcoholic fatty liver disease [PDF]

Nutrition & Metabolism
Background Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation in the liver. Riboflavin, one of water soluble vitamins, plays a role in lipid metabolism and antioxidant function.
Yanxian Wang, Xiangyu Bian, Min Wan, Weiyun Dong, Weina Gao, Zhanxin Yao, Changjiang Guo   +6 more
doaj   +2 more sources

Developmental riboflavin deficiency results in structural and functional changes in the neural retina and RPE [PDF]

Redox Biology
The retina, a metabolically active tissue, relies on adequate flavin levels for optimal function. Our previous research demonstrated that ablation of RTBDN, a retina-specific riboflavin binding protein, plays a pivotal role in maintaining flavin levels ...
Xue Zhao, Mustafa S. Makia, Muna I. Naash, Muayyad R. Al-Ubaidi   +3 more
doaj   +2 more sources

Role of riboflavin deficiency in malaria pathophysiology. [PDF]

PLoS Pathogens
The emergence of resistance against antimalarials and insecticides poses a significant threat to malaria elimination strategies. It is crucial to explore potential risk factors for malaria to identify new targets and alternative therapies.
Shweta Sharma, Arathy Ramachandran, Amit Sharma   +2 more
doaj   +2 more sources

The role of riboflavin refeeding in reversing deficiency effects on duck reproductive performance and embryonic development [PDF]

Animal Nutrition
Riboflavin (vitamin B2) is essential for poultry reproduction and embryonic development. Riboflavin deficiency adversely affects egg hatchability and embryonic survival, but whether these effects are reversible remains unclear. This study aimed to assess
Bo Zhang, Jie Wei, Junting Cao, Dongyan Zhang, Guangnan Xing, Yating Li, Ming Xie, Zhengkui Zhou, Shuisheng Hou, Jing Tang   +9 more
doaj   +2 more sources

Riboflavin in neurological diseases: therapeutic advances, metabolic insights, and emerging genetic strategies [PDF]

Frontiers in Neurology
BackgroundRiboflavin (vitamin B2), a precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), is essential for mitochondrial function, redox balance, and neuronal viability.
Zhiming Tao, Zhiming Tao, Zhiming Tao, Jinglu Huo, Jinglu Huo, Jinglu Huo, Xiaosheng Hao, Xiaosheng Hao, Xiaosheng Hao, Jianmin Liang, Jianmin Liang, Jianmin Liang   +11 more
doaj   +2 more sources

Identification of Riboflavin Metabolism Pathway in HepG2 Cells Expressing Genotype IV Swine Hepatitis E Virus ORF3 Protein [PDF]

Veterinary Sciences
(1) Background: Hepatitis E (HE) is a novel zoonotic disease caused by hepatitis E virus (HEV). In particular, swine hepatitis E virus (SHEV) genotype IV is one of the main genotypes that infect humans.
Jing Tu, Shengping Wu, Lingjie Wang, Chi Meng, Gengxu Zhou, Jianhua Guo, Jixiang Li, Liting Cao, Zhenhui Song, Hanwei Jiao   +9 more
doaj   +2 more sources

Riboflavin Transporter Deficiency Type 2: Expanding the Phenotype of the Lebanese Founder Mutation p.Gly306Arg in the SLC52A2 Gene [PDF]

Metabolites
Background: Riboflavin transporter deficiency type 2 is an ultra-rare, yet treatable, inborn error of metabolism. This autosomal recessive disorder is caused by pathogenic mutations in the SLC52A2 gene leading to progressive ataxia, polyneuropathy, and ...
Jean-Marc T. Jreissati, Leonard Lawandos, Julien T. Jreissati, Pascale E. Karam   +3 more
doaj   +2 more sources

Wolbachia-supplemented B-vitamins are critical for blood digestion in the bed bug Cimex lectularius [PDF]

Scientific Reports
Wolbachia, a bacterial endosymbiont, acts as an obligate nutritional mutualist in the bed bug, Cimex lectularius. Wolbachia in C. lectularius (wCle) supplements B-vitamins, namely riboflavin (B2) and biotin (B7), which are deficient in the bed bug’s diet
Elizabeth L. Wiles, Madhavi L. Kakumanu, Coby Schal   +2 more
doaj   +2 more sources