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Ribosomal RNA methylation by GidB modulates discrimination of mischarged tRNA [PDF]

open access: yeseLife
Despite redundant cellular pathways to minimize translational errors, errors in protein synthesis are common. Pathways and mechanisms to minimize errors are classified as pre-ribosomal or ribosomal. Pre-ribosomal pathways are primarily concerned with the
Zhuo Bi   +9 more
doaj   +2 more sources

Sequential domain assembly of ribosomal protein S3 drives 40S subunit maturation

open access: yesNature Communications, 2016
Ribosome biogenesis involves the hierarchical assembly of several proteins and RNA components. Here the authors describe a mechanism for ribosomal protein S3 incorporation into 40S ribosomal subunits that involves S3 dimerization and stepwise ...
Magali Blaud   +2 more
exaly   +2 more sources

Potential secondary metabolite from Indonesian Actinobacteria (InaCC A758) against Mycobacterium tuberculosis [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2021
Objective(s): This study explored Indonesian Actinobacteria which were isolated from Curcuma zedoaria endophytic microbes and mangrove ecosystem for new antimycobacterial compounds.
Maya Rakhmawatie   +5 more
doaj   +1 more source

Aneurysm Infection Caused by Desulfovibrio desulfuricans

open access: yesEmerging Infectious Diseases, 2023
An 84-year-old man in Japan who had undergone endovascular aortic repair 9 years earlier had an infected aneurysm develop. We detected Desulfovibrio desulfuricans MB at the site.
Tatsuya Fujihara   +7 more
doaj   +1 more source

The oral microbiome of patients with ischemic stroke predicts their severity and prognosis

open access: yesFrontiers in Immunology, 2023
Background and objectivesStroke is a common group of cerebrovascular diseases that can lead to brain damage or death. Several studies have shown a close link between oral health and stroke.
Wenbo Sun   +5 more
doaj   +1 more source

Interaction between the assembly of the ribosomal subunits: Disruption of 40S ribosomal assembly causes accumulation of extra-ribosomal 60S ribosomal protein uL18/L5. [PDF]

open access: yesPLoS ONE, 2020
Inhibition of the synthesis of an essential ribosomal protein (r-protein) abrogates the assembly of its cognate subunit, while assembly of the other subunit continues.
Nusrat Rahman   +2 more
doaj   +1 more source

Translational control of one-carbon metabolism underpins ribosomal protein phenotypes in cell division and longevity

open access: yeseLife, 2020
A long-standing problem is how cells that lack one of the highly similar ribosomal proteins (RPs) often display distinct phenotypes. Yeast and other organisms live longer when they lack specific ribosomal proteins, especially of the large 60S subunit of ...
Nairita Maitra   +8 more
doaj   +1 more source

Roles of ribosomal proteins in hematologic disorders and cancers: a review

open access: yesEmergency and Critical Care Medicine, 2023
. Ribosomes are important organelles for synthesizing proteins in cells. They are composed of ribosomal RNA and more than 80 ribosomal proteins. It is well known that an essential function of ribosomal proteins is to participate in protein translation ...
Jie Wang, Feng Yan
doaj   +1 more source

Ribosomal proteins: mutant phenotypes by the numbers and associated gene expression changes [PDF]

open access: yesOpen Biology, 2020
Ribosomal proteins are highly conserved, many universally so among organisms. All ribosomal proteins are structural parts of the same molecular machine, the ribosome.
Michael Polymenis
doaj   +1 more source

DHAV-1 2A1 Peptide – A Newly Discovered Co-expression Tool That Mediates the Ribosomal “Skipping” Function

open access: yesFrontiers in Microbiology, 2018
Duck hepatitis A virus 1 (DHAV-1) belongs to the genus Avihepatovirus in the family Picornaviridae. Little research has been carried out on the non-structural proteins of this virus.
Xiaoyao Yang   +42 more
doaj   +1 more source

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