Results 21 to 30 of about 246,720 (281)

PARP-3 and APLF function together to accelerate nonhomologous end joining [PDF]

, 2010
PARP-3 is a member of the ADP-ribosyl transferase superfamily of unknown function. We show that PARP-3 is stimulated by DNA double-strand breaks (DSBs) in vitro and functions in the same pathway as the poly (ADP-ribose)-binding protein APLF to accelerate
Ahel, Ame, Anna E.O. Fisher, Audebert, Bekker-Jensen, Benjamin, Bernardo Reina-San-Martin, Boulton, Brown, Bryant, Bryant, Caldecott, Caldecott, Critchlow, Ding, Drouet, El-Khamisy, Farmer, Fisher, Grawunder, Guy Poirier, Hochegger, Hottiger, Iles, Isabelle Robert, Kanno, Keith W. Caldecott, Kickhoefer, Kleine, Le Page, Lehtio, Limei Ju, Lobrich, Loseva, Macrae, Mahaney, Maria C. Zuma, Mehrotra, Michele Rouleau, Morrison, Okano, Otto, Poirier, Robert, Roberts, Rogakou, Rogakou, Rouleau, Rulten, Smith, Soulas-Sprauel, Stevnsner, Stuart L. Rulten, Sugimura, Trucco, Wang, Yan, Yang, Yano, Yano   +59 more
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The potential role and application of PARP inhibitors in cancer treatment [PDF]

, 2009
Background: Since many anti-cancer agents act by inflicting DNA damage on tumour cells, there is increasing interest in the use of inhibitors of DNA repair to increase the cytotoxicity of these agents.
Chalmers, Anthony J
core   +2 more sources

O6-[(2″,3″-O-Isopropylidene-5″-O-^tbutyldimethylsilyl)pentyl]-5′-O-^tbutyldiphenylsilyl-2′,3′-O-isopropylideneinosine

Molbank, 2022
Cyclic adenosine diphosphate ribose (cADPR) is a cyclic nucleotide involved in the Ca2+ homeostasis. In its structure, the northern ribose, bonded to adenosine through an N1 glycosidic bond, is connected to the southern ribose through a pyrophosphate ...
Maria Marzano, Monica Terracciano, Vincenzo Piccialli, Ahmed Mahal, Roberto Nilo, Stefano D’Errico   +5 more
doaj   +1 more source

Partial (13)C isotopic enrichment of nucleoside monophosphates: useful reporters for NMR structural studies [PDF]

, 2005
Analysis of the (13)C isotopic labeling patterns of nucleoside monophosphates (NMPs) extracted from Escherichia coli grown in a mixture of C-1 and C-2 glucose is presented. By comparing our results to previous observations on amino acids grown in similar
Kishore, Anita I., Mayer, Michael R., Prestegard, James H.   +2 more
core   +2 more sources

Molecular bases of catalysis and ADP-ribose preference of human Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase and conversion by mutagenesis to a preferential cyclic ADP-ribose phosphohydrolase. [PDF]

PLoS ONE, 2015
Among metallo-dependent phosphatases, ADP-ribose/CDP-alcohol diphosphatases form a protein family (ADPRibase-Mn-like) mainly restricted, in eukaryotes, to vertebrates and plants, with preferential expression, at least in rodents, in immune cells. Rat and
Alicia Cabezas, João Meireles Ribeiro, Joaquim Rui Rodrigues, Iralis López-Villamizar, Ascensión Fernández, José Canales, Rosa María Pinto, María Jesús Costas, José Carlos Cameselle   +8 more
doaj   +1 more source

Effect of pressure on the Maillard reaction between ribose and cysteine in supercritical carbon dioxide

Czech Journal of Food Sciences, 2010
An aqueous ribose-cysteine model system, heated at 140°C under supercritical carbon dioxide (SC-CO2) and supercritical nitrogen (SC-N2), was investigated with emphasis on the formation of volatile compounds.
Honggao Xu, Wenhao He, Xuan Liu, Yanxiang Gao   +3 more
doaj   +1 more source

Selective monitoring of the protein-free ADP-ribose released by ADP-ribosylation reversal enzymes.

PLoS ONE, 2021
ADP-ribosylation is a key post-translational modification that regulates a wide variety of cellular stress responses. The ADP-ribosylation cycle is maintained by writers and erasers.
Samuel Kasson, Nuwani Dharmapriya, In-Kwon Kim   +2 more
doaj   +1 more source

A systematic review and meta-analysis of cognitive and behavioral tests in rodents treated with different doses of D-ribose

Frontiers in Aging Neuroscience, 2022
BackgroundD-ribose is an aldehyde sugar and a necessary component of all living cells. Numerous reports have focused on D-ribose intervention in animal models to assess the negative effects of D-ribose on cognition.
Ying Song, Yage Du, Yu An, Jie Zheng, Yanhui Lu   +4 more
doaj   +1 more source

Development of a selection system for the detection of L-ribose isomerase expressing mutants of Escherichia coli [PDF]

, 2007
L-Arabinose isomerase (E.C. 5.3.1.14) catalyzes the reversible isomerization between L-arabinose and L-ribulose and is highly selective towards L-arabinose.
Beauprez, Joeri, De Maeseneire, Sofie, De Mey, Marjan, De Muynck, Cassandra, Soetaert, Wim, Van Bogaert, Inge, Van der Borght, Jef, Vandamme, Erick   +7 more
core   +1 more source

Protective effect of D-ribose against inhibition of rats testes function at excessive exercise [PDF]

Journal of Stress Physiology & Biochemistry, 2011
An increasing number of research studies point to participation in endurance exercise training as having significant detrimental effects upon reproductive hormonal profiles in men.
Chigrinskiy E.A., Conway V.D.
doaj