Results 41 to 50 of about 19,244 (296)
Multiple acyl-CoA dehydrogenase deficiency (MADD) is an inherited metabolic disease caused by a defect in electron transfer flavoprotein alpha (ETFA), ETF beta (ETFB), or ETF dehydrogenase (ETFDH), and riboflavin metabolism disorders have recently been ...
Kenji Yamada+7 more
doaj
Background The functional significance of moderate riboflavin deficiency as it is currently assessed is not well understood. Animal and human studies have suggested a role for riboflavin in the absorption and mobilisation of iron and as such may be ...
Williams Elizabeth A+4 more
doaj +1 more source
Identifying Key Properties That Drive Redox Mediator Activity in Lactiplantibacillus Plantarum
Synthesis and isolation of structurally diverse quinones led to defining key physicochemical properties and biochemical interactions that drive type‐II NADH dehydrogenase (Ndh2)‐dependent extracellular electron transfer activity in Lactiplantibacillus plantarum.
Benjamin T. Blackburn+7 more
wiley +2 more sources
Supramolecular Gels as Active Tools for Reaction Engineering
The unique combination of environments within gels, self‐assembled from low‐molecular‐weight gelators, offers the ability to control reactivity in new ways, achieving unique reaction outcomes, leading to the emerging concept of supramolecular gels as nanoreactors. Smart chemical engineering methods enable the use of such gels to fabricate materials and
David K. Smith
wiley +2 more sources
Flavin adenine dinucleotide rescues the phenotype of frataxin deficiency. [PDF]
BACKGROUND: Friedreich ataxia is a neurodegenerative disease caused by the lack of frataxin, a mitochondrial protein. We previously demonstrated that frataxin interacts with complex II subunits of the electronic transport chain (ETC) and putative ...
Pilar Gonzalez-Cabo+2 more
doaj +1 more source
Riboflavin transporter deficiency (RTD) is a rare genetic disorder characterized by motor, sensory and cranial neuropathy. This childhood-onset neurodegenerative disease is caused by biallelic pathogenic variants in either SLC52A2 or SLC52A3 genes ...
Fiorella Colasuonno+5 more
doaj +1 more source
In this study, we supplemented the diet of breeding sows either with omega‐6 (control) or omega‐3 (experimental) polyunsaturated fatty acids and examined their effects on the antioxidant system and hormone levels of the animals. In the blood levels of molecules indicating oxidative stress we experienced slight changes, but the feeding of omega‐3 fatty ...
Róbert Roszkos+4 more
wiley +1 more source
Estimating high-dimensional intervention effects from observational data [PDF]
We assume that we have observational data generated from an unknown underlying directed acyclic graph (DAG) model. A DAG is typically not identifiable from observational data, but it is possible to consistently estimate the equivalence class of a DAG. Moreover, for any given DAG, causal effects can be estimated using intervention calculus.
arxiv +1 more source
Abstract Flavin co‐factors and other flavin derivatives are traditionally associated with one‐ or two‐electron redox reactions. Flavins also form covalent intermediates with a variety of substrates. While extensive attention has focused on reactions at the C(4a) position of the flavin ring, recent interest has shifted toward the dynamic potential of ...
Tetiana Pavlovska+3 more
wiley +1 more source
Alternatives to riboflavin (vitamin B2) production by recombinant microorganisms are needed in organic poultry production, but are cost-intensive, so that a demand-oriented riboflavin supply is necessary. Details on the riboflavin requirements of organic
C. Lambertz+6 more
doaj