Results 181 to 190 of about 22,188 (264)
ABSTRACT Soybean (Glycine max L.) is the world's most important oilseed crop, supplying 25% of world‘s edible oil and 66% of feed protein. This review address genomic innovations to overcome yield constraints and climate vulnerability (especially drought stress) in high‐oil soybean breeding.
Mujeeb Ur Rehman +7 more
wiley +1 more source
Smart Design: Integrating Artificial Intelligence and Gene Editing for Advanced mRNA Therapeutics
The challenges of mRNA therapy and the application of artificial intelligence and gene editing in the field of mRNA drugs. ABSTRACT Artificial intelligence (AI) and gene editing are increasingly being applied to the design and evaluation of mRNA therapeutics.
Haixing Shi +11 more
wiley +1 more source
Neurod2 knockdown in <i>Xenopus laevis</i> tadpole brain retains cells in a proliferating, progenitor-like state. [PDF]
Beck CW, Banerjee S, Day RC.
europepmc +1 more source
A TETRA‐primer amplification refractory mutation system polymerase chain reaction (T‐ARMS‐PCR) method was developed for simultaneous detection of the L412F/V and G408V mutations. L412F/V mutants were created using the CRISPR/Cas tool and no fitness cost was observed.
Georgios Sofianos +3 more
wiley +1 more source
Multidimensional regulatory roles and therapeutic applications of SRSF7 in cancer. [PDF]
Li Y +5 more
europepmc +1 more source
ABSTRACT Hantaviruses are emerging zoonotic pathogens of increasing global public health significance. Their epidemiological landscape is rapidly changing due to ecological disruption, climate variability, urbanisation, and evolving human–animal interfaces.
Francesco De Maria +5 more
wiley +1 more source
Exosome-like nanovesicles from acerola for CRISPR-Cas9 ribonucleoprotein delivery to the central nervous system. [PDF]
Nagamatsu Y +8 more
europepmc +1 more source
Testis‐Enriched F‐Box Protein FBXO39 Is Important for Spermiogenesis and Male Fertility in Mice
ABSTRACT Background The SCF (Skp–Cullin–F‐box) complex is a major class of E3 ubiquitin ligases. F‐box proteins constitute the SCF complex and play a critical role in recognizing substrates for ubiquitination. In mice, several F‐box proteins, including FBXO36 and FBXO39, are predominantly expressed in testes.
Yuki Kaneda +2 more
wiley +1 more source
Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins. [PDF]
Xu D +13 more
europepmc +1 more source
ABSTRACT Precise genome editing has transformed plant biology and crop improvement by enabling targeted modification of endogenous loci. Beyond gene knockout and base editing, the site‐specific insertion of exogenous DNA, particularly large DNA fragments, has become a central goal for engineering complex traits, reconstructing metabolic pathways and ...
Fengfeng Zhang +6 more
wiley +1 more source

