Results 21 to 30 of about 14,217 (304)
CATALYTIC PROPERTIES OF THE EUKARYOTIC EXOSOME [PDF]
The eukaryotic exosome complex is built around the backbone of a 9‑subunit ring similar to phosporolytic ribonucleases such as RNase PH and polynucleotide phosphorylase (PNPase).
María Eugenia Gas López +13 more
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Two glycoproteidic acid RNases (RNase I and RNase II) were obtained and purified from the seeds of Dactylis glomerata by extraction with acetate buffer, fractionation with ammonium sulfate, ion-exchange chromatography on DEAE-cellulose, DEAE-Sphadex ...
Janina Wiśniowska +1 more
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“Life is short, and art is long”: RNA degradation in cyanobacteria and model bacteria
RNA turnover plays critical roles in the regulation of gene expression and allows cells to respond rapidly to environmental changes. In bacteria, the mechanisms of RNA turnover have been extensively studied in the models Escherichia coli and Bacillus ...
Ju‐Yuan Zhang +2 more
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Tumour progression is accompanied by rapid cell proliferation, loss of differentiation, the reprogramming of energy metabolism, loss of adhesion, escape of immune surveillance, induction of angiogenesis, and metastasis.
Nadezhda Mironova, Valentin Vlassov
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Hirsutellin A: A Paradigmatic Example of the Insecticidal Function of Fungal Ribotoxins
The fungal pathogen Hirsutella thompsonii produces an insecticidal protein named hirsutellin A (HtA), which has been described to be toxic to several species of mites, insect larvae, and cells.
Álvaro Martínez del Pozo +6 more
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Streptomyces RNases – Function and impact on antibiotic synthesis
Streptomyces are soil dwelling bacteria that are notable for their ability to sporulate and to produce antibiotics and other secondary metabolites. Antibiotic biosynthesis is controlled by a variety of complex regulatory networks, involving activators ...
George H. Jones
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The role of RNA regulators, quorum sensing and c‐di‐GMP in bacterial biofilm formation
Biofilms provide an ecological advantage against many environmental stressors, such as pH and temperature, making it the most common life‐cycle stage for many bacteria.
Manuel Condinho +5 more
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The Immunomodulatory and Antimicrobial Properties of the Vertebrate Ribonuclease A Superfamily
The Ribonuclease A Superfamily is composed of cationic peptides that are secreted by immune cells and epithelial tissues. Although their physiological roles are unclear, several members of the vertebrate Ribonuclease A Superfamily demonstrate ...
Laura Schwartz +3 more
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Biological Activities of Secretory RNases: Focus on Their Oligomerization to Design Antitumor Drugs
Ribonucleases (RNases) are a large number of enzymes gathered into different bacterial or eukaryotic superfamilies. Bovine pancreatic RNase A, bovine seminal BS-RNase, human pancreatic RNase 1, angiogenin (RNase 5), and amphibian onconase belong to the ...
Giovanni Gotte, Marta Menegazzi
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Current treatments against bacterial infections have severe limitations, mainly due to the emergence of resistance to conventional antibiotics. In the specific case of Pseudomonas aeruginosa strains, they have shown a number of resistance mechanisms to ...
Nathaly Rangel-Muñoz +8 more
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