Results 41 to 50 of about 944,643 (357)

Riboflavin (Vitamin B2) Deficiency Induces Apoptosis Mediated by Endoplasmic Reticulum Stress and the CHOP Pathway in HepG2 Cells

Nutrients, 2022
Riboflavin is an essential micronutrient and a precursor of flavin mononucleotide and flavin adenine dinucleotide for maintaining cell homeostasis. Riboflavin deficiency (RD) induces cell apoptosis.
Bo Zhang, Junfeng Cao, Yongbao Wu, Ke-Xin Gao, M. Xie, Zhengkui Zhou, Jing Tang, Shui-sheng Hou   +7 more
semanticscholar   +1 more source

Demand-oriented riboflavin supply of organic broiler using a feed material from fermentation of Ashbya gossypii

Animal, 2021
Alternatives to riboflavin (vitamin B2) production by recombinant microorganisms are needed in organic poultry production, but are cost-intensive, so that a demand-oriented riboflavin supply is necessary. Details on the riboflavin requirements of organic
C. Lambertz, J. Leopold, S. Ammer, F. Leiber, B. Thesing, C. Wild, K. Damme   +6 more
doaj   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Supplementation of iron alone and combined with vitamins improves haematological status, erythrocyte membrane fluidity and oxidative stress in anaemic pregnant women [PDF]

, 2010
Pregnancy is a condition exhibiting increased susceptibility to oxidative stress, and Fe plays a central role in generating harmful oxygen species. The objective of the present study is to investigate the changes in haematological status, oxidative ...
Aiguo, M., Chen Jiang, D., Kok, F.J., Schouten, E.G., Xia Han, Xiu, Yang, Fang, Ye Sun, Yong, Zhi Zhang, Feng   +7 more
core   +2 more sources

Maternal vitamin deficiency mimicking multiple acyl-CoA dehydrogenase deficiency on newborn screening

Molecular Genetics and Metabolism Reports, 2021
Background: In infancy multiple acyl-CoA dehydrogenase deficiency (MADD) is commonly a severe inherited metabolic disease caused by genetic defects in electron transfer flavoprotein (ETF) or ETF ubiquinone oxidoreductase.
Gwendolyn Gramer, Georg F. Hoffmann, Julia B. Hennermann   +2 more
doaj   +1 more source

Riboflavin-Responsive and -Non-responsive Mutations in FAD Synthase Cause Multiple Acyl-CoA Dehydrogenase and Combined Respiratory-Chain Deficiency [PDF]

, 2017
open48siMultiple acyl-CoA dehydrogenase deficiencies (MADDs) are a heterogeneous group of metabolic disorders with combined respiratory-chain deficiency and a neuromuscular phenotype.

core   +1 more source

Transcriptional profiling of liver in riboflavin-deficient chicken embryos explains impaired lipid utilization, energy depletion, massive hemorrhaging, and delayed feathering

BMC Genomics, 2018
Background A strain of Leghorn chickens (rd/rd), unable to produce a functional riboflavin-binding protein, lays riboflavin-deficient eggs, in which all embryos suddenly die at mid-incubation (days 13-15).
Larry A. Cogburn, Danielle N. Smarsh, Xiaofei Wang, Nares Trakooljul, Wilfrid Carré, Harold B. White   +5 more
doaj   +1 more source

Twin Premature Infants With Riboflavin and Biotin Deficiency Presenting With Refractory Lactic Acidosis, Rash, and Multiorgan Failure During Prolonged Parenteral Nutrition

Journal of Investigative Medicine High Impact Case Reports, 2023
We are reporting monochorionic, diamniotic twin premature infants born at 25 weeks and 6 days gestation with riboflavin (vitamin B2) and biotin (vitamin B7) deficiency, while on prolonged total parenteral nutrition (TPN) during vitamin shortage.
Mohammad Amin Adie MD, Maria Martes Gomez DO, Jessica Yom MD, Manuel Durand MD, Fiona Wertheimer DO, Rachel McGowan MS, RD, Shoji Yano MD, PhD, Rangasamy Ramanathan MD   +7 more
doaj   +1 more source

Association of the plasma and tissue riboflavin levels with C20orf54 expression in cervical lesions and its relationship to HPV16 infection. [PDF]

PLoS ONE, 2013
Riboflavin deficiency can cause a variety of metabolic problems that lead to skin and mucosal disorders. Limited evidence suggests that high intake of riboflavin may reduce overall risks of cancer.
Aixingzi Aili, Ayshamgul Hasim, Alimujiang Kelimu, Xia Guo, Batur Mamtimin, Abuliz Abudula, Halmurat Upur   +6 more
doaj   +1 more source

HEMOPOIESIS IN RIBOFLAVIN-DEFICIENT RATS [PDF]

Blood, 1947
Abstract Leukopenia, granulocytopenia, and, occasionally, anemia develop in rats fed a purified diet deficient in riboflavin. Folic acid (L. casei factor) corrects the leukopenia and granulocytopenia. Riboflavin will prevent all the dyscrasias but will correct only the anemia.
K M, ENDICOTT, A, KORNBERG, M, OTT
openaire   +2 more sources