Results 1 to 10 of about 17,158 (246)
Targeting MARylation and DePARylation in Cancer Therapy: New Promising Therapeutic Opportunities. [PDF]
Cancers (Basel)Cabeza-Fernández V +6 more
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Emerging Roles of Adenosine Metabolism in Astrocytes During Brain Injury. [PDF]
CNS Neurosci TherZhu S, Zhong S, Lin X, Zhao C, Li Y.
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Quantification of SARM1 NADase Activity in Human Peripheral Blood Mononuclear Cells. [PDF]
FASEB JDabill LF +5 more
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Cyclic ADP-ribose and its metabolic enzymes
Biochimie, 1995 Cyclic ADP-ribose (cADPR) is a recently discovered cyclic nucleotide with Ca2+ signaling functions. There is a growing recognition that it is an endogenous modulator of the Ca(2+)-induced Ca2+ release mechanism in cells. The cyclic structure of cADPR has now been confirmed by x-ray crystallography.
Timothy F Walseth
exaly +6 more sources
Some of the next articles are maybe not open access.
Cellular Signalling, 1999
The Ca2+-mobilizing natural compound cyclic ADP-ribose was discovered in sea urchin egg homogenates. Recently the involvement of cyclic ADP-ribose in Ca2+ signaling has been demonstrated in diverse biological systems spanning protozoa, plants, and cells from invertebrate, mammalian, and human sources.
Andreas H Guse
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The Ca2+-mobilizing natural compound cyclic ADP-ribose was discovered in sea urchin egg homogenates. Recently the involvement of cyclic ADP-ribose in Ca2+ signaling has been demonstrated in diverse biological systems spanning protozoa, plants, and cells from invertebrate, mammalian, and human sources.
Andreas H Guse
exaly +3 more sources
NAD glycohydrolases and the metabolism of cyclic ADP-ribose
Biochimie, 1995Cyclic ADP-ribose is a recently discovered metabolite of NAD that functions in cellular calcium signalling. The discovery that NAD glycohydrolases can catalyze the synthesis and hydrolysis of cyclic ADP-ribose has renewed interest in this class of ADP-ribose transferring enzymes that were discovered over 50 years ago.
Myron K Jacobson
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New aspects of the physiological significance of NAD, poly ADP-ribose and cyclic ADP-ribose
Biochimie, 1995Cyclic ADP-ribose is generated from NAD+ in glucose-stimulated beta-cells by CD38. Cyclic ADP-ribose mobilizes Ca2+ from the endoplasmic reticulum to secrete insulin. The amino acid residues of Cys-119 and Cys-201 in CD38 are essential for the synthesis and hydrolysis of cyclic ADP-ribose.
Shin Takasawa, A Tohgo
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Position of Cyclization in Cyclic ADP-Ribose
Biochemical and Biophysical Research Communications, 1993Cyclic adenosine diphosphoribose (cADPR) is a putative second messenger of calcium homeostasis synthesized from NAD by cleavage of the nicotinamide-ribose bond and cyclization of the ribose to the adenine ring. In this study, the ultraviolet absorption spectra of cADPR have been studied as a function of pH and compared to other compounds containing an ...
H, Kim, E L, Jacobson, M K, Jacobson
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The crystal structure of cyclic ADP-ribose
Nature Structural Biology, 1994link_to_subscribed_fulltext
Aarhus, R, Lee, HC, Levitt, D
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