Results 11 to 20 of about 234,091 (293)

Ribose Supplementation Alone or with Elevated Creatine Does Not Preserve High Energy Nucleotides or Cardiac Function in the Failing Mouse Heart. [PDF]

PLoS ONE, 2013
BackgroundReduced levels of creatine and total adenine nucleotides (sum of ATP, ADP and AMP) are hallmarks of chronic heart failure and restoring these pools is predicted to be beneficial by maintaining the diseased heart in a more favourable energy ...
Kiterie M E Faller, Debra J Medway, Dunja Aksentijevic, Liam Sebag-Montefiore, Jürgen E Schneider, Craig A Lygate, Stefan Neubauer   +6 more
doaj   +21 more sources

Metabolic pathway analysis reveals hierarchical pentose sugar utilization and metabolic flexibility of Bifidobacterium longum [PDF]

Gut Microbes
Plant-derived pentose sugars represent a major nutrient source in the gut, yet their metabolism remains incompletely defined. Strains of the human gut commensal Bifidobacterium longum subsp.
Lisa Friess, Fionnuala M. McAuliffe, Paul D. Cotter, Anthony L. Shiver, Kerwyn Casey Huang, Anne de Jong, Douwe van Sinderen   +6 more
doaj   +2 more sources

Statement on the safety of d‐ribose [PDF]

EFSA Journal, 2018
In 2018, the EFSA NDA Panel adopted the Scientific Opinion on the safety of d‐ribose as a novel food pursuant to Regulation (EU) 2015/2283 when used in a variety of food, concluding that d‐ribose is safe for the general population at intake levels up to ...
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch‐Ernst, John Kearney, Helle Katrine Knutsen, Alexandre Maciuk, Inge Mangelsdorf, Harry J McArdle, Androniki Naska, Carmen Pelaez, Kristina Pentieva, Alfonso Siani, Frank Thies, Sophia Tsabouri, Marco Vinceti, Tara Dean, Karl Heinz Engel, Marina Heinonen, Rosangela Marchelli, Monika Neuhäuser‐Berthold, Morten Poulsen, Annette Pöting, Yolanda Sanz, Josef Rudolf Schlatter, Andrea Germini, Henk van Loveren   +27 more
doaj   +7 more sources

d -Ribose as a Contributor to Glycated Haemoglobin

EBioMedicine, 2017
Glycated haemoglobin (HbA1c) is the most important marker of hyperglycaemia in diabetes mellitus. We show that d-ribose reacts with haemoglobin, thus yielding HbA1c.
Ying Liu, Yong Xu, Juan Li
exaly   +3 more sources

A plastid carbohydrate carrier mediates ribose recycling from nucleotide catabolism and glucose export from starch degradation [PDF]

Nature Communications
In plants, nucleotide degradation releases ribose in the cytosol. An unidentified transporter then brings the ribose into the plastids for phosphorylation. This process of ribose recycling is particularly prominent in root nodules of soybean (Glycine max)
Luisa Voß, Isabel Keller, Rebekka Schröder, Denise Mehner-Breitfeld, André Specht, Gerald Dräger, Jannis Rinne, Jakob Franke, Nieves Medina-Escobar, Marco Herde, Thomas Brüser, H. Ekkehard Neuhaus, Claus-Peter Witte   +12 more
doaj   +2 more sources

Dietary D-Ribose Supplementation in Sheep: Implications on Rumen, Fecal Microbiota, and Metabolic Function [PDF]

Microorganisms
The objective of this study was to investigate the effects of dietary D-ribose supplementation on the microbial diversity, community composition, and metabolic function of the rumen and fecal microbiota in Hu sheep.
Qinghua Qiu, Lin Li, Ke Pan, Kehui Ouyang, Mingren Qu, Huan Liang   +5 more
doaj   +2 more sources

Residues of the ribose binding site are required for human ribokinase activity [PDF]

Journal of Structural Biology: X
Ribokinase (RK) catalyzes the phosphorylation of D-ribose to ribose-5-phosphate, an essential metabolic intermediate for the pentose phosphate pathway, nucleotide biosynthesis, redox balance, and cellular energy metabolism.
Juliana C. Ferreira, Lyudmila Nedyalkova, Adrian J. Villanueva, Samar Fadl, Zeynep Nur Cinviz, Kenana Al Adem, Ozge Sensoy, Wael M. Rabeh   +7 more
doaj   +2 more sources

CoCl₂-Mimicked Endothelial Cell Hypoxia Induces Nucleotide Depletion and Functional Impairment That Is Reversed by Nucleotide Precursors

Biomedicines, 2022
Chronic hypoxia drives vascular dysfunction by various mechanisms, including changes in mitochondrial respiration. Although endothelial cells (ECs) rely predominantly on glycolysis, hypoxia is known to alter oxidative phosphorylation, promote oxidative ...
Barbara Kutryb-Zajac, Ada Kawecka, Alicja Braczko, Marika Franczak, Ewa M. Slominska, Roberto Giovannoni, Ryszard T. Smolenski   +6 more
doaj   +1 more source

Ribose Intake as Food Integrator: Is It a Really Convenient Practice?

Biomolecules, 2022
Reports concerning the beneficial effects of D-ribose administration in cardiovascular and muscle stressful conditions has led to suggestions for the use of ribose as an energizing food supplement for healthy people. However, this practice still presents
Roberta Moschini, Francesco Balestri, Mario Cappiello, Giovanni Signore, Umberto Mura, Antonella Del-Corso   +5 more
doaj   +1 more source

Chiral Recognition of D/L-Ribose by Visual and SERS Assessments

Molecules, 2023
Ribose is the central molecular unit in ribose nucleic acid (RNA). Ribose is a key molecule in the study of many persistent scientific mysteries, such as the origin of life and the chiral homogeneity of biological molecules.
Guohua Yao, Chao Liu, Shereen M. Elsherbiny, Qing Huang   +3 more
doaj   +1 more source