Results 211 to 220 of about 121,107 (346)

The quest for the best target genes for RNAi‐mediated pest control

Insect Molecular Biology, EarlyView.
A major challenge for RNAi mediated pest control is the identification of the most effective RNAi target genes from the pool of ~37% of all genes that are essential. Effective RNAi target genes are predominantly highly conserved genes serving basic cellular functions such as protein degradation.
Doga Cedden, Gregor Bucher
wiley   +1 more source

Amyotrophic lateral sclerosis caused by TARDBP mutations: from genetics to TDP-43 proteinopathy. [PDF]

Lancet Neurol
Balendra R, Sreedharan J, Hallegger M, Luisier R, Lashuel HA, Gregory JM, Patani R.   +6 more
europepmc   +1 more source

Immunoelectron microscope visualization of nuclear ribonucleoprotein antigens within spread transcription complexes. [PDF]

, 1986
Stanislav Fakan, George P. Leser, Terence E. Martin   +2 more
openalex   +1 more source

Shorter Telomeres and Faster Telomere Attrition in Individuals With Five Syndromic Forms of Intellectual Disability: A Systematic Review and Meta‐Analysis

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background People with intellectual disability suffer complex challenges due to adaptive functioning limitations, high rates of chronic diseases and shortened lifespans compared with the general population. Telomere shortening is a hallmark of ageing, and short telomeres are linked to neurological disorders.
Sarah M. Hanley, Nicola S. Schutte, Jessica Bellamy, Joshua Denham   +3 more
wiley   +1 more source

Proteomic Analysis of Transbronchial Biopsies to Discover Novel Biomarkers for Early Identification of Chronic Lung Allograft Dysfunction. [PDF]

Transplant Direct
Tahmasbpour E, Philp A, Sivasubramaniam V, Thomson C, Plit M, Ravipati A, Raftery M, Darley D.   +7 more
europepmc   +1 more source

Small nuclear RNA transcription and ribonucleoprotein assembly in early Xenopus development. [PDF]

, 1983
Douglass J. Forbes, Thomas B. Kornberg, Marc W. Kirschner   +2 more
openalex   +1 more source

Alternative Splicing Regulation in Metabolic Disorders

Obesity Reviews, EarlyView.
ABSTRACT Alternative splicing (AS) is a fundamental mechanism for enhancing transcriptome diversity and regulating gene expression, crucial for various cellular processes and the development of complex traits. This review examines the role of AS in metabolic disorders, including obesity, weight loss, dyslipidemias, and metabolic syndrome.
Dorota Kaminska
wiley   +1 more source

Attribution of psychiatric manifestations to systemic lupus erythematosus in Chinese patients: A retrospective study. [PDF]

World J Psychiatry
Geng WQ, Yang XX, Cao JY, Zhang SZ, Jiang YN, Wei J.   +5 more
europepmc   +1 more source

Fractionation of HeLa cell nuclear extracts reveals minor small nuclear ribonucleoprotein particles. [PDF]

, 1987
A Krämer
openalex   +1 more source

Host‐induced gene silencing of the amino acid biosynthesis gene acetolactate synthase of Phytophthora infestans caused strong enhanced late blight resistance of potato in the field

Plant Biotechnology Journal, EarlyView.
Summary Late blight caused by Phytophthora infestans is the most serious disease of potatoes. Here we present the effectiveness of the host‐induced gene silencing (HIGS) technology against an amino acid biosynthesis gene of the pathogen to increase the resistance against the plant‐infecting oomycete in the field.
Nora Temme, Tobias Haehre, Clarissa Boyher, Lydia Hoppe, Colin Davenport, Zach Stumo, Kai Prenzler, Anja Maeser, Maike Pflugmacher, Kerstin Koch, Dietmar J. Stahl   +10 more
wiley   +1 more source