Results 31 to 40 of about 33,782 (294)

Nucleocytoplasmic Shuttling of Influenza A Virus Proteins

Viruses, 2015
Influenza viruses transcribe and replicate their genomes in the nuclei of infected host cells. The viral ribonucleoprotein (vRNP) complex of influenza virus is the essential genetic unit of the virus.
Jing Li, Meng Yu, Weinan Zheng, Wenjun Liu   +3 more
doaj   +1 more source

Functional insights from a surface antigen mRNA-bound proteome

eLife, 2021
Trypanosoma brucei is the causative agent of human sleeping sickness. The parasites’ variant surface glycoprotein (VSG) enables them to evade adaptive immunity via antigenic variation. VSG comprises 10% of total cell protein and the high stability of VSG
Larissa Melo do Nascimento, Franziska Egler, Katharina Arnold, Nina Papavasiliou, Christine Clayton, Esteban Erben   +5 more
doaj   +1 more source

Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae. [PDF]

, 1994
To study the functions of heterogeneous nuclear ribonucleoproteins (hnRNPs), we have characterized nuclear polyadenylated RNA-binding (Nab) proteins from Saccharomyces cerevisiae.
Datar, KV, Paddy, MR, Swanson, MS, Swedlow, JR, Wilson, SM   +4 more
core   +1 more source

Schlafen-5 inhibits LINE-1 retrotransposition

iScience, 2023
Summary: Long interspersed element 1 (LINE-1) is the only currently known active autonomous transposon in humans, and its retrotransposition may cause deleterious effects on the structure and function of host cell genomes and result in sporadic genetic ...
Jiwei Ding, Shujie Wang, Qipeng Liu, Yuqing Duan, Tingting Cheng, Zhongjie Ye, Zhanding Cui, Ao Zhang, Qiuyu Liu, Zixiong Zhang, Ning Zhang, Qian Liu, Ni An, Jianyuan Zhao, Dongrong Yi, Quanjie Li, Jing Wang, Yongxin Zhang, Ling Ma, Saisai Guo, Jinhui Wang, Chen Liang, Jinming Zhou, Shan Cen, Xiaoyu Li   +24 more
doaj   +1 more source

An agent-based model for mRNA export through the nuclear pore complex. [PDF]

, 2014
mRNA export from the nucleus is an essential step in the expression of every protein- coding gene in eukaryotes, but many aspects of this process remain poorly understood.
Azimi, Mohammad, Bulat, Evgeny, Mofrad, Mohammad RK, Weis, Karsten   +3 more
core   +2 more sources

Ribonucleoprotein-like Structures from Coronavirus Particles

Journal of General Virology, 1978
The structure of the ribonucleoprotein (RNP) complex of three coronaviruses was investigated. A single-stranded helix of diam. 14 to 16 nm and up to 320 nm in length was released from disrupted particles of human coronavirus strain 229E and mouse hepatitis virus strain 3 after incubation in mild conditions. The helical complexes appeared to be composed
M. R. Macnaughton, H. A. Davies, M. V. Nermut   +2 more
openaire   +2 more sources

Alterations of membrane curvature during influenza virus budding [PDF]

, 2014
Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Agnieszka Martyna, Ali, Brown, Bruce, Chen, Enami, Gomez-Puertas, Jeremy Rossman, Johnson, Lai, Leser, Liao, Liu, McCown, McCown, Palese, Pattnaik, Pinto, Rossman, Rossman, Rossman, Rossman, Ruigrok, Schmidt, Takeda, Wang, Wang, Watanabe, Zebedee, Zhang   +29 more
core   +1 more source

Cas9-guide RNA ribonucleoprotein-induced genome editing in the industrial green alga Coccomyxa sp. strain KJ

Biotechnology for Biofuels, 2018
Background Oxygen-evolving photosynthetic microorganisms, collectively termed as microalgae, are gaining attention as alternative fuel sources. The unicellular alga Coccomyxa sp.
Yuya Yoshimitsu, Jun Abe, Shigeaki Harayama   +2 more
doaj   +1 more source

Single-particle mass analysis of intact ribosomes by mass photometry and Orbitrap-based charge detection mass spectrometry

iScience, 2021
Summary: Standard methods for mass analysis measure ensembles of thousand to millions of molecules. This approach enables analysis of monodisperse recombinant proteins, whereas some heterogeneous protein assemblies pose a significant challenge, whereby ...
Szu-Hsueh Lai, Sem Tamara, Albert J.R. Heck   +2 more
doaj   +1 more source

Influenza A nucleoprotein binding sites for antivirals: current research and future potential [PDF]

, 2014
This document is the Accepted Manuscript version of the following article: Andreas Kukol and Hershna Patel, ‘Influenza A nucleoprotein binding sites for antivirals: current research and future potential’, Future Biology, Vol 9(7): 625-627, July 2014. The
Kukol, A, Kukol, A, Patel, H., Patel, H.
core   +2 more sources