Effect of homopolyribonucleotides on messenger ribonucleoprotein particles [PDF]
Nucleic Acids Research, 1977 A discrete set of polypeptides copurify with and appear to be specifically attached to mRNA from polysomes of eukaryotic cells. This report describes the effect of homopolyribonucleotides on mRNA-protein complexes separated from ribosome subunits by oligo(dT)-cellulose chromatography.
Bo Sundquist, Torgny Persson
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Structures of ribonucleoprotein particle modification enzymes. [PDF]
Q Rev Biophys, 2011 AbstractSmall nucleolar and Cajal body ribonucleoprotein particles (RNPs) are required for the maturation of ribosomes and spliceosomes. They consist of small nucleolar RNA or Cajal body RNA combined with partner proteins and represent the most complex RNA modification enzymes.
Liang B, Liang B, Li H.
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Formation of Ribosomes from Precursor Ribonucleoprotein Particles [PDF]
Journal of Bacteriology, 1965 Sypherd, Paul S. (University of California, San Diego). Formation of ribosomes from precursor ribonucleoprotein particles. J. Bacteriol. 90: 411–417. 1965.—Amino acid deprivation of a “relaxed” mutant leads to the accumulation of ribonucleoprotein particles.
Paul S. Sypherd
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Ribonucleoprotein Particles in HeLa Cells [PDF]
European Journal of Biochemistry, 1972 We have investigated some properties of a class of cytoplasmic ribonucleoprotein particles in HeLa cells. After 3.5 h of labelling in the presence of 0.04 μg/ml actinomycin D to inhibit rRNA synthesis, about 20% of the newly synthesized cytoplasmic RNA, that sediments faster than 7 S, is contained in two types of particles sedimenting at 45 S and 30 S ...
Gerd Wengler +2 more
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The assembly of a spliceosomal small nuclear ribonucleoprotein particle. [PDF]
Nucleic Acids Res, 2008 The U1, U2, U4, U5 and U6 small nuclear ribonucleoprotein particles (snRNPs) are essential elements of the spliceosome, the enzyme that catalyzes the excision of introns and the ligation of exons to form a mature mRNA. Since their discovery over a quarter century ago, the structure, assembly and function of spliceosomal snRNPs have been extensively ...
Patel SB, Bellini M.
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Characterization of L1-Ribonucleoprotein Particles [PDF]
, 2016 The LINE-1 retrotransposon (L1) encodes two proteins, ORF1p and ORF2p, which bind to the L1 RNA in cis, forming a ribonucleoprotein (RNP) complex that is critical for retrotransposition. Interactions with both permissive and repressive host factors pervade every step of the L1 life cycle.
Kathleen H. Burns +8 more
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An intimate view of a spliceosome component
eLife, 2015 A high-resolution structure reveals how the ribonucleoprotein particle called U1 snRNP engages with 5′ splice sites.
Timothy W Nilsen
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Vaults. III. Vault ribonucleoprotein particles open into flower-like structures with octagonal symmetry. [PDF]
, 1991 The structure of rat liver vault ribonucleoprotein particles was examined using several different staining techniques in conjunction with EM and digestion with hydrolytic enzymes.
Chugani, DC +3 more
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Mitochondrial ribosome assembly in Neurospora. Structural analysis of mature and partially assembled ribosomal subunits by equilibrium centrifugation in CsCl gradients [PDF]
, 1982 In Neurospora, one protein associated with the mitochondrial small ribosomal subunit (S-5, Mr 52,000) is synthesized intramitochondrially and is assumed to be encoded by mtDNA.
Lambowitz, Alan M., LaPolla, Robert J.
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Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]
, 2013 Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Bottcher, B. +4 more
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