Results 251 to 260 of about 145,501 (289)

Standardized Diagnostic Assays for Omsk Hemorrhagic Fever Virus. [PDF]

Pathogens
Lee JH, Jung S, Yi H, Chung YS.
europepmc   +1 more source

5′tRF‐GlyGCC Promotes Breast Cancer Progression via LDHA‐Mediated Glycolysis and Macrophage Polarization

Advanced Science, EarlyView.
5’tRF‐GlyGCC promotes breast cancer malignancy by binding to LDHA. This interaction, facilitated by FGFR1 and LDHA phosphorylation, enhances glycolysis. Additionally, 5’tRF‐GlyGCC/LDHA signaling recruits and polarizes macrophages into a pro‐tumor M2 state via CCL7, thus remodeling the tumor microenvironment.
Cheng Yi, Yunqing Lu, Xing Chang, Ying Wang, Jiawang Zhou, Guoyou Xie, Lijun Tao, Zhaotong Wang, Yifan Tian, Lihong Wang, Feng Tang, Yijing Zheng, Xinchen Yue, Jinping Lei, Xiansong Wang, Lichen Ge, Zhuojia Chen, Hongsheng Wang   +17 more
wiley   +1 more source

Transcriptomic profiling to investigate the therapeutic potential and medicinal properties of Momordica cymbalaria. [PDF]

Sci Rep
Krishnakumar H, Nallusamy S, Rajmichael R, Mathimaran A, Pandian CJ, Subramanian G, Jeyaraman J.   +6 more
europepmc   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

Advanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, Dapeng Zhang, Dihua Li, Tian Li, Shimin Yang, Ximo Wang, Xiangyang Yu, Qi Zhang   +16 more
wiley   +1 more source

Feedforward miR-181d degradation modulates population variance of methyl-guanine methyl transferase and temozolomide resistance. [PDF]

Cell Rep
Singh G, Singh S, Mohapatra I, Kim S, Sharma M, Akers J, Nguyen T, Wong E, Moreno MM, Kokkoli E, Vasudevan S, Lawler SE, El-Deiry WS, Gokaslan Z, Chen CC.   +14 more
europepmc   +1 more source

The Evolutionarily Conserved TPM1 Super‐Enhancer Drives Skeletal Muscle Regeneration via Mechanotransduction Signaling

Advanced Science, EarlyView.
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang, Wanyou Feng, Yanyan Yang, Yu Pan, Chaoxia Zou, Leyi Wang, Sanbao Zhang, Yimin Zhao, Yongmei Wu, Jinling Wang, Jianwei Zou, Kehe Cen, Yongwang Zhang, Han Huang, Yurong Xu, Li Zhong, Hailong Gong, Juanru Cheng, Jingyuan Liang, Zihua Zheng, Qinyang Jiang, Jingwei Wei, Hui Li, Minhui Liang, Deshun Shi, Sufang Yang, Yanfei Deng, Yingming Wei   +27 more
wiley   +1 more source

RNase P generated tRF^Ser-GCT promotes fat storage in adipocytes via Adrb2 signaling. [PDF]

J Biol Chem
Shen L, Lei Y, Zhao X, Wang X, Chen D, Wang K, Zhong Y, Liao T, Yang Y, Chen L, Zhao Y, Niu L, Zhou X, Gan M, Zhu L.   +14 more
europepmc   +1 more source

Catalyst‐Free Collagen Filament Crosslinking for Engineering Anisotropic and Mechanically Robust Tissue Scaffolds

Advanced Science, EarlyView.
A bioorthogonal rhodamine/PEG crosslinking strategy is introduced to engineer dense collagen hydrogels with high mechanical resilience and cytocompatibility. Integration with wet‐spinning enables the fabrication of uniaxially aligned, cell‐laden collagen filaments that activate mechanotransductive signaling and support functional muscle regeneration in
JuYeon Kim, Hanjun Hwangbo, ByungJoon Choi, Dogeon Yoon, GeunHyung Kim   +4 more
wiley   +1 more source

Conserved structural topologies in RNase A-like and trypsin-like serine proteases: a sequence-based folding analysis. [PDF]

BMC Mol Cell Biol
Kabir KMA, Takahashi T, Kikuchi T.
europepmc   +1 more source

Carbon-13 Fourier Transform Nuclear Magnetic Resonance, II. Ribonuclease

, 1970
Adam Allerhand, David W. Cochran, David M. Doddrell   +2 more
openalex   +2 more sources