Personalized Follow Up and Genetic Diagnosis Update of <i>FMR1</i>-Related Conditions: A Change in Diagnosis, Prognosis and Expectations. [PDF]
Roche-Martínez A +5 more
europepmc +1 more source
Protoplast‐Based Functional Genomics and Genome Editing: Progress, Challenges and Applications
ABSTRACT Protoplast‐based systems provide a powerful and versatile platform for exploring how plants sense and respond to their environment. By enabling the direct delivery of proteins, DNA, and RNA into plant cells after cell wall removal, this approach facilitates precise molecular dissection of signaling, stress adaptation, and gene regulation ...
Jo‐Wei Allison Hsieh +8 more
wiley +1 more source
HNRNPA2B1 confers immune escape of non-small cell lung cancer through targeting lactate/ferroptosis. [PDF]
Zhang Y, Chen Y, Zhang J, Du X, Huang C.
europepmc +1 more source
Evolution of H5N1 Cross‐Species Transmission: Adaptive Mutations Driving Avian‐to‐Human Infection
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Wenxin Man +7 more
wiley +1 more source
Microinflammation-Driven Gene Expression Dynamics in the Pathogenesis of Metabolic Disorders and Cancer. [PDF]
Cadungog MEGT, Tayo LL.
europepmc +1 more source
RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang +6 more
wiley +1 more source
Detection of tomato brown rugose fruit virus through CRISPR-Cas12a and CRISPR-Cas9 systems. [PDF]
Besati M +7 more
europepmc +1 more source
We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Yoshio Goshima +9 more
wiley +1 more source
Integrated Bioinformatics Analysis of Differentially Expressed RNA-Binding Proteins in Human Gliomas. [PDF]
Haque S +4 more
europepmc +1 more source

