ChemPhysChem, Volume 27, Issue 2, January 2026.QM/MM modeling of Sulerythrin (SulE) identifies three electronic states of its diiron center, differing in protonation and bridging ligands. The results reconcile crystallographic heterogeneity and reveal how subtle electronic and structural changes govern non‐heme diiron enzyme reactivity.
Samah Moubarak, Maria Andrea Mroginski
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Light-strand bias and enriched zones of embedded ribonucleotides are associated with DNA replication and transcription in the human-mitochondrial genome [PDF]
, 2023 Penghao Xu +19 more
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Circular RNAs as Biomarkers and Therapeutic Targets in Diabetic Cardiovascular Complications
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.This graphic abstract elaborates on the recent mechanism of circular RNAs (circRNAs) in the pathogenesis, diagnosis and treatment of diabetic cardiovascular complications. Diabetes mellitus induces oxidative/inflammatory stress, followed by endothelial dysfunction and leads to micro‐/macro‐vascular complications.
Shreya Singh Beniwal +10 more
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Enzymatic Incorporation of Emissive Pyrimidine Ribonucleotides
, 2008 Seergazhi G. Srivatsan, Yitzhak Tor
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Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components
Small Methods, Volume 10, Issue 2, 22 January 2026.The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu +6 more
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Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy
The FEBS Journal, Volume 293, Issue 2, Page 325-347, January 2026.The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro +2 more
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Supplementary Figure 5 from <i>p53-Inducible Ribonucleotide Reductase</i> (<i>p53R2/RRM2B</i>) Is a DNA Hypomethylation–Independent Decitabine Gene Target That Correlates with Clinical Response in Myelodysplastic Syndrome/Acute Myelogenous Leukemia [PDF]
, 2023 Petra A. Link +4 more
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Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.ABSTRACT This study assessed the anticancer activity of boron‐containing and structurally diverse small molecules in 4T1 breast cancer and Caco‐2 colon adenocarcinoma cells. Initial screening showed that five boronic acids lacked significant cytotoxicity, underscoring the structural specificity required for boron‐mediated bioactivity.
Azmi Yerlikaya +2 more
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Mechanical tuning of molecular machines for nucleotide recognition at the air-water interface
Nanoscale Research Letters, 2011 Molecular machines embedded in a Langmuir monolayer at the air-water interface can be operated by application of lateral pressure. As part of the challenge associated with versatile sensing of biologically important substances, we here demonstrate ...
Shinoda Satoshi +10 more
doaj
Structure of the tyrosyl radical in bacteriophage T4-induced ribonucleotide reductase.
, 1982 Margareta Sahlin +3 more
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