Results 11 to 20 of about 21,043 (311)

Structure-guided discovery of ancestral CRISPR-Cas13 ribonucleases [PDF]

Science
Peter Yoon, Kenneth Loi, Arushi Lahiri
exaly   +2 more sources

Preliminary studies on ribonucleases from Poa pratensis seeds

Acta Societatis Botanicorum Poloniae, 2015
Ribonuclease was extracted from Poa pratensis seeds with 0.1 M acetate buffer, pH 5.1, and then precipitated with alcohol. The enzyme was separated into 5 fractions (I-V) after chromatography on DEAE-cellulose at pH 5.1.
Irena Lorenc-Kubis, Bronisława Morawiecka   +1 more
doaj   +1 more source

Isolation, Characterization, and Biocompatibility of Bisporitin, a Ribotoxin-like Protein from White Button Mushroom (Agaricus bisporus)

Biomolecules, 2023
White button mushroom (Agaricus bisporus (J.E. Lange) Imbach) is one of the widely consumed edible mushrooms. Indeed, A. bisporus fruiting bodies are a rich source of nutrients and bioactive molecules.
Sara Ragucci, Hafiza Zumra Fatima Hussain, Andrea Bosso, Nicola Landi, Angela Clemente, Paolo Vincenzo Pedone, Elio Pizzo, Antimo Di Maro   +7 more
doaj   +1 more source

Adenovirus-mediated hPNPase(old-35) gene transfer as a therapeutic strategy for neuroblastoma [PDF]

, 2009
Current treatment options for neuroblastoma fail to eradicate the disease in the majority of high-risk patients, clearly mandating development of innovative therapeutic strategies. Gene therapy represents a promising approach for reversing the neoplastic
Ardelt, Arnold, Beck, Benito, Brodeur, Chan, Cinatl, Cinatl, D'Alessio, Hellemans, Holmes, Jasty, Kotchetkov, Lebedeva, Lebedeva, Leszczyniecka, Leszczyniecka, Maris, McConville, Michaelis, Pattyn, Pattyn, Ross, Sarkar, Sarkar, Sarkar, Sarkar, Sarkar, Sarkar, Su, Tweddle, Van Maerken, Vandesompele, Vandesompele, Vasandani, Vasandani, Youle, Young   +37 more
core   +2 more sources

Analogs of the Catechol Derivative Dynasore Inhibit HIV-1 Ribonuclease H, SARS-CoV-2 nsp14 Exoribonuclease, and Virus Replication

Viruses, 2023
Viral replication often depends on RNA maturation and degradation processes catalyzed by viral ribonucleases, which are therefore candidate targets for antiviral drugs.
Abhishek Asthana, Angela Corona, Woo-Jin Shin, Mi-Jeong Kwak, Christina Gaughan, Enzo Tramontano, Jae U. Jung, Rainer Schobert, Babal Kant Jha, Robert H. Silverman, Bernhard Biersack   +10 more
doaj   +1 more source

Detection of MicroRNAs in Dried Serum Blots [PDF]

, 2010
MicroRNAs are short RNAs which can be utilized as biomarkers for a variety of conditions. They are detectable in serum, and changes in the levels of circulating microRNAs have been associated with different diseases.
Reema Mallick, Sai Yendamuri, Santosh K. Patnaik   +2 more
core   +2 more sources

DNA-based S-genotyping of Japanese plum and pluot cultivars to clarify incompatibility relationships [PDF]

, 2007
Diploid japanese plum (Prunus salicina Lindl.) cultivars are commonly self-incompatible. To date, 14 incompatibility alleles (S-alleles) have been identified and labeled with alphabetical (S-a-S-n) and 5 with numeric codes (S-1, S-3-S-6).
Halász, Júlia, Hegedűs, Attila, Pedryc, Andrzej, Szabó, Zoltán   +3 more
core   +1 more source

Human Antimicrobial RNases Inhibit Intracellular Bacterial Growth and Induce Autophagy in Mycobacteria-Infected Macrophages

Frontiers in Immunology, 2019
The development of novel treatment against tuberculosis is a priority global health challenge. Antimicrobial proteins and peptides offer a multifaceted mechanism suitable to fight bacterial resistance.
Lu Lu, Javier Arranz-Trullén, Javier Arranz-Trullén, Guillem Prats-Ejarque, David Pulido, Sanjib Bhakta, Ester Boix   +6 more
doaj   +1 more source

The effect of sheltered load on reproduction in Solanum carolinense, a species with variable self-incompatibility [PDF]

, 2009
In previous studies, we have investigated the strength of self-incompatibility (SI) in Solanum carolinense, a highly successful weed with a fully functional SI system that inhabits early successional and other disturbed habitats.
Keser, L.H., Mena-Ali, J.I., Stephenson, A.G.   +2 more
core   +2 more sources

Cationic poly(amidoamine) promotes cytosolic delivery of bovine RNase A in melanoma cells, while maintaining its cellular toxicity [PDF]

, 2015
Ribonucleases are known to cleave ribonucleic acids, inducing cell death. RNase A, a member of the ribonuclease family, generally displayed poor in vitro activity. This has been attributed to factors such as low intracellular delivery.
Akinc, Almeida, Berisio, Cafaro, Chao, Cohen, Coué, Coué, De Lorenzo, Di Donato, Ding, Dubois, Ellis, Ercole, Ferruti, Foglia, Futami, Futami, Futami, Hattori, Hunter, Iversen, Ivinova, Karayianni, Larsericsdotter, Lavignac, Lavignac, Lavignac, Ledoux, Lee, Leich, Leland, Lienqueo, Liu, Lo, Mahn, Matousek, Mattison, Nicholson, Parhamifar, Parhamifar, Pattrick, Peng, Pfeil, Pouckova, Pouckova, Richardson, Romanini, Sasisanker, Saxena, Sedlak, Seyrek, Smith, Tribet, van de Weert, Vottariello, Wang, Wilson, Xia, Yeo, Zhang   +60 more
core   +1 more source