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Compartmentation of Ribonucleotides in PC-12 Cells: Free and Protein Bound Ribonucleotides
1995Pheochromocytoma is a cancer derived from the neural crest, mainly occurring at adult age. Rat pheochromocytoma PC-12 cells have an imbalance between pyrimidine ribonucleotide pools in comparison with adrenal medulla tissue1. No imbalance has been noticed between the ribonucleotide pools of the purine pathway.
Slingerland, R. J. +6 more
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Purification of glycineamide ribonucleotide transformylase
Biochemical and Biophysical Research Communications, 1978Abstract Glycineamide ribonucleotide transformylase has been purified 240-fold from chicken liver along with formyl-methenyl-methylenetetrahydrofolate synthetase (combined), through seven purification steps including a glycineamide ribonucleotide affinity column and a 10-formyl synthetase specific MgATP elution from hydroxylapatite.
C A, Caperelli +3 more
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Ribonucleotide Reductase—a Radical Enzyme
Science, 1983Ribonucleotide reductases catalyze the enzymatic formation of deoxyribonucleotides, an obligatory step in DNA synthesis. The native form of the enzyme from Escherichia coli or from mammalian sources contains as part of its polypeptide structure a free tyrosyl radical, stabilized by an iron center.
P, Reichard, A, Ehrenberg
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Interaction of ribonucleotide reductase with ribonucleotide analogs
Biochemistry, 1971H, Follmann, H P, Hogenkamp
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Thin-layer electrophoresis of ribonucleotides
Analytical Biochemistry, 1969Abstract Electrophoresis on thin layers of cellulose of an alkaline hydrolyzate of RNA provides an easy and reproducible method for base ratio determinations. Separation of a nucleotide mixture (20–40 μg) is completed in 90 min at 4°C and requires only conventional equipment.
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