Results 71 to 80 of about 17,369 (190)
Ribonucleotide Reductase Subunit Switching in Hepatoblastoma Drug Response and Relapse
, 2022 Anthony Brown, Anthony Brown
openalex +1 more source
Molecular Microbiology, EarlyView.Bacillus subtilis RNase HII corrects ribonucleotide errors and mismatched ribonucleotides, but not damaged ribonucleotides. Mismatched ribonucleotides would also serve as substrates for mismatch repair while damaged ribonucleotides would be addressed through base excision repair.
Julianna R. Cresti, Lyle A. Simmons
wiley +1 more source
Boosting Reversible Photocontrol of a Photoxenase by an Engineered Conformational Shift
Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.Photocontrol of enzymes with photoswitchable unnatural amino acids hitherto yielded only limited light‐regulation factors (LRFs). Here we boosted the LRF of an imidazole glycerol phosphate synthase variant from ∼15 to ∼100 in a semi‐rational design approach and unraveled the mechanistic fundamentals of this effect via biophysical and computational ...
Sabrina Mandl +6 more
wiley +2 more sources
KRP3 Stability Controls Rice Plant Architecture and Productivity via MPK3‐Mediated Phosphorylation
Plant Biotechnology Journal, EarlyView.ABSTRACT Yield is a critical agronomic trait in cereal crops, shaped by factors like tiller and seed number, and seed weight. Understanding the factors governing these traits will help in improving the yield of plants. In this study, we identified an orphan gene, KRP3, belonging to cereal crops as a key regulator of rice plant architecture.
Gopal Banerjee +6 more
wiley +1 more source
Translation‐Promoting Effects of RNA Template Overhangs in the Absence of Ribosomes
Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.Ribosome‐free translation of an RNA sequence into a peptide sequence can be controlled by the folding of the template strand. Overhang sequences forming a triplex structure with the templating region and the peptidoyl RNA in pH‐dependent manner increase yields up to 40‐fold through entropic effects and mixed anhydride formation, allowing for controlled,
Nikolaos Giannakopoulos +2 more
wiley +2 more sources
Plant Biotechnology Journal, EarlyView.ABSTRACT Vitamin B1 (VB1) plays a crucial role in sustaining plant health and enabling adaptive responses to environmental stress. The complex maize genome implies a sophisticated VB1 synthesis pathway, with the mechanisms by which VB1 benefits plants remaining elusive.
Tengfei Zhang +8 more
wiley +1 more source
BioTechniques, 2006 A simple enzymatic labeling procedure is described to determine spot quality in oligonucleotide microarrays. By using fluorescently labeled dideoxynucleotides or ribonucleotides as substrate for terminal deoxynucleotidyl transferase (TdT), a single ...
Cesar E. Guerra
doaj +1 more source
Experimental Physiology, EarlyView.Abstract The global prevalence of obesity and related metabolic disorders has spurred interdisciplinary research to develop new intervention strategies. Current research is increasingly focusing on the exercise‐induced browning of white adipose tissue and the mechanisms by which it improves energy metabolism.
Yuhui Su +4 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A schematic diagram outlining the concept of enviromimetics, and the subclasses of exercise mimetics, epimimetics and cognitomimetics. The rationale is that environmental stimulation and lifestyle factors, including physical activity and cognitive stimulation, have shown beneficial effects across a range of human conditions ...
Anthony J. Hannan
wiley +1 more source