Results 321 to 330 of about 156,401 (384)

A Combined Aptamer Pulldown‐DNAzyme Cleavage Assay for Intact Methicillin Resistant Staphylococcus aureus Cells

Angewandte Chemie International Edition, Accepted Article.
Accurate and convenient detection of methicillin resistant Staphylococcus aureus (MRSA) plays a vital role in determining appropriate antibiotic interventions. Herein, we report the first example combining a DNA aptamer and an RNA‐cleaving DNAzyme (RCD) that bind different protein markers for selective preconcentration and detection of MRSA. An aptamer
Monsur Ali, Abigail Almeida, Dawn White, Alfredo Capretta, John David Brennan   +4 more
wiley   +1 more source

Discovery of bimodal hepatitis B virus ribonuclease H and capsid assembly inhibitors. [PDF]

PLoS Pathog
Bradley DP, Valkner CJ, Li Q, Gasonoo M, Meyers MJ, Prifti GM, Moianos D, Zoidis G, Zlotnick A, Tavis JE.   +9 more
europepmc   +1 more source

RIBONUCLEASE

Journal of Biological Chemistry, 1954
openaire   +3 more sources

Chromosome‐scale reference genome of Pectocarya recurvata, the species with the smallest reported genome size in Boraginaceae

Applications in Plant Sciences, EarlyView.
Abstract Premise Pectocarya recurvata (Boraginaceae, subfamily Cynoglossoideae), a species native to the Sonoran Desert (North America), has served as a model system for a suite of ecological and evolutionary studies. However, no reference genomes are currently available in Cynoglossoideae. A high‐quality reference genome for P.
Poppy C. Northing, Jessie A. Pelosi, D. Lawrence Venable, Katrina M. Dlugosch   +3 more
wiley   +1 more source

Aurora: a fluorescent deoxyribozyme for high-throughput screening. [PDF]

Nucleic Acids Res
Volek M, Kurfürst J, Drexler M, Svoboda M, Srb P, Veverka V, Curtis EA.   +6 more
europepmc   +1 more source

Solvation free energy in governing equations for DNA hybridization, protein-ligand binding, and protein folding. [PDF]

FEBS Open Bio
Harmon C, Bui A, Espejo JM, Gancayco M, Le JM, Rangel J, Eggers DK.   +6 more
europepmc   +1 more source

Ribonuclease inhibitor 1 emerges as a potential biomarker and modulates inflammation and iron homeostasis in sepsis. [PDF]

Sci Rep
Neu C, Beckers C, Frank N, Thomas K, Bartneck M, Simon TP, Mossanen J, Peters K, Singendonk T, Martin L, Marx G, Kraemer S, Zechendorf E.   +12 more
europepmc   +1 more source

The Stem Cell Transcription Factor OCT4 Silences Target DNA Methyltransferase 1 to Strengthen DNA Damage Response in Cisplatin‐Treated Gastric Cancer Cells

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT OCT4 plays a crucial role in the DNA damage response(DDR) mechanism, whereas cisplatin (CDDP) acts as an anti‐tumor agent by inducing DDR. This study aimed to investigate the role of OCT4 in regulating DNA methyltransferase 1 (DNMT1) in CDDP‐treated gastric cancer (GC).
Zhengzheng Yan, Xiaoqian Bu, Haixia Chen, Chongren Ren, Ji Li, Yongjie Wu, Jun Xing   +6 more
wiley   +1 more source

Establishing Methods to Monitor Influenza (A)H5N1 Virus in Dairy Cattle Milk, Massachusetts, USA. [PDF]

Emerg Infect Dis
Stachler E, Gnirke A, McMahon K, Gomez M, Stenson L, Guevara-Reyes C, Knoll H, Hill T, Hill S, Messer KS, Arizti-Sanz J, Albeez F, Curtis E, Samani P, Wewior N, O'Connor DH, Vuyk W, Khoury SE, Schnizlein MK, Rockey NC, Broemmel Z, Mina M, Madoff LC, Wohl S, O'Connor L, Brown CM, Ozonoff A, Park DJ, MacInnis BL, Sabeti PC.   +29 more
europepmc   +1 more source

Transcription‐Replication Conflicts: Unlocking New Frontiers in Cancer

BioEssays, EarlyView.
Transcription‐replication conflicts (TRCs) constitute a major source of genome instability. Such conflicts are regulated by chromatin, its dysfunction causing replication stress, DNA breaks, and mutations frequently found in cancer. We review the molecular basis of TRCs and chromatin regulation and discuss the clinical potential of targeting TRCs as ...
Aleix Bayona‐Feliu, Andrés Aguilera
wiley   +1 more source