Preliminary studies on ribonucleases from Poa pratensis seeds
Acta Societatis Botanicorum Poloniae, 2015 Ribonuclease was extracted from Poa pratensis seeds with 0.1 M acetate buffer, pH 5.1, and then precipitated with alcohol. The enzyme was separated into 5 fractions (I-V) after chromatography on DEAE-cellulose at pH 5.1.
Irena Lorenc-Kubis +1 more
doaj +4 more sources
CHIMIA, 2001 Chemically modified oligonucleotides serve as tools in fundamental research as diagnostic reagents and pharmaceutical compounds. Various chemical groups can nowadays be linked to oligonucleotides, In particular, synthetic constructs of ...
Robert Häner
doaj +3 more sources
When Ribonucleases Come into Play in Pathogens: A Survey of Gram-Positive Bacteria [PDF]
International Journal of Microbiology, 2012 It is widely acknowledged that RNA stability plays critical roles in bacterial adaptation and survival in different environments like those encountered when bacteria infect a host.
Brian C. Jester +2 more
doaj +2 more sources
A Comparative Overview of the Role of Human Ribonucleases in Nonsense-Mediated mRNA Decay. [PDF]
Genes (Basel)Eukaryotic cells possess surveillance mechanisms that detect and degrade defective transcripts. Aberrant transcripts include mRNAs with a premature termination codon (PTC), targeted by the nonsense-mediated decay (NMD) pathway, and mRNAs lacking a ...
da Costa PJ +8 more
europepmc +2 more sources
Colletotrichum fructicola co-opts cytotoxic ribonucleases that antagonize host competitive microorganisms to promote infection [PDF]
mBioPhytopathogens secrete numerous molecules into the environment to establish a microbial niche and facilitate host infection. The phytopathogenic fungus Colletotrichum fructicola, which causes pear anthracnose, can colonize different plant tissues like ...
Chunhao Wang +6 more
doaj +2 more sources
Strengths and Challenges of Secretory Ribonucleases as AntiTumor Agents
Pharmaceutics, 2021 Approaches to develop effective drugs to kill cancer cells are mainly focused either on the improvement of the currently used chemotherapeutics or on the development of targeted therapies aimed at the selective destruction of cancer cells by steering ...
Jessica Castro +2 more
exaly +3 more sources
Defining the networks that connect RNase III and RNase J-mediated regulation of primary and specialized metabolism in Streptomyces venezuelae [PDF]
Journal of BacteriologyRNA metabolism involves coordinating RNA synthesis with RNA processing and degradation. Ribonucleases play fundamental roles within the cell, contributing to the cleavage, modification, and degradation of RNA molecules, with these actions ensuring ...
Meghan A. D. Pepler +3 more
doaj +2 more sources
Specific Targeting of Recombinant Human Pancreatic Ribonuclease 1 using Gonadotropin-Releasing Hormone Targeting Peptide toward Gonadotropin-Releasing Hormone Receptor-Positive Cancer Cells [PDF]
Iranian Journal of Medical Sciences, 2021 Background: Targeted drug delivery is a novel method to specifically deliver anticancer therapeutics to tumor sites. Gonadotropin-releasing hormone (GnRH) is a decapeptide, and its target binding property has attracted attention as a means of targeted ...
Amir Maleksabet +4 more
doaj +1 more source
Agronomy, 2021 Germination and seedling development are crucial phases in a plant’s life cycle with economical and agronomical implications. The RNA quality in seeds is linked to seed viability, being an important agronomic trait since this leads to a loss in ...
Mercedes Diaz-Baena +4 more
doaj +1 more source
The reaction of ribonuclease inhibitor with modified ribonucleases [PDF]
Biochemical Journal, 1966 1. The effect of chemical modification of ribonuclease on its reaction with ribonuclease inhibitor has been studied. 2. Removal of free amino groups from the enzyme with nitrous acid or by acetylation did not affect the reaction. Some changes altered the stoicheiometry of the reaction and ribonuclease S was found to be inhibited linearly by increasing ...
J S, Roth, D, Hurley
openaire +2 more sources