Results 201 to 210 of about 196,005 (260)

[Ribonucleotide reductase complex].

Postepy biochemii, 1984
openaire   +1 more source

Therapeutic mucosal vaccination of herpes simplex virus type 2 infected guinea pigs with an adenovirus-based vaccine expressing the ribonucleotide reductase 2 and glycoprotein D induces local tissue-resident CD4+ and CD8+ TRM cells associated with protection against recurrent genital herpes. [PDF]

Front Immunol
Quadiri A, Prakash S, Vahed H, Tadros JM, Sun M, Hormi-Carver KK, Patel SJ, BenMohamed L.   +7 more
europepmc   +1 more source

Ribonucleotide reductase and DNA damage

, 2006
Pelle Håkansson
openalex   +1 more source

On the chemical mechanism of assembly of the tyrosyl radical-dinulcear iron cluster cofactor of E. coli ribonucleotide reductase

, 1993
J. Martin Bollinger
openalex   +1 more source

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Ribonucleotide Reductase Subunit

Definitions, 2020
Encoded by Ribonucleotide Reductase Subunit Genes (RRM1 and RRM2), the M1 Chain and M2 Chain subunits compose Ribonucleoside-Diphosphate Reductase, a heterodimeric cytoplasmic enzyme essential in dividing cells that reduces ribonucleotides to ...
openaire   +2 more sources

Ribonucleotide reductase

Enzyme Active Sites and their Reaction Mechanisms, 2021
H. Morrison
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Ribonucleotide Reductase

RCSB Protein Data Bank, 2019
D. Goodsell
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Ribonucleotide Reductases

Annual Review of Biochemistry, 2006
Ribonucleotide reductases (RNRs) transform RNA building blocks to DNA building blocks by catalyzing the substitution of the 2′OH-group of a ribonucleotide with a hydrogen by a mechanism involving protein radicals. Three classes of RNRs employ different mechanisms for the generation of the protein radical. Recent structural studies of members from each
Pär, Nordlund, Peter, Reichard
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Potent ribonucleotide reductase inhibitors: Thiazole‐containing thiosemicarbazone derivatives

Archiv der Pharmazie, 2019
The antioxidant, antimalarial, antibacterial, and antitumor activities of thiosemicarbazones have made this class of compounds important for medicinal chemists.
M. Ertas, Z. Şahin, Emre F Bulbul, Ceysu Bender, S. N. Biltekin, Barkın Berk, Leyla Yurttaş, Aysu M Nalbur, Hayati Çelik, Ş. Demirayak   +9 more
semanticscholar   +1 more source

8-azidoadenosine and ribonucleotide reductase

Biochemical and Biophysical Research Communications, 1992
Inhibitors of ribonucleotide reductase are potential antiproliferative agents, since they deplete cells from DNA precursors. Substrate nucleoside analogues, carrying azido groups at the base moiety, are shown to have strong cytostatic properties, as measured by the inhibition of the incorporation of thymidine into DNA.
B, Roy, M, Lepoivre, J L, Decout, J, Lhomme, M, Fontecave   +4 more
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