Results 1 to 10 of about 95,096 (120)
Structural studies of protein–nucleic acid complexes: A brief overview of the selected techniques
Computational and Structural Biotechnology Journal, 2023 Protein–nucleic acid complexes are involved in all vital processes, including replication, transcription, translation, regulation of gene expression and cell metabolism.
Kamil Szpotkowski +2 more
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Frontiers in Genome Editing, 2022 Delivery of genome editing reagents using CRISPR-Cas ribonucleoproteins (RNPs) transfection offers several advantages over plasmid DNA-based delivery methods, including reduced off-target editing effects, mitigation of random integration of non-native ...
Raviraj Banakar +15 more
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Proteins Rpr2 and Pop3 increase the activity and thermal stability of yeast RNase P
RNA Biology, 2023 RNA-based enzyme RNase P is a ribonucleoprotein complex responsible primarily for 5’-maturation of tRNAs. S. cerevisiae RNase P comprises a catalytic RNA component and nine proteins. The assembly and maturation of S.
Anna Perederina +2 more
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Approaches to Identify and Characterise the Post-Transcriptional Roles of lncRNAs in Cancer
Non-Coding RNA, 2021 It is becoming increasingly evident that the non-coding genome and transcriptome exert great influence over their coding counterparts through complex molecular interactions.
Jean-Michel Carter +4 more
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Viruses, 2021 An evolutionary arms race has been ongoing between retroviruses and their primate hosts for millions of years. Within the last century, a zoonotic transmission introduced the Human Immunodeficiency Virus (HIV-1), a retrovirus, to the human population ...
Kevin M. Rose +6 more
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Unknown Areas of Activity of Human Ribonuclease Dicer: A Putative Deoxyribonuclease Activity
Molecules, 2020 The Dicer ribonuclease plays a crucial role in the biogenesis of small regulatory RNAs (srRNAs) by processing long double-stranded RNAs and single-stranded hairpin RNA precursors into small interfering RNAs (siRNAs) and microRNAs (miRNAs), respectively ...
Marta Wojnicka +2 more
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Frontiers in Genome Editing, 2022 Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) mediated genome editing is a powerful approach for crop improvement. Traditional transformation methods based on plasmid delivery pose concerns associated with transgene integration and ...
Yingxiao Zhang +11 more
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Budding of a Retrovirus: Some Assemblies Required
Viruses, 2020 One of the most important steps in any viral lifecycle is the production of progeny virions. For retroviruses as well as other viruses, this step is a highly organized process that occurs with exquisite spatial and temporal specificity on the cellular ...
Kevin M. Rose +2 more
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The World of Stable Ribonucleoproteins and Its Mapping With Grad-Seq and Related Approaches
Frontiers in Molecular Biosciences, 2021 Macromolecular complexes of proteins and RNAs are essential building blocks of cells. These stable supramolecular particles can be viewed as minimal biochemical units whose structural organization, i.e., the way the RNA and the protein interact with each
Milan Gerovac +4 more
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Application of CRISPR/Cas9 Tools for Genome Editing in the White-Rot Fungus Dichomitus squalens
Biomolecules, 2021 Dichomitus squalens is an emerging reference species that can be used to investigate white-rot fungal plant biomass degradation, as it has flexible physiology to utilize different types of biomass as sources of carbon and energy. Recent comparative (post-
Joanna E. Kowalczyk +2 more
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