Results 51 to 60 of about 167,361 (378)
Neural Regeneration Research, 2023 Heterogenous nuclear ribonucleoprotein G is down-regulated in the spinal cord of the Tg(SOD1*G93A)1Gur (TG) amyotrophic lateral sclerosis mouse model.
Fang Yang +4 more
doaj +1 more source
Genome editing in maize directed by CRISPR–Cas9 ribonucleoprotein complexes
Nature Communications, 2016 Targeted DNA double-strand breaks have been shown to significantly increase the frequency and precision of genome editing. In the past two decades, several double-strand break technologies have been developed.
S. Svitashev +4 more
semanticscholar +1 more source
cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins [PDF]
, 2008 mRNA localization is a conserved post-transcriptional process crucial for a variety of systems. Although several mechanisms have been identified, emerging evidence suggests that most transcripts reach the protein functional site by moving along ...
AMORESANO, ANGELA +5 more
core +1 more source
bioRxiv, 2020 CRISPR/Cas9 gene editing is a powerful technology to study the genetics of rising model organisms, such as the jewel wasp Nasonia vitripennis. However, current methods involving embryonic microinjection of CRISPR reagents are challenging.
Duverney Chaverra-Rodriguez +5 more
semanticscholar +1 more source
Binding of RNA by the Nucleoproteins of Influenza Viruses A and B
Viruses, 2016 This paper describes a biochemical study for making complexes between the nucleoprotein of influenza viruses A and B (A/NP and B/NP) and small RNAs (polyUC RNAs from 5 to 24 nucleotides (nt)), starting from monomeric proteins.
Alice Labaronne +5 more
doaj +1 more source
Direct Cytosolic Delivery of CRISPR/Cas9-Ribonucleoprotein for Efficient Gene Editing.
ACS Nano, 2017 Genome editing through the delivery of CRISPR/Cas9-ribonucleoprotein (Cas9-RNP) reduces unwanted gene targeting and avoids integrational mutagenesis that can occur through gene delivery strategies.
R. Mout +6 more
semanticscholar +1 more source
Ribonucleoprotein multimers and their functions [PDF]
Critical Reviews in Biochemistry and Molecular Biology, 2010 Ribonucleoproteins (RNPs) play key roles in many cellular processes and often function as RNP enzymes. Similar to proteins, some of these RNPs exist and function as multimers, either homomeric or heteromeric. While in some cases the mechanistic function of multimerization is well understood, the functional consequences of multimerization of other RNPs ...
Franziska, Bleichert, Susan J, Baserga
openaire +2 more sources
Журнал микробиологии, эпидемиологии и иммунобиологии, 2019 Aim. Isolation of ribonucleoprotein (RNP) of an attenuated rabies virus, develop schemes for immunizing animals with RNP-based preparations and determine the most effective scheme that allows obtaining serum with a high antibody titer to the RNP ...
Yu. K. Gavrilova +8 more
doaj +1 more source
Functional Bias and Spatial Organization of Genes in Mutational Hot and Cold Regions in the Human Genome [PDF]
, 2004 The neutral mutation rate is known to vary widely along human chromosomes, leading to mutational hot and cold regions. We provide evidence that categories of functionally-related genes reside preferentially in mutationally hot or cold regions, the size ...
Chuang, Jeffrey H., Li, Hao
core +5 more sources
Nature BiotechnologyPrime editing enables precise installation of genomic substitutions, insertions and deletions in living systems. Efficient in vitro and in vivo delivery of prime editing components, however, remains a challenge.
Meirui An +8 more
semanticscholar +1 more source