Results 191 to 200 of about 22,541 (295)

Action of dimeric ribonucleases on double‐stranded RNA [PDF]

, 1972
Giuseppe D’Alessio, S Zofra, Massimo Libonati   +2 more
openalex   +1 more source

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

Involvement of RNase J in CRISPR RNA maturation in the cyanobacterium <i>Synechocystis</i> sp. PCC 6803. [PDF]

Microlife
Bilger R, Drepper F, Knapp B, Berndt T, Landerer H, Putzer H, Huesgen PF, Hess WR.   +7 more
europepmc   +1 more source

Molecular Cloning of cDNAs Encoding Ribonuclease-related Proteins inNicotiana glutinosaLeaves, as Induced in Response to Wounding or to TMV-infection [PDF]

, 2002
Naomi Kurata, Tohru Kariu, Shin Kawano, Makoto Kimura   +3 more
openalex   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Potential function of miRNA as a diagnostic biomarker for human ovarian cancer. [PDF]

Discov Oncol
Liu F, An Z, Tang C, Han X.
europepmc   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Technologies for Targeted RNA Degradation and Induced RNA Decay. [PDF]

Chem Rev
Mikutis S, Bernardes GJL.
europepmc   +1 more source

Further Studies on the Alkylation of the Histidine Residues at the Active Site of Pancreatic Ribonuclease

, 1968
Mengjie Lin, William H. Stein, Sara Moore   +2 more
openalex   +1 more source

A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines

Advanced Science, EarlyView.
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin, Chenchen Zhang, Jiahao Li, Kun Huang, Min Qiu   +4 more
wiley   +1 more source