Results 31 to 40 of about 21,043 (311)

CRYSTALLINE RIBONUCLEASE [PDF]

open access: yesJournal of General Physiology, 1940
1. A crystalline enzyme capable of digesting yeast nucleic acid has been isolated from fresh beef pancreas. 2. The enzyme called "ribonuclease" is a soluble protein of albumin type. Its molecular weight is about 15,000. Its isoelectric point is in the region of pH 8.0. 3.
openaire   +2 more sources

Immune Modulation by Human Secreted RNases at the Extracellular Space

open access: yesFrontiers in Immunology, 2018
The ribonuclease A superfamily is a vertebrate-specific family of proteins that encompasses eight functional members in humans. The proteins are secreted by diverse innate immune cells, from blood cells to epithelial cells and their levels in our body ...
Lu Lu   +3 more
doaj   +1 more source

Streptomyces RNases – Function and impact on antibiotic synthesis

open access: yesFrontiers in Microbiology, 2023
Streptomyces are soil dwelling bacteria that are notable for their ability to sporulate and to produce antibiotics and other secondary metabolites. Antibiotic biosynthesis is controlled by a variety of complex regulatory networks, involving activators ...
George H. Jones
doaj   +1 more source

The role of RNA regulators, quorum sensing and c‐di‐GMP in bacterial biofilm formation

open access: yesFEBS Open Bio, 2023
Biofilms provide an ecological advantage against many environmental stressors, such as pH and temperature, making it the most common life‐cycle stage for many bacteria.
Manuel Condinho   +5 more
doaj   +1 more source

Cleavage of pyrene-stabilized RNA bulge loops by trans-(±)-cyclohexane-1,2-diamine [PDF]

open access: yes, 2012
Chemical agents that cleave HIV genome can be potentially used for anti-HIV therapy. In this report, the cleavage of the upper stem-loop region of HIV-1 TAR RNA was studied in a variety of buffers containing organic catalysts.
Sejal Patel   +3 more
core   +2 more sources

The 5'-3' exoribonuclease pacman is required for epithelial sheet sealing in Drosophila and genetically interacts with the phosphatase puckered [PDF]

open access: yes, 2008
Background information. Ribonucleases have been well studied in yeast and bacteria, but their biological significance to developmental processes in multicellular organisms is not well understood.
Browne, Cathy   +7 more
core   +2 more sources

Ribonuclease and Ribonuclease-Inhibitors Among Higher Plants

open access: yesExperimental Biology and Medicine, 1955
Summary1) Aqueous extracts prepared from 41 common plants were tested for ribonuclease activity and for capacity to inhibit pancreatic ribonuclease. Extracts of 5 plants (Phlox sp., Lathyrus sp., Asclepias syriaca, Allium sp. and Yucca filamentosa) were found capable of degrading ribonucleic acid, and these plants appear to constitute new sources of ...
A W, BERNHEIMER, J M, STEELE
openaire   +2 more sources

Ribonucleases with Antiproliferative Properties: Molecular Biological and Biochemical Characteristics

open access: yesКлиническая онкогематология, 2016
The article dwells on ribonucleases (RNAses) whose cytotoxic activity depends on the enzymatic activity, i.e. the ability to catalyze the cleavage of phosphodiester bonds of RNA.
Vadim Sergeevich Pokrovskii   +3 more
doaj   +1 more source

Magnetite Nanoparticles Functionalized with RNases against Intracellular Infection of Pseudomonas aeruginosa

open access: yesPharmaceutics, 2020
Current treatments against bacterial infections have severe limitations, mainly due to the emergence of resistance to conventional antibiotics. In the specific case of Pseudomonas aeruginosa strains, they have shown a number of resistance mechanisms to ...
Nathaly Rangel-Muñoz   +8 more
doaj   +1 more source

First biochemical characterization of a novel ribonuclease from wild mushroom Amanita hemibapha [PDF]

open access: yes, 2012
A 45-kDa ribonuclease (RNase) was purified from dried fruiting bodies of the wild mushroom Amanita hemibapha. It was adsorbed on DEAE-cellulose, S-sepharose, and finally purified on Superdex 75. The RNase exhibited maximal RNase activity at pH 5 and in a
Bo Wang   +4 more
core   +1 more source

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