The Consequence of the Presence of Ribonucleotide for ds-DNA’s Electronic Properties: Preliminary Theoretical Studies [PDF]
CellsThe genome is continuously exposed to different harmful factors whose activity causes different types of lesions. On the other hand, during the DNA replication process, a ribonucleoside (rN) can be inserted more frequently than the occurrence of DNA ...
Boleslaw T. Karwowski
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Effects of supplementing hemp (Cannabis sativa L.) leaves in concentrate diet on carcass traits and meat characteristics of Longissimus muscle in goat kids. [PDF]
PLoS ONEThe influence of dietary hemp (Cannabis sativa L.) leaf (HL) supplementation in a concentrate diet on carcass traits, physicochemical properties, amino acids, ribonucleotides, lipid oxidation, and fatty acids of Longissimus thoracis et lumborum (LTL ...
Chanporn Chaosap +5 more
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Detection of ribonucleotides embedded in DNA by Nanopore sequencing [PDF]
Communications BiologyRibonucleotides represent the most common non-canonical nucleotides found in eukaryotic genomes. The sources of chromosome-embedded ribonucleotides and the mechanisms by which unrepaired rNMPs trigger genome instability and human pathologies are not ...
Lavinia Grasso +8 more
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PCNA and Rnh1 independently participate in the protection of mitochondrial genome against UV-induced mutagenesis in yeast cells [PDF]
Scientific ReportsIn Saccharomyces cerevisiae cells, the bulk of mitochondrial DNA (mtDNA) replication is mediated by the replicative high-fidelity DNA polymerase γ. However, upon UV irradiation low-fidelity translesion polymerases: Polη, Polζ and Rev1, participate in an ...
Martyna Latoszek +3 more
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Spectroscopic Characterization of 3-Aminoisoxazole, a Prebiotic Precursor of Ribonucleotides
Molecules, 2022 The processes and reactions that led to the formation of the first biomolecules on Earth play a key role in the highly debated theme of the origin of life.
Alessio Melli +8 more
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Frontiers in Pharmacology, 2021 Remdesivir (RDV) has generated much anticipation for its moderate effect in treating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Yan Li +8 more
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Zn2+-dependent DNAzymes that cleave all combinations of ribonucleotides
Communications Biology, 2021 Inomata et al. isolate zinc-dependent DNAzymes with compact catalytic core sequences displaying highly versatile hydrolysis activity. The cleavable substrate variation for the DNAzymes (ZincDz2 and ZincDz2-v2) is very broad and the authors further ...
Rika Inomata +2 more
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Current perspectives on mechanisms of ribonucleotide incorporation and processing in mammalian DNA
Genes and Environment, 2019 Ribonucleotides, which are RNA precursors, are often incorporated into DNA during replication. Although embedded ribonucleotides in the genome are efficiently removed by canonical ribonucleotide excision repair (RER), inactivation of RER causes genomic ...
Akira Sassa +2 more
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Foods, 2022 This study investigated the effects of dietary energy density in rice straw and cassava pulp fermented total mixed ration on pH, cooking loss, Warner–Bratzler shear force (WBSF), and collagen content of 2- or 14-d-aged native Thai cattle (NTC ...
Chanporn Chaosap +5 more
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In search of the mRNA modification landscape in plants
BMC Plant Biology, 2019 Background Precise regulation of gene expression is indispensable for the proper functioning of organisms in both optimal and challenging conditions. The most commonly known regulative mechanisms include the modulation of transcription, translation and ...
Jagna Chmielowska-Bąk +2 more
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