Results 61 to 70 of about 30,834 (284)

Structural Dynamics of the Vault Ribonucleoprotein Particle

, 2011
Peer ...
Casañas, Arnau, Querol-Audí, Jordi, Fita, Ignacio, Verdaguer, Núria   +3 more
openaire   +3 more sources

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source

EV71 3C protease induces apoptosis by cleavage of hnRNP A1 to promote apaf-1 translation.

PLoS ONE, 2019
Enterovirus 71 (EV71) induces apoptosis to promote viral particle release. Earlier work showed that EV71 utilizes its 3C protease to induce apoptosis in a caspase-3-dependent pathway, though the mechanism is unknown. However, work from Vagner, Holcik and
Mei-Ling Li, Jing-Yi Lin, Bo-Shiun Chen, Kuo-Feng Weng, Shin-Ru Shih, Jesse Davila Calderon, Blanton S Tolbert, Gary Brewer   +7 more
doaj   +1 more source

Pulmonary Artery Aneurysm (PAA) in Behçet's Disease Presenting With Recurrent Hemoptysis: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Pulmonary artery aneurysm is a serious but under‐recognized complication of Behçet's disease that may present with hemoptysis. Early diagnosis coupled with timely initiation of immunosuppressive therapy is crucial in preventing aneurysmal progression and associated life‐threatening complications.
Sorouri S, Safari Farmad M, Amiriani A, Baniasad A.   +3 more
europepmc   +2 more sources

Biomolecular Condensates as Emerging Biomaterials: Functional Mechanisms and Advances in Computational and Experimental Approaches

Advanced Materials, EarlyView.
Integration of computational and experimental approaches for deciphering the underlying mechanism of biomolecular condensates and potential biomaterials design (Created in Biorender. Raza, Z. (2025) https://BioRender.com/irgmeqi). Abstract Biomolecular condensates, a ubiquitous class of biomaterials found in living cells, have been shown to be ...
Qiang Zhu, Zahra Raza, Dzung Do‐Ha, Emma De Costa, Pavlina Sasheva, Luke McAlary, Hadi Mahmodi, Warwick P. Bowen, Lezanne Ooi, Irina Kabakova, Haibo Yu   +10 more
wiley   +1 more source

A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing

eLife, 2015
Prp3 is an essential U4/U6 di-snRNP-associated protein whose functions and molecular mechanisms in pre-mRNA splicing are presently poorly understood. We show by structural and biochemical analyses that Prp3 contains a bipartite U4/U6 di-snRNA-binding ...
Sunbin Liu, Sina Mozaffari-Jovin, Jan Wollenhaupt, Karine F Santos, Matthias Theuser, Stanislaw Dunin-Horkawicz, Patrizia Fabrizio, Janusz M Bujnicki, Reinhard Lührmann, Markus C Wahl   +9 more
doaj   +1 more source

Saccharomyces cerevisiae and Schizosaccharomyces pombe contain a homologue to the 54-kD subunit of the signal recognition particle that in S. cerevisiae is essential for growth. [PDF]

, 1989
We have isolated and sequenced genes from Saccharomyces cerevisiae (SRP54SC) and Schizosaccharomyces pombe (SRP54sp) encoding proteins homologous to both the 54-kD protein subunit (SRP54mam) of the mammalian signal recognition particle (SRP) and the ...
Hann, BC, Poritz, MA, Walter, P
core  

Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP [PDF]

, 1999
Raf-1 phosphorylates and activates MEK-1, a kinase that activates the extracellular signal regulated kinases (ERK). This kinase cascade controls the proliferation and differentiation of different cell types.
A Minden, A Sewing, AD Catling, B Hallberg, CJ Marshall, D Woods, DK Grandy, DK Morrison, DW Rose, F Schoentgen, Ferrell, J. E. Jr, Ferrell, J. E. Jr, H Mischak, HJ Schaeffer, JT Bruder, KL Guan, M Kortenjann, OV Gjorup, RM Lavbinsky, RM Tombes, S Häfner, S Li, SA Moodie, UR Rapp, W Kolch, W Kolch   +25 more
core   +1 more source

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

Anti‐Inflammatory Mechanisms of Selenium Nanosheets in Ulcerative Colitis: Protein Corona, GP130 Interaction, and Transcriptomic Profile

Advanced Science, EarlyView.
SeNSs provide a biocompatible, anti‐inflammatory UC therapy. SeNSs form protein coronas enriched with AKT/PI3K/NF‐κB pathway proteins, suppress GP130 via hydrophobic interactions, and inhibit pro‐inflammatory cytokines. In DSS‐induced UC mice, SeNSs reduce inflammation, tissue damage, and disease activity by modulating cytokine, chemokine, and ...
Dingyi Shen, Li Gong, Wei Yang, Jiaqi Luo, Zhen Jin, Youzhi Tang   +5 more
wiley   +1 more source