Results 221 to 230 of about 9,338 (256)
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Interrogating the transcriptome with metabolically incorporated ribonucleosides
Molecular Omics, 2021This review summarizes recent developments in metabolic labeling of RNA to study RNA synthesis and turnover, RNA binding proteins, and RNA modifications and modifying enzymes.
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Ribonucleoside 2′,3′-orthocarbonates
J. Chem. Soc. D, 1969Ribonucleosides undergo acid-catalysed exchange with tetramethyl orthocarbonate to give 2′,3′-O-dimethoxymethylidene derivatives.
G. R. Niaz, C. B. Reese
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Selective deacylation of peracylated ribonucleosides
Tetrahedron Letters, 2009Abstract A protocol for chemoselective deprotection of N,O-acylated ribonucleosides has been developed. Peracylated pyrimidine ribonucleosides subjected to guanidinium nitrate and NaOMe in MeOH/CH 2 Cl 2 at 0 °C undergo high yielding O-deacylation, while even more pronounced chemoselectivity is observed with peracylated purine ribonucleosides as O5′-
Patrick J. Hrdlicka +4 more
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Degradation of pyrimidine ribonucleosides by Pseudomonas aeruginosa
Antonie van Leeuwenhoek, 1996Pyrimidine ribonucleoside degradation in the human pathogen Pseudomonas aeruginosa ATCC 15692 was investigated. Either uracil, cytosine, 5-methylcytosine, thymine, uridine or cytidine supported P. aeruginosa growth as a nitrogen source when glucose served as the carbon source.
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STUDIES ON REACTION OF RIBONUCLEOSIDES WITH OXYPHOSPHORANE
Phosphorus, Sulfur, and Silicon and the Related Elements, 1996Abstract Ester exchange reaction of ribonucleosides (2) with oxyphosphorane (1) afforded spirooxyphosphoranes (3). After hydrolysis followed by acetylation, the labile spirooxyphosphoranes such as 3a were converted into stable nucleotide derivatives (4). The possible mechanism for the conversion was also discussed.
Yufen Zhao +3 more
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Synthesis of acylphosphates of purine ribonucleosides
Tetrahedron Letters, 1996Abstract Nucleotides do not penetrate cells at a sufficient rate to realize their therapeutic potential. To overcome this limitation we have envisaged acyl nucleodi(tri)phosphates (ND(T)Ps) as suitable membrane permeable prodrugs because a) preliminary experiences have shown that these compounds are preferably cleaved at their mixed carboxylic ...
Annett Kreimeyer +3 more
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Some Aspects of Ribonucleoside Chemistry
Nucleosides and Nucleotides, 1985Abstract New routes to the preparations of 2′-deoxy-3′-C-methyl uridine (2c) and 1-(5′-0-trityl-3′-deoxy-β-D-glycero-pentofuran-2-ulosyl)uracil (4) from 5′-0-trityl-2′-0-tosyl uridine (1) and 5′-0-trityl-3′-0-tosyl uridine (3) respectively are described.
Jyoti Chattopadhyaya +3 more
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2-Fluoropurine ribonucleosides
Journal of Medicinal Chemistry, 1970Kathleen Hewson, John A. Montgomery
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Simplified diethylaminoethylcellulose chromatography of ribonucleosides
Analytical Biochemistry, 1971Barbara H. Smith, Joseph MacGee
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Acyl migration in ribonucleoside derivatives
Tetrahedron Letters, 1965Colin B. Reese, D.R. Trentham
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