Results 41 to 50 of about 449,947 (286)

A randomised controlled trial investigating the effect of vitamin B12 supplementation on neurological function in healthy older people: the Older People and Enhanced Neurological function (OPEN) study protocol [ISRCTN54195799]. [PDF]

, 2011
BACKGROUND: Vitamin B12 deficiency is common in older people and the prevalence increases with age. Vitamin B12 deficiency may present as macrocytic anaemia, subacute combined degeneration of the spinal cord, or as neuropathy, but is often asymptomatic ...
Allen, Elizabeth, Kerry Mills, Whyte, K, Fletcher, Astrid E, Elbourne, Diana, Richards, Marcus, Ken Whyte, Mills, Kerry, Robert Clarke, Richards, M, Letley, Louise, Dangour, Alan D, Elbourne, D, Mills, K, Ricardo Uauy, Whyte, Ken, Louise Letley, Dangour, AD, Fletcher, AE, Diana Elbourne, Fasey, Nicky, Uauy, Ricardo, Alan D Dangour, Uauy, R, Astrid E Fletcher, Marcus Richards, Clarke, Robert, Clarke, R, Nicky Fasey, Elizabeth Allen, Fasey, N, Allen, E, Letley, L   +32 more
core   +2 more sources

Riboflavin Inhibits Histamine-Dependent Itch by Modulating Transient Receptor Potential Vanilloid 1 (TRPV1)

Frontiers in Molecular Neuroscience, 2021
Riboflavin, also known as vitamin B2, isfound in foods and is used as a dietary supplement. Its deficiency (also called ariboflavinosis) results in some skin lesions and inflammations, such as stomatitis, cheilosis, oily scaly skin rashes, and itchy ...
Kihwan Lee, Young In Choi, Sang-Taek Im, Sung-Min Hwang, Han-Kyu Lee, Jay-Zoon Im, Yong Ho Kim, Sung Jun Jung, Chul-Kyu Park   +8 more
doaj   +1 more source

HEMOPOIESIS IN RIBOFLAVIN-DEFICIENT RATS [PDF]

Blood, 1947
Abstract Leukopenia, granulocytopenia, and, occasionally, anemia develop in rats fed a purified diet deficient in riboflavin. Folic acid (L. casei factor) corrects the leukopenia and granulocytopenia. Riboflavin will prevent all the dyscrasias but will correct only the anemia.
K M, ENDICOTT, A, KORNBERG, M, OTT
openaire   +2 more sources

Suspected outbreak of riboflavin deficiency among populations reliant on food assistance: a case study of drought-stricken Karamoja, Uganda, 2009-2010. [PDF]

PLoS ONE, 2013
BACKGROUND: In 2009, a humanitarian response was launched to address a food security and livelihoods crisis in Karamoja, Uganda. During a polio immunization campaign in mid-August 2009, health workers in Nakapiripit District reported a concern about an ...
Erin K Nichols, Leisel E Talley, Nelly Birungi, Amanda McClelland, Elizabeth Madraa, Agnes B Chandia, Jacqueline Nivet, Rafael Flores-Ayala, Mary K Serdula   +8 more
doaj   +1 more source

Nutritional optic neuropathy induced by riboflavin deficiency from levomepromazine: A case report

Indian Journal of Ophthalmology. Case Reports
Nutritional optic neuropathy (NON) results from a deficiency of essential nutrients required for mitochondrial function. We report a unique case of NON induced by riboflavin deficiency due to levomepromazine treatment for schizophrenia.
Yusuke Hikawa, Shimpei Komoto, Takeshi Morimoto, Yoshiyuki Kitaguchi, Takahiro Fujino, Hiroshi Shimojo, Kohji Nishida   +6 more
doaj   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

SLC22A14 is a mitochondrial riboflavin transporter required for sperm oxidative phosphorylation and male fertility

Cell Reports, 2021
Summary: Ablation of Slc22a14 causes male infertility in mice, but the underlying mechanisms remain unknown. Here, we show that SLC22A14 is a riboflavin transporter localized at the inner mitochondrial membrane of the spermatozoa mid-piece and show by ...
Wenhua Kuang, Jie Zhang, Zhou Lan, R.N.V. Krishna Deepak, Chao Liu, Zhilong Ma, Lili Cheng, Xinbin Zhao, Xianbin Meng, Weihua Wang, Xueying Wang, Lina Xu, Yupei Jiao, Qi Luo, Ziyi Meng, Kehkooi Kee, Xiaohui Liu, Haiteng Deng, Wei Li, Hao Fan, Ligong Chen   +20 more
doaj   +1 more source

Erythrocyte Pathophysiology of Riboflavin deficiency in rats [PDF]

Pathophysiology of erythrocytes from riboflavin-deficient rats has been investigated. Riboflav in-deficiency was produced by feeding a riboflavin-deficient diet ad-libitum to weanling male Wistar specified pathogen-free, albino rats (40-SOg) housed ...
Hassan, FM
core   +1 more source

Study Protocol: Randomised controlled trial to investigate the functional significance of marginal riboflavin status in young women in the UK (RIBOFEM)

BMC Public Health, 2009
Background The functional significance of moderate riboflavin deficiency as it is currently assessed is not well understood. Animal and human studies have suggested a role for riboflavin in the absorption and mobilisation of iron and as such may be ...
Williams Elizabeth A, Mushtaq Sohail, Hill Marilyn HE, Dainty Jack R, Powers Hilary J   +4 more
doaj   +1 more source

Ocular Biomarkers of Riboflavin Transporter Deficiency

, 2023
To describe the clinical presentation with a focus on ocular manifestations and response to riboflavin supplementation of 3 patients with riboflavin transporter deficiency (RTD) caused by mutations in SLC52A2 (SLC52A2-RTD)
Sabrina Bulas, MS; Emma C. Bedoukian, MS, LCGC; Erin C. O\u27Neil, MD; Ian D. Krantz, MD; Sabrina W. Yum, MD; Grant T. Liu, MD; Tomas S. Aleman, MD
core