Results 41 to 50 of about 908,771 (315)

Twin Premature Infants With Riboflavin and Biotin Deficiency Presenting With Refractory Lactic Acidosis, Rash, and Multiorgan Failure During Prolonged Parenteral Nutrition

Journal of Investigative Medicine High Impact Case Reports, 2023
We are reporting monochorionic, diamniotic twin premature infants born at 25 weeks and 6 days gestation with riboflavin (vitamin B2) and biotin (vitamin B7) deficiency, while on prolonged total parenteral nutrition (TPN) during vitamin shortage.
Mohammad Amin Adie MD, Maria Martes Gomez DO, Jessica Yom MD, Manuel Durand MD, Fiona Wertheimer DO, Rachel McGowan MS, RD, Shoji Yano MD, PhD, Rangasamy Ramanathan MD   +7 more
doaj   +1 more source

Association of the plasma and tissue riboflavin levels with C20orf54 expression in cervical lesions and its relationship to HPV16 infection. [PDF]

PLoS ONE, 2013
Riboflavin deficiency can cause a variety of metabolic problems that lead to skin and mucosal disorders. Limited evidence suggests that high intake of riboflavin may reduce overall risks of cancer.
Aixingzi Aili, Ayshamgul Hasim, Alimujiang Kelimu, Xia Guo, Batur Mamtimin, Abuliz Abudula, Halmurat Upur   +6 more
doaj   +1 more source

Riboflavin - properties, occurrence and its use in medicine

Pteridines, 2019
Riboflavin is built on an isoalloxazin ring, which contains three sixcarbon rings: benzoic, pyrazine and pyrimidine. Riboflavin is synthesized by some bacteria, but among humans and animals, the only source of flavin coenzymes (FAD, FMN) is exogenous ...
Szczuko Małgorzata, Ziętek Maciej, Kulpa Danuta, Seidler Teresa   +3 more
doaj   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Riboflavin Inhibits Histamine-Dependent Itch by Modulating Transient Receptor Potential Vanilloid 1 (TRPV1)

Frontiers in Molecular Neuroscience, 2021
Riboflavin, also known as vitamin B2, isfound in foods and is used as a dietary supplement. Its deficiency (also called ariboflavinosis) results in some skin lesions and inflammations, such as stomatitis, cheilosis, oily scaly skin rashes, and itchy ...
Kihwan Lee, Young In Choi, Sang-Taek Im, Sung-Min Hwang, Han-Kyu Lee, Jay-Zoon Im, Yong Ho Kim, Sung Jun Jung, Chul-Kyu Park   +8 more
doaj   +1 more source

Suspected outbreak of riboflavin deficiency among populations reliant on food assistance: a case study of drought-stricken Karamoja, Uganda, 2009-2010. [PDF]

PLoS ONE, 2013
BACKGROUND: In 2009, a humanitarian response was launched to address a food security and livelihoods crisis in Karamoja, Uganda. During a polio immunization campaign in mid-August 2009, health workers in Nakapiripit District reported a concern about an ...
Erin K Nichols, Leisel E Talley, Nelly Birungi, Amanda McClelland, Elizabeth Madraa, Agnes B Chandia, Jacqueline Nivet, Rafael Flores-Ayala, Mary K Serdula   +8 more
doaj   +1 more source

Riboflavin transporter deficiency

Definitions, 2020
Riboflavin transporter deficiency (RTD), comprising RTD2 and RTD3 (caused by biallelic pathogenic variants in SLC52A2 and SLC52A3, respectively) is a rare neurologic condition characterized by progressive peripheral and cranial neuronopathy that causes ...
MD Elisa Cali, BSc MSc Natalia Dominik, BSc Andreea Manole, MD Henry Houlden   +3 more
semanticscholar   +1 more source

SLC22A14 is a mitochondrial riboflavin transporter required for sperm oxidative phosphorylation and male fertility

Cell Reports, 2021
Summary: Ablation of Slc22a14 causes male infertility in mice, but the underlying mechanisms remain unknown. Here, we show that SLC22A14 is a riboflavin transporter localized at the inner mitochondrial membrane of the spermatozoa mid-piece and show by ...
Wenhua Kuang, Jie Zhang, Zhou Lan, R.N.V. Krishna Deepak, Chao Liu, Zhilong Ma, Lili Cheng, Xinbin Zhao, Xianbin Meng, Weihua Wang, Xueying Wang, Lina Xu, Yupei Jiao, Qi Luo, Ziyi Meng, Kehkooi Kee, Xiaohui Liu, Haiteng Deng, Wei Li, Hao Fan, Ligong Chen   +20 more
doaj   +1 more source

Mitochondrial Abnormalities in Induced Pluripotent Stem Cells-Derived Motor Neurons from Patients with Riboflavin Transporter Deficiency

Antioxidants, 2020
Riboflavin transporter deficiency (RTD) is a childhood-onset neurodegenerative disorder characterized by sensorineural deafness and motor neuron degeneration.
Fiorella Colasuonno, E. Bertini, M. Tartaglia, C. Compagnucci, S. Moreno   +4 more
semanticscholar   +1 more source

Mitochondrial and Peroxisomal Alterations Contribute to Energy Dysmetabolism in Riboflavin Transporter Deficiency

Oxidative Medicine and Cellular Longevity, 2020
Riboflavin transporter deficiency (RTD) is a childhood-onset neurodegenerative disorder characterized by progressive pontobulbar palsy, sensory and motor neuron degeneration, sensorineural hearing loss, and optic atrophy.
Fiorella Colasuonno, A. Niceforo, Chiara Marioli, Anna Fracassi, Fabrizia Stregapede, K. Massey, M. Tartaglia, E. Bertini, C. Compagnucci, S. Moreno   +9 more
semanticscholar   +1 more source