Results 21 to 30 of about 1,257 (238)

Causes and Clinical Sequelae of Riboflavin Deficiency [PDF]

, 2023
Riboflavin, in its cofactor forms flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), plays fundamental roles in energy metabolism, cellular antioxidant potential, and metabolic interactions with other micronutrients, including iron ...
McNulty, Helene, Pentieva, Kristina, Helene McNulty, Mary Ward, Ward, Mary, Kristina Pentieva   +5 more
core   +1 more source

Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis

Redox Biology, 2022
Ariboflavinosis is a pathological condition occurring as a result of riboflavin deficiency. This condition is treatable if detected early enough, but it lacks timely diagnosis.
Tirthankar Sinha, Larissa Ikelle, Mustafa S. Makia, Ryan Crane, Xue Zhao, Mashal Kakakhel, Muayyad R. Al-Ubaidi, Muna I. Naash   +7 more
doaj   +1 more source

Riboflavin Status in Pregnancy and Its Relationship with Blood Pressure, Heart Rate and Risk of Hypertension: Findings from the OptiPREG Observational Study

Proceedings, 2023
Clinical riboflavin deficiency is common in low- and middle-income countries, whilst sub-optimal riboflavin status may be much more prevalent globally than generally recognized, including in high-income countries.
Bethany Duffy, Helene McNulty, Mary Ward, Elina Psara, Emma O’Sullivan, Geraldine Horigan, Kristina Pentieva   +6 more
doaj   +1 more source

Clinical and molecular investigation of 37 Japanese patients with multiple acyl-CoA dehydrogenase deficiency: p.Y507D in ETFDH, a common Japanese variant, causes a mortal phenotype

Molecular Genetics and Metabolism Reports, 2022
Multiple acyl-CoA dehydrogenase deficiency (MADD) is an inherited metabolic disease caused by a defect in electron transfer flavoprotein alpha (ETFA), ETF beta (ETFB), or ETF dehydrogenase (ETFDH), and riboflavin metabolism disorders have recently been ...
Kenji Yamada, Yoshimitsu Osawa, Hironori Kobayashi, Ryosuke Bo, Yuichi Mushimoto, Yuki Hasegawa, Seiji Yamaguchi, Takeshi Taketani   +7 more
doaj   +1 more source

Probiotic Potential of a Novel Vitamin B2-Overproducing Lactobacillus plantarum Strain, HY7715, Isolated from Kimchi

Applied Sciences, 2021
Vitamin B2, also known as riboflavin, is essential for maintaining human health. The purpose of this study was to isolate novel lactic acid bacteria that overproduce vitamin B2 and to validate their potential as probiotics.
Joo-Yun Kim, Eun-Jung Choi, Jae-Ho Lee, Myeong-Seok Yoo, Keon Heo, Jae-Jung Shim, Jung-Lyoul Lee   +6 more
doaj   +1 more source

Abnormal VLCADD newborn screening resembling MADD in four neonates with decreased riboflavin levels and VLCAD activity

JIMD Reports, 2021
Early detection of congenital disorders by newborn screening (NBS) programs is essential to prevent or limit disease manifestation in affected neonates.
Marne C. Hagemeijer, Esmee Oussoren, George J. G. Ruijter, Willem Onkenhout, Hidde H. Huidekoper, Merel S. Ebberink, Hans R. Waterham, Sacha Ferdinandusse, Maaike C. deVries, Marleen C. D. G. Huigen, Leo A. J. Kluijtmans, Karlien L. M. Coene, Henk J Blom   +12 more
doaj   +1 more source

Demand-oriented riboflavin supply of organic broiler using a feed material from fermentation of Ashbya gossypii

Animal, 2021
Alternatives to riboflavin (vitamin B2) production by recombinant microorganisms are needed in organic poultry production, but are cost-intensive, so that a demand-oriented riboflavin supply is necessary. Details on the riboflavin requirements of organic
C. Lambertz, J. Leopold, S. Ammer, F. Leiber, B. Thesing, C. Wild, K. Damme   +6 more
doaj   +1 more source

Supplementation of iron alone and combined with vitamins improves haematological status, erythrocyte membrane fluidity and oxidative stress in anaemic pregnant women [PDF]

, 2010
Pregnancy is a condition exhibiting increased susceptibility to oxidative stress, and Fe plays a central role in generating harmful oxygen species. The objective of the present study is to investigate the changes in haematological status, oxidative ...
Frans J. Kok, Chen Jiang, D., Zhi Zhang, Feng, Kok, F.J., Ai Guo Ma, Fang Yang, Yong Ye Sun, Xiu Xia Han, Xia Han, Xiu, Feng Zhi Zhang, Dian Chen Jiang, Ye Sun, Yong, Schouten, E.G., Aiguo, M., Yang, Fang, Evert G. Schouten   +15 more
core   +1 more source

Riboflavin Attenuates Influenza Virus Through Cytokine-Mediated Effects on the Diversity of the Gut Microbiota in MAIT Cell Deficiency Mice

Frontiers in Microbiology, 2022
Influenza is a serious respiratory disease that continues to threaten global health. Mucosa-associated invariant T (MAIT) cells use T-cell receptors (TCRs) that recognize microbial riboflavin derived intermediates presented by the major ...
Ying Li, Ying Li, Ying Li, Ying Li, Chun-Wei Shi, Chun-Wei Shi, Chun-Wei Shi, Chun-Wei Shi, Yu-Ting Zhang, Yu-Ting Zhang, Yu-Ting Zhang, Yu-Ting Zhang, Hai-Bin Huang, Hai-Bin Huang, Hai-Bin Huang, Hai-Bin Huang, Yan-Long Jiang, Yan-Long Jiang, Yan-Long Jiang, Yan-Long Jiang, Jian-Zhong Wang, Jian-Zhong Wang, Jian-Zhong Wang, Jian-Zhong Wang, Xin Cao, Xin Cao, Xin Cao, Xin Cao, Nan Wang, Nan Wang, Nan Wang, Nan Wang, Yan Zeng, Yan Zeng, Yan Zeng, Yan Zeng, Gui-Lian Yang, Gui-Lian Yang, Gui-Lian Yang, Gui-Lian Yang, Wen-Tao Yang, Wen-Tao Yang, Wen-Tao Yang, Wen-Tao Yang, Chun-Feng Wang, Chun-Feng Wang, Chun-Feng Wang, Chun-Feng Wang   +47 more
doaj   +1 more source

Maternal vitamin deficiency mimicking multiple acyl-CoA dehydrogenase deficiency on newborn screening

Molecular Genetics and Metabolism Reports, 2021
Background: In infancy multiple acyl-CoA dehydrogenase deficiency (MADD) is commonly a severe inherited metabolic disease caused by genetic defects in electron transfer flavoprotein (ETF) or ETF ubiquinone oxidoreductase.
Gwendolyn Gramer, Georg F. Hoffmann, Julia B. Hennermann   +2 more
doaj   +1 more source